Navigation Links
Freezing Ovaries Preserves Fertility, Scientists Report
Date:11/10/2008

New technique could help cancer patients or women who want to delay childbirth

MONDAY, Nov. 10 (HealthDay News) -- Scientists are reporting the ability to freeze and transplant ovaries, a development that could help preserve fertility in women facing cancer therapy.

"We can transplant ovaries without any loss of ovarian tissue or eggs, and it functions perfectly normally whether it's fresh or frozen," said co-researcher Dr. Sherman Silber, director of the Infertility Center of St. Louis at St. Luke's Hospital.

Silber said the technique could also be used by women who want to delay having children. He reported the findings Nov. 10 at the American Society for Reproductive Medicine annual meeting, in San Francisco.

In one paper, Silber reported that he and his colleagues had transplanted an ovary from one identical twin to her twin sister, allowing the twin with premature ovarian failure to conceive a child. One year after the transplant, the twin with the transplanted ovary had become pregnant.

But, Silber said, the ability to remove an ovary, freeze it and put it back into the same woman represents the real breakthrough. "We can freeze the ovaries of young women who are going to lose their fertility over time and transplant them back later, and they [the ovaries] won't have aged," he explained.

The technique can benefit cancer patients about to undergo radiation, chemotherapy or bone marrow transplant, which would leave them sterile, Silber said. "But if we take the ovary out, freeze it, save it and transplant it back later, they will be fertile again," he said.

Currently, women can have their eggs frozen and put back after cancer treatment is complete, Silber noted. "But there are disadvantages," he said. "If you put all those eggs in one basket, and she goes through IVF [in vitro fertilization], she can't have any better chance of pregnancy than 50 percent. If she is not pregnant from that, then she's finished."

With ovary transplantation, however, "She's got a normally functioning ovary just like she would have if she were younger. Freezing the ovary and putting it back is much more sure for the patient than egg freezing," he said.

Silber and his colleagues also reported at the meeting on one woman who had her ovary removed, frozen and then restored. But they said they've done the procedure nine times. "It's very repeatable," Silber said. "It's not just a fluke."

Silber said that if a woman receives a cancer diagnosis, "ask about freezing your ovary. In addition, young women who are going to put off childbearing should also think about having one of their ovaries frozen," he added.

Dr. Richard J. Paulson, chief of the Division of Reproductive Endocrinology and Infertility at the University of Southern California Keck School of Medicine, in Los Angeles, thinks the new reports are encouraging but preliminary.

"This is very exciting," Paulson said. "Fertility preservation is our next major frontier, because what we have found is that women with cancer are increasingly surviving their chemotherapy but are infertile. It would be very helpful if we could have a method to preserve their fertility."

Although women are having their eggs frozen, many women can't go through the procedure to harvest the eggs, Paulson said. "It would be very appealing to take the ovary out and freeze it for the future," he said.

However, Paulson noted that, so far, no woman had become pregnant after her ovary had been removed, frozen and put back.

More information

For more on infertility, visit the U.S. National Library of Medicine.



SOURCES: Sherman Silber, M.D., director, Infertility Center of St. Louis at St. Luke's Hospital; Richard J. Paulson, M.D., professor of obstetrics and gynecology, chief, Division of Reproductive Endocrinology and Infertility, University of Southern California Keck School of Medicine, Los Angeles; Nov. 10, 2008, presentation, annual meeting, American Society for Reproductive Medicine, San Francisco


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Pacific Fertility Center Announces Breakthrough in Egg Freezing Technology
2. Tissue-Freezing Technique Effective Against Prostate Cancer
3. Removing Ovaries Before Menopause Leads to Memory, Movement Troubles
4. New photo op for ovaries may solve some mysteries of infertility
5. Abbott Donates Cool Globe to Lake County Forest Preserves for Permanent Display at Greenbelt Cultural Center
6. Ibuprofen Preserves Lung Function in Kids With Cystic Fibrosis
7. Study finds that sleep selectively preserves emotional memories
8. Technique Preserves Future Fertility in Girls With Cancer
9. New prion protein discovered by Canadian scientists may offer insight into mad cow disease
10. Scientists Probe Sepsis Deadly Secrets
11. Scientists puzzled by severe allergic reaction to cancer drug in the middle Southern US
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/25/2017)... ... 25, 2017 , ... The doctors at Wall Centre Dental are now expanding ... and require sedation to receive dental care. The doctors offer three treatment options to ... cleanings to oral surgery, at their dental office in Vancouver. Wall Centre Dental is ...
(Date:4/25/2017)... ... April 25, 2017 , ... Patients ... that achieves results in a fraction of the time as traditional braces – ... Significance Dental Specialists, now offers this revolutionary treatment with or without a referral. ...
(Date:4/25/2017)... ... April 25, 2017 , ... As Spring reignites vigilance ... research related to Zika virus during pregnancy, as well as other prenatal exposures ... science. , The Teratology Society is an international and multidisciplinary ...
(Date:4/25/2017)... (PRWEB) , ... April 25, 2017 , ... Buyers and ... recreational users to dispensaries and head shops –can’t help but be heartened by the ... the tell-tale cannabis odor aptly described as “skunk smell.” At last they can ...
(Date:4/25/2017)... Clara, CA (PRWEB) , ... April 25, 2017 ... ... announces the addition of predictive analytics to its patient care management module. Using ... compliance even before a patient has been initiated on continuous positive airway pressure ...
Breaking Medicine News(10 mins):
(Date:4/18/2017)... , April 18, 2017  Cardinal Health (NYSE: ... 1 fiscal 2017 earnings per share (EPS) guidance ... 2019.  This is in conjunction with this morning,s announcement ... Vein Thrombosis and Nutritional Insufficiency businesses. Cardinal ... continuing operations will be at the bottom of its ...
(Date:4/18/2017)... , April 18, 2017 Viverae ® , ... announce the integration of IBM ® Watson Campaign ... deliver targeted communications for a personalized experience. Through digital ... on their health in real time. The enhanced experience ... most to members, wherever they are in their journey ...
(Date:4/18/2017)... -- Astute Medical, Inc., developer of biomarkers for better healthcare, ... the 2017 National Kidney Foundation (NKF) Spring Clinical ... 22. Physicians will present data on two biomarkers, ... acute kidney injury (AKI) during the management of patients ... Elevated levels of TIMP-2 and IGFBP-7 have been shown ...
Breaking Medicine Technology: