Navigation Links
'Freezing' Secondary Breast Cancer Tumors Shows Promise

MONDAY, March 26 (HealthDay News) -- In a small and preliminary study, researchers report that they successfully froze secondary tumors in patients with incurable breast cancer.

The findings raise the prospect of a potential new treatment for metastatic tumors in individual patients, although the research is in the very early stages.

"This therapy provides a minimal rate of cancer recurrence and no major complications," study co-author Dr. Peter Littrup, director of imaging core and radiology research at the Karmanos Cancer Institute in Detroit, said in a news release from the Society of Interventional Radiology.

The study is scheduled to be presented Wednesday at the society's annual meeting in San Francisco. Research presented at medical meetings should be viewed as preliminary until published in a peer-reviewed medical journal.

"This is a preliminary study, and at this point we're hoping that the evidence could be a stepping stone for a bigger study to look at more patients," Littrup said. "If we can get more data that supports percutaneous cryoablation for metastatic breast cancer, it could be a huge finding."

In percutaneous cryoablation, tiny probes insert pressurized argon gas into tumors and kill them by turning them into balls of ice.

The eight patients in the study had stage 4 metastatic breast cancer, meaning their tumors had spread widely from the breast. The tumors frequently appear in organs such as the liver, lungs, bones and kidneys.

In stage 4, the disease is considered incurable.

"At this point, treatments are considered palliative -- with the intent to keep metastases at bay while hopefully providing individuals more time and improved quality of life, rather than a complete cure," Littrup said.

"Cryoablation as a targeted therapy is beneficial because it can significantly reduce discomfort and incidence of disease," Littrup said. "It's a much better option, we think, than surgery -- especially since many metastatic patients are not candidates for surgery -- and it may potentially lead to longer survival."

The eight patients in the study lived for an average of 46 months, and two survived for at least five years.

Dr. Hannah Linden, an oncology specialist and assistant professor at the University of Washington School of Medicine in Seattle, said it's too early to know whether the treatment works since it hasn't been compared to other therapies.

"Many patients with metastatic breast cancer live a long time with gentle treatments, yet other patients who have relatively resistant tumors do poorly," she said. "While the idea of freezing a tumor to prevent it from growing is feasible and exciting, it is not proven that such an approach actually 'cures' patients or provides long-term benefit."

Although similar treatments target secondary tumors, she added, they "do not address the systemic problem of metastatic cancer. So, while it seems good to 'kill' the metastasis, the cancer is still lurking."

Breast cancer is the most common cancer among women, killing nearly 370,000 people worldwide each year. Approximately 10,000 to 15,000 new cases of stage 4 breast cancer occur in the United States each year, Littrup noted.

More information

For more about breast cancer, visit the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCES: Society of Interventional Radiology, news release, March 26, 2012; Hannah Linden, M.D., assistant professor, University of Washington School of Medicine, Seattle

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Wayne State proves targeted tumor freezing therapy increases ovarian cancer survival
2. Freezing Wrinkles a Possible Alternative to Botox
3. For Common Warts, Freezing Therapy Works Best: Study
4. Studies of womens attitudes to social egg freezing find reasons differ with age
5. Freezing Tumors Shows Promise Against Prostate, Breast Cancer
6. Freezing, Medicating Away a Dangerous Irregular Heart Rhythm
7. Freezing Technique May Stop Breast Cancer
8. Freezing breast tumors helps stop cancer’s spread in mice, U-M study finds
9. Malnutrition as a secondary symptom
10. Researchers focus on secondary stroke prevention after study reveals room for improvement
11. Urgent steps needed to tackle inadequate support for women with secondary breast cancer
Post Your Comments:
Related Image:
'Freezing' Secondary Breast Cancer Tumors Shows Promise
(Date:11/24/2015)... ... November 25, 2015 , ... Genesis Chiropractic Software helps practice ... an agreement between the practice owner and the patient that automatically manages all ... projections. Click here to learn more. , According to ...
(Date:11/24/2015)... , ... November 24, 2015 , ... Charitable giving is ... donations are made in the last five weeks of the year totalling over $358 ... in 2012 to connect the nation’s charities with those individuals who want to “give ...
(Date:11/24/2015)... IL (PRWEB) , ... November 24, 2015 , ... ... are national leaders when it comes to several aspects of orthopedic care. They ... joint replacements, orthopedic surgeries and general orthopedic care. , Becker's Hospital Review ...
(Date:11/24/2015)... ... November 24, 2015 , ... In response to recent news highlighting ... from prescription opioids in the United States grew 400 percent between 1999 and 2010, ... were involved in 37 percent of all fatal drug overdoses. (1) , While oxycodone ...
(Date:11/24/2015)... (PRWEB) , ... November 24, 2015 , ... Serenity Point ... a series of recent video interviews with some of the staff members at their ... the residential treatment facility, as well as some of the things that make their ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... Nov. 24, 2015  Natera, Inc. (Nasdaq: ... genetic testing and the analysis of circulating ... present at the 27 th  Annual Piper ... 2015 at 1:00 p.m. ET.  Matthew Rabinowitz, Ph.D., CEO of ... business activities and financial outlook. ...
(Date:11/24/2015)... York , 24 de noviembre de 2015 ... Avery Breathing Pacemaker System, se complace anunciar el ... como consultor clínico.   ... Foto -   ... es un fisiólogo y consultor en neonatología y ...
(Date:11/24/2015)... Connecticut , November 24, 2015 ... of Acadiana has entered into a multi-year agreement ... imaging centers. This investment will provide the Breast Center ... --> Sectra (STO: SECT B) announces that ... agreement to deploy Breast Imaging PACS in its ...
Breaking Medicine Technology: