Navigation Links
Fracture Risk Seen With Hormone Therapy for Prostate Cancer
Date:11/10/2010

TUESDAY, Nov. 9 (HealthDay News) -- Long-term use of androgen deprivation therapy to treat prostate cancer may increase older patients' risk of broken bones, according to a new study.

These findings suggest that careful consideration is needed before doctors decide to use this therapy in older men with localized disease, the researchers said.

They analyzed data from more than 46,500 men, aged 66 and older, who survived at least five years after a diagnosis of localized prostate cancer and received long-term androgen deprivation therapy.

Older men with co-existing health problems are usually prescribed androgen deprivation therapy because they are not suitable candidates for radiation therapy or surgery to remove the prostate.

But this study found that men treated with androgen deprivation therapy had a 20 percent increased risk of a first fracture and a 57 percent increased risk of a second fracture after two years of treatment.

Older age, a higher number of co-existing health problems, and a history of fracture and stroke were associated with increased risk of fracture, the researchers said.

"Treating men who have pre-existing conditions with longer duration of androgen deprivation therapy exacerbates their risk of fracture, and becomes more pronounced over time," Grace Lu-Yao, a professor of medicine at the Cancer Institute of New Jersey and UMDNJ-Robert Wood Johnson Medical School, said in an American Association for Cancer Research (AACR) news release.

"Careful evaluation of the patient's risk of fracture, while initiating treatment, is important because fracture has a strong impact on quality of life and mortality," she added.

In addition, treatments involving removal of the testicles to stop testosterone production (which prostate cancer needs in order to grow) and/or long-term gonadotropin-releasing hormone use are also associated with an increased risk of fracture among men with prostate cancer.

The study findings were to be presented at the annual AACR Cancer Prevention Research Conference, Nov. 7 to 10 in Philadelphia.

More information

The American Cancer Society has more about androgen deprivation therapy.

-- Robert Preidt

SOURCE: American Association for Cancer Research, news release, Nov. 9, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. National research study to assess new treatment for painful vertebral fractures
2. Bone Drugs Linked to Rare Fractures, FDA Warns
3. Surgical technique relieves painful spine fractures in patients with metastatic cancer
4. Study finds high rate of c-sections after pelvic fractures
5. Expert Panel Links Popular Bone Drugs to Rare Fracture
6. New task force report on bisphosphonate use and atypical femur fractures in osteoporosis patients
7. Study Offers Support for Surgery After Compression Fracture
8. New Data Supports Link Between Diabetes Drugs, Fractures
9. Popular diabetes drugs associated with fractures in type 2 diabetic patients
10. Lucky break: Quit smoking after fracture surgery for better healing
11. Radiation for Prostate Cancer May Boost Fracture Risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Fracture Risk Seen With Hormone Therapy for Prostate Cancer
(Date:2/5/2016)... ... February 05, 2016 , ... Francisco Canales, ... services in their Napa Valley office. The technique utilizes the body’s own healing ... Canales and Dr. Furnas, are part of only a select few cosmetic surgeons ...
(Date:2/5/2016)... ... ... US Sports Camps , official operators of Nike Yoga Camps, announces ... training. ChildLight Yoga Studio is centrally situated in the picturesque New England city of ... founder Lisa Flynn expresses her excitement, “We are thrilled to be partnering with US ...
(Date:2/5/2016)... ... February 05, 2016 , ... Boar’s Head Brand®, one of ... for this weekend’s Big Game. Take the stress out of your party preparation – ... guests happy at every stage of the game. , “The key to hosting a ...
(Date:2/5/2016)... ... February 05, 2016 , ... ... CitiDent, announces that it is now welcoming orthodontist, Dr. Amanda Cheng, to ... a complete range of oral health care, including general dentistry, cosmetic treatments, periodontics, ...
(Date:2/5/2016)... ... February 05, 2016 , ... On June 9-10, Las ... continuing medical education (CME) event presented by the Association for Comprehensive Care in ... for ACCORD, whose mission is to provide education, tools, and resources to primary ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... , February 5, 2016 Site ... Today, VoicePower Ltd - The Speech Recognition People, announced their latest ... to improve patient care, reduce turnaround times and to save the ... ,- VoicePower client since 2013 Challenge: --> ... --> - Six doctors ,- Wirral CCG ,- VoicePower ...
(Date:2/4/2016)... , Feb. 4, 2016  Edwards Lifesciences Corporation (NYSE: ... for structural heart disease and critical care monitoring, announced ... repurchase (ASR) agreement with Morgan Stanley & Co. LLC ... repurchase is part of the Company,s previously authorized program ... common stock.  --> ...
(Date:2/4/2016)... , Feb. 4, 2016  SciClone Pharmaceuticals, Inc. ... it has entered into a settlement agreement with ... fully resolving the SEC,s investigation into possible violations ... the terms of the settlement agreement, SciClone has ... including disgorgement, pre-judgment interest and a penalty.  This ...
Breaking Medicine Technology: