Navigation Links
Fox Chase researchers identify risk factors for the spread of breast cancer to lymph nodes
Date:11/2/2010

SAN DIEGO, CA (November 1, 2010)Breast cancer, one of the most prevalent cancers in women, afflicts an additional 200,000 women each year and causes about 40,000 deaths annually. The disease often extends to neighboring lymph nodes, in part, through lymphovascular invasion (LVI)a process in which cancer cells invade blood vessels or the lymphatic systemand can often translate into a poor prognosis for patients. Some scientists argue that evidence of LVI does not necessarily mean that the disease will recur in the lymph nodes after radiation to the breast alone, but research from Fox Chase Cancer Center now shows that the appearance of LVI in the breast tissue does in fact predict recurrence of breast in the regional lymph nodes.

By carefully examining recurrence patterns of thousands of women with breast cancer from records spanning more than 30 years, Wilhelm Lubbe, M.D.,Ph.D., chief resident in Fox Chase's Radiation Oncology Department, and his colleagues have now shown that the appearance of LVI in breast tissue predicts the future recurrence of cancer to nearby lymph nodes. "The microscopic diagnosis of LVI is challenging which highlights the importance of excellent pathologists," says Lubbe, who will present the results this week at the Annual Meeting of the American Society for Radiation Oncology.

Knowing that the disease is going to extend to neighboring lymph nodes, such as those in the armpit, is important prognostically. But it has still been unclear whether supplementary radiation therapy targeting these areas improves outcomes.

"There still is a lot of debate as to whether additional radiation to the regional lymph nodes is needed in a woman with LVI," Lubbe says.

In the study, Lubbe's team analyzed an extensive database of 3,082 breast cancer patients who underwent whole-breast radiation or minimal surgical resection of breast tissue between 1970 and 2009. This dataset, at least twice as large as many others
'/>"/>

Contact: Diana Quattrone
Diana.Quattrone@fccc.edu
215-728-7784
Fox Chase Cancer Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Cash is healthier? Credit and debit increase impulsive food purchases
2. CerMedia Completes Purchase of Cell-Pore Principal Assets from NanoDynamics
3. Fox Chase clinical trial tests first of its kind antibody
4. R-Biopharm Group Purchases a Majority Ownership in Trilogy Lab, Expanding US Operations
5. Ivory Homes Plans Ahead for the April 30th Home Buyer Tax Credit Deadline with 100 New Homes Ready for Quick Purchase
6. CapSite™ Provides Detailed Transparency on Healthcare Technology Purchases
7. ARI Purchases Intercytex Assets
8. Ensemble Healthcare Properties Purchases North Valley Medical Plaza
9. A New Twist On Convert to Purchase
10. Grand Opening of LIFE Ionizer Australia Launches with a Free Ionizer Upgrade with Purchase of Alkaline Water Ionizer from LIFE Ionizer Australia
11. International Merchant Advisors to Complete Purchase of Medical Marijuana Company Organic Science, Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... December 19, 2014 Slone ... diagnostic, personalized medicine, healthcare information technology, and laboratory ... position of Chief Operating Officer. The announcement comes ... marked by a strengthened presence in Boston and ... "Leslie lives and breathes the client experience," said ...
(Date:12/19/2014)... 2014 (HealthDay News) -- Being in good shape seems to ... They looked at data from more than 57,000 Americans, including ... tests between 1991 and 2009. Those in the poorest ... high blood pressure at the start of the study, compared ... of fitness. Of the more than 8,000 people diagnosed ...
(Date:12/19/2014)... through the same U.S. airport gate, one infected passenger ... four-hour time span, illustrating just how easily the virus ... in this report were not prolonged and occurred in ... fact that measles is highly contagious," wrote a team ... the U.S. Centers for Disease Control and Prevention. ...
(Date:12/17/2014)... Unidesk Corporation today announced that ... welcomed its inaugural class in August 2013, has ... support bring your own device (BYOD) and deliver ... The solution, comprised of Citrix XenDesktop ... and storage infrastructure and Unidesk virtual ...
(Date:12/17/2014)... (PRWEB) December 17, 2014 No matter ... been able to eradicate the head louse parasite—a common ... for parents. Each year between six and twelve million ... the Miami-based lice removal treatment company comes to the ... and environmentally friendly. With its track record of customer ...
Breaking Medicine News(10 mins):Health News:Slone Partners Promotes Leslie Loveless to Chief Operating Officer 2Health News:Being Fit Keeps Blood Pressure in Check 2Health News:Arriving Now at Gate 42: Measles 2Health News:Arriving Now at Gate 42: Measles 3Health News:Alabama College of Osteopathic Medicine Deploys Desktop Virtualization Solution from Citrix, Dell and Unidesk 2Health News:Alabama College of Osteopathic Medicine Deploys Desktop Virtualization Solution from Citrix, Dell and Unidesk 3Health News:Lice Troopers Announces New Lice Treatment Clinic in Coral Gables to Service Key Biscayne, Coconut Grove, Kendall, Brickell & South Miami 2
... her biological parents a few ... to drown in an irrigation ... the little infant survived that ... critical heart surgery. ...
... says acupuncture helps to reduce the symptoms related with ... ,Fibromyalgia is a condition with unknown cause, characterized ... and sleep problems. So treatment generally involves a combination ... 50 fibromyalgia patients participated in the study (for 2 ...
... thoughts and other mental health problems are more likely ... - a study of adolescents in a psychiatric hospital ... Medical School in Providence, Rhode Island and colleagues reported ... weight are likely to be suffer from dissociation, post-traumatic ...
Microsoft founder Bill Gates has said that his decision to devote more time to philanthropy was a...
... Duke University Medical Center have found from animal studies that ... but perceives it, divides it into categories and send to ... a recognizable scent. ,Humans may rely on the ... brain structures for scent, including an olfactory bulb, the researchers ...
... looks of freeze-dried fruits. Though they appear to be ... is present in fresh state is just the same ... are assimilated easily into the blood stream. ... Ph.D., Professor and Chair of Environmental Health Sciences at ...
Cached Medicine News:Health News:Smell Decoding System In Brain –Research Find 2
(Date:12/17/2014)... , Dec. 17, 2014 Royal Philips ... (NASDAQ: VOLC ), a global leader in catheter-based ... they have entered into a definitive merger agreement. Pursuant to ... all of the issued and outstanding shares of Volcano for ... of USD 1 billion (approx. EUR 800 million), to be ...
(Date:12/17/2014)... YORK , Dec. 17, 2014 ... imaging (MRI), the MRI market is seeing new ... and breast MRI scans account for the majority ... a higher resolution of images, which are creating opportunities ... imaging (MRI) market is growing at a rate ...
(Date:12/17/2014)... Dec. 17, 2014  RXi Pharmaceuticals Corporation (NASDAQ: ... on discovering, developing and commercializing innovative therapies addressing ... completion of enrollment in its first Phase 2a ... observations confirmed the 1-month findings that were reported ... Logo - http://photos.prnewswire.com/prnh/20130917/NE80755LOGO , ...
Breaking Medicine Technology:Philips to acquire Volcano to expand global leadership position in image-guided therapy market 2Philips to acquire Volcano to expand global leadership position in image-guided therapy market 3Philips to acquire Volcano to expand global leadership position in image-guided therapy market 4Philips to acquire Volcano to expand global leadership position in image-guided therapy market 5Philips to acquire Volcano to expand global leadership position in image-guided therapy market 6Philips to acquire Volcano to expand global leadership position in image-guided therapy market 7Philips to acquire Volcano to expand global leadership position in image-guided therapy market 8Kalorama: 3T Advancements Bringing New Growth to the MRI Market 2Kalorama: 3T Advancements Bringing New Growth to the MRI Market 3RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 2RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 3RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 4RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 5
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: