Navigation Links
'Freezing' Secondary Breast Cancer Tumors Shows Promise
Date:3/26/2012

MONDAY, March 26 (HealthDay News) -- In a small and preliminary study, researchers report that they successfully froze secondary tumors in patients with incurable breast cancer.

The findings raise the prospect of a potential new treatment for metastatic tumors in individual patients, although the research is in the very early stages.

"This therapy provides a minimal rate of cancer recurrence and no major complications," study co-author Dr. Peter Littrup, director of imaging core and radiology research at the Karmanos Cancer Institute in Detroit, said in a news release from the Society of Interventional Radiology.

The study is scheduled to be presented Wednesday at the society's annual meeting in San Francisco. Research presented at medical meetings should be viewed as preliminary until published in a peer-reviewed medical journal.

"This is a preliminary study, and at this point we're hoping that the evidence could be a stepping stone for a bigger study to look at more patients," Littrup said. "If we can get more data that supports percutaneous cryoablation for metastatic breast cancer, it could be a huge finding."

In percutaneous cryoablation, tiny probes insert pressurized argon gas into tumors and kill them by turning them into balls of ice.

The eight patients in the study had stage 4 metastatic breast cancer, meaning their tumors had spread widely from the breast. The tumors frequently appear in organs such as the liver, lungs, bones and kidneys.

In stage 4, the disease is considered incurable.

"At this point, treatments are considered palliative -- with the intent to keep metastases at bay while hopefully providing individuals more time and improved quality of life, rather than a complete cure," Littrup said.

"Cryoablation as a targeted therapy is beneficial because it can significantly reduce discomfort and incidence of disease," Littrup said. "It's a much better option, we think, than surgery -- especially since many metastatic patients are not candidates for surgery -- and it may potentially lead to longer survival."

The eight patients in the study lived for an average of 46 months, and two survived for at least five years.

Dr. Hannah Linden, an oncology specialist and assistant professor at the University of Washington School of Medicine in Seattle, said it's too early to know whether the treatment works since it hasn't been compared to other therapies.

"Many patients with metastatic breast cancer live a long time with gentle treatments, yet other patients who have relatively resistant tumors do poorly," she said. "While the idea of freezing a tumor to prevent it from growing is feasible and exciting, it is not proven that such an approach actually 'cures' patients or provides long-term benefit."

Although similar treatments target secondary tumors, she added, they "do not address the systemic problem of metastatic cancer. So, while it seems good to 'kill' the metastasis, the cancer is still lurking."

Breast cancer is the most common cancer among women, killing nearly 370,000 people worldwide each year. Approximately 10,000 to 15,000 new cases of stage 4 breast cancer occur in the United States each year, Littrup noted.

More information

For more about breast cancer, visit the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCES: Society of Interventional Radiology, news release, March 26, 2012; Hannah Linden, M.D., assistant professor, University of Washington School of Medicine, Seattle


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Wayne State proves targeted tumor freezing therapy increases ovarian cancer survival
2. Freezing Wrinkles a Possible Alternative to Botox
3. For Common Warts, Freezing Therapy Works Best: Study
4. Studies of womens attitudes to social egg freezing find reasons differ with age
5. Freezing Tumors Shows Promise Against Prostate, Breast Cancer
6. Freezing, Medicating Away a Dangerous Irregular Heart Rhythm
7. Freezing Technique May Stop Breast Cancer
8. Freezing breast tumors helps stop cancer’s spread in mice, U-M study finds
9. Malnutrition as a secondary symptom
10. Researchers focus on secondary stroke prevention after study reveals room for improvement
11. Urgent steps needed to tackle inadequate support for women with secondary breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
'Freezing' Secondary Breast Cancer Tumors Shows Promise
(Date:2/10/2016)... ... 10, 2016 , ... InDemand Interpreting , a leading ... with Heart City Health Center to improve access to language services ... Health Center has provided the Elkhart community with access to high quality, affordable ...
(Date:2/10/2016)... ... 10, 2016 , ... 10 Best Water is excited to announce ... brand owners that topped the list as a result of their commitment to offering ... brand was Tibet 5100, a top notch water company that specializes in providing the ...
(Date:2/10/2016)... ... February 10, 2016 , ... ... welcomes S.S. Nesbitt as the latest addition to its growing list of Partner ... locations throughout the Southeast, from Orlando to Huntsville and in between. , Harnessing ...
(Date:2/10/2016)... ... February 10, 2016 , ... Pediatric ... in their patients. Research shows that the Goal Attainment Scale (GAS) captures 20% ... this challenge and learn more about the Goal Attainment Scale, Education Resources Inc. ...
(Date:2/10/2016)... ... February 10, 2016 , ... IDEX Health & Science, LLC ... steel (PLS) columns combine the strength of traditional stainless steel with the chemical ... samples while operating at ultra-high pressures of 20,000 psi. The higher operating pressures ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... WINDSOR, ON , Feb. 10, 2016 /PRNewswire/ ... Perry , has announced the release of an ... This is a revolutionary breakthrough in the treatment ... environmental radiation exposure. It will assist in the ... are present. It will also protect only the ...
(Date:2/10/2016)... 10, 2016  Silicon Biosystems Menarini Inc., a ... help uncover the biological complexities of disease at ... developer of innovative technologies for genomics research, today ... at enabling translational researchers to obtain high-quality sequencing ... tumor and normal cells in an optimized and ...
(Date:2/10/2016)... -- Until recently, the options for reducing the appearance of ... approved the non-invasive Coolsculpting treatment, which removes fat cells ... in 2010 for the abdomen and this approval was ... this add-on approval, the experts at Laser Therapy Health ... CoolMini, to address smaller areas of fat. ...
Breaking Medicine Technology: