Navigation Links
Freezing Ovaries Preserves Fertility, Scientists Report

New technique could help cancer patients or women who want to delay childbirth

MONDAY, Nov. 10 (HealthDay News) -- Scientists are reporting the ability to freeze and transplant ovaries, a development that could help preserve fertility in women facing cancer therapy.

"We can transplant ovaries without any loss of ovarian tissue or eggs, and it functions perfectly normally whether it's fresh or frozen," said co-researcher Dr. Sherman Silber, director of the Infertility Center of St. Louis at St. Luke's Hospital.

Silber said the technique could also be used by women who want to delay having children. He reported the findings Nov. 10 at the American Society for Reproductive Medicine annual meeting, in San Francisco.

In one paper, Silber reported that he and his colleagues had transplanted an ovary from one identical twin to her twin sister, allowing the twin with premature ovarian failure to conceive a child. One year after the transplant, the twin with the transplanted ovary had become pregnant.

But, Silber said, the ability to remove an ovary, freeze it and put it back into the same woman represents the real breakthrough. "We can freeze the ovaries of young women who are going to lose their fertility over time and transplant them back later, and they [the ovaries] won't have aged," he explained.

The technique can benefit cancer patients about to undergo radiation, chemotherapy or bone marrow transplant, which would leave them sterile, Silber said. "But if we take the ovary out, freeze it, save it and transplant it back later, they will be fertile again," he said.

Currently, women can have their eggs frozen and put back after cancer treatment is complete, Silber noted. "But there are disadvantages," he said. "If you put all those eggs in one basket, and she goes through IVF [in vitro fertilization], she can't have any better chance of pregnancy than 50 percent. If she is not pregnant from that, then she's finished."

With ovary transplantation, however, "She's got a normally functioning ovary just like she would have if she were younger. Freezing the ovary and putting it back is much more sure for the patient than egg freezing," he said.

Silber and his colleagues also reported at the meeting on one woman who had her ovary removed, frozen and then restored. But they said they've done the procedure nine times. "It's very repeatable," Silber said. "It's not just a fluke."

Silber said that if a woman receives a cancer diagnosis, "ask about freezing your ovary. In addition, young women who are going to put off childbearing should also think about having one of their ovaries frozen," he added.

Dr. Richard J. Paulson, chief of the Division of Reproductive Endocrinology and Infertility at the University of Southern California Keck School of Medicine, in Los Angeles, thinks the new reports are encouraging but preliminary.

"This is very exciting," Paulson said. "Fertility preservation is our next major frontier, because what we have found is that women with cancer are increasingly surviving their chemotherapy but are infertile. It would be very helpful if we could have a method to preserve their fertility."

Although women are having their eggs frozen, many women can't go through the procedure to harvest the eggs, Paulson said. "It would be very appealing to take the ovary out and freeze it for the future," he said.

However, Paulson noted that, so far, no woman had become pregnant after her ovary had been removed, frozen and put back.

More information

For more on infertility, visit the U.S. National Library of Medicine.

SOURCES: Sherman Silber, M.D., director, Infertility Center of St. Louis at St. Luke's Hospital; Richard J. Paulson, M.D., professor of obstetrics and gynecology, chief, Division of Reproductive Endocrinology and Infertility, University of Southern California Keck School of Medicine, Los Angeles; Nov. 10, 2008, presentation, annual meeting, American Society for Reproductive Medicine, San Francisco

Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Pacific Fertility Center Announces Breakthrough in Egg Freezing Technology
2. Tissue-Freezing Technique Effective Against Prostate Cancer
3. Removing Ovaries Before Menopause Leads to Memory, Movement Troubles
4. New photo op for ovaries may solve some mysteries of infertility
5. Abbott Donates Cool Globe to Lake County Forest Preserves for Permanent Display at Greenbelt Cultural Center
6. Ibuprofen Preserves Lung Function in Kids With Cystic Fibrosis
7. Study finds that sleep selectively preserves emotional memories
8. Technique Preserves Future Fertility in Girls With Cancer
9. New prion protein discovered by Canadian scientists may offer insight into mad cow disease
10. Scientists Probe Sepsis Deadly Secrets
11. Scientists puzzled by severe allergic reaction to cancer drug in the middle Southern US
Post Your Comments:
(Date:11/26/2015)... ... 2015 , ... Somu Sivaramakrishnan announced today that he joined ... offers travelers, value and care based Travel Services, including exclusive pricing on a ... cabin upgrades and special amenities such as, shore excursions, discounted fares, travel gifts ...
(Date:11/26/2015)... BOSTON, Mass. (PRWEB) , ... November 26, 2015 ... ... a thorough second medical opinion process, participated in the 61st annual Employee Benefits ... Benefit Plans and took place Sunday, November 8th through Wednesday, November 11th, 2015. ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... aggressive than those found on mammography, according to a study published online in ... cancers not seen on mammography may necessitate a change in treatment. , Breast ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... been recognized once again for its stellar workplace culture with the company’s Cincinnati ... , Medical Solutions’ Cincinnati office was named a finalist in Cincinnati Business ...
(Date:11/25/2015)... ... November 25, 2015 , ... On November 10, 2015, Bohrer ... Court of Connecticut on behalf of a home health care worker who provided companionship ... former home health care workers employed by Humana, Inc., Humana at Home, Inc., and ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... , Nov. 25, 2015  The American ... and Gynecologists (ACOG), and the March of Dimes ... Protecting Our Infants Act of 2015 ... number of newborns born exposed to drugs, such ... the bill,s introduction, all three organizations have worked ...
(Date:11/25/2015)... , Nov. 25, 2015  ARKRAY USA ... continues to provide evidence demonstrating the accuracy of its ... Congress on Insulin Resistance, Diabetes and Cardiovascular Disease in ... both the Company,s GLUCOCARD ® 01 meter and ... accuracy requirements. The ability to accurately measure glucose levels ...
(Date:11/25/2015)... , Nov. 25, 2015  Trovagene, Inc. (NASDAQ: ... announced that Chief Executive Officer Antonius Schuh, Ph.D., is ... th Annual Piper Jaffray Healthcare Conference. ... New York Palace Hotel in New York ... p.m. EST. Mr. Schuh will be available for one-on-one ...
Breaking Medicine Technology: