Date:10/5/2011

ed within narrow treatment margins. Currently, many oncologists rely on other methods to align patients for radiation therapy, such as skin tattoos or x-rays of the pelvic bones, rather than the Calypso system or similar techniques that localize the prostate bed directly. In these cases, they should adjust their treatment margins to take into account the displacement of the prostate bed observed before and during treatment delivery, Klayton says.

In the future, Klayton and her collaborators plan to calculate specific treatment margins that clinicians should consider for post-prostatectomy patients receiving IMRT. Future studies should also examine a much larger group of patients over many years to determine how reducing the positional uncertainty of the prostate bed during treatment sessions may improve clinical outcomes, such as tumor control and toxicity to surrounding tissue.

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Contact: Diana Quattrone Diana.Quattrone@fccc.edu 215-728-7784 Fox Chase Cancer Center Source:Eurekalert

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