Navigation Links
Fox Chase researchers identify risk factors for the spread of breast cancer to lymph nodes
Date:11/2/2010

SAN DIEGO, CA (November 1, 2010)Breast cancer, one of the most prevalent cancers in women, afflicts an additional 200,000 women each year and causes about 40,000 deaths annually. The disease often extends to neighboring lymph nodes, in part, through lymphovascular invasion (LVI)a process in which cancer cells invade blood vessels or the lymphatic systemand can often translate into a poor prognosis for patients. Some scientists argue that evidence of LVI does not necessarily mean that the disease will recur in the lymph nodes after radiation to the breast alone, but research from Fox Chase Cancer Center now shows that the appearance of LVI in the breast tissue does in fact predict recurrence of breast in the regional lymph nodes.

By carefully examining recurrence patterns of thousands of women with breast cancer from records spanning more than 30 years, Wilhelm Lubbe, M.D.,Ph.D., chief resident in Fox Chase's Radiation Oncology Department, and his colleagues have now shown that the appearance of LVI in breast tissue predicts the future recurrence of cancer to nearby lymph nodes. "The microscopic diagnosis of LVI is challenging which highlights the importance of excellent pathologists," says Lubbe, who will present the results this week at the Annual Meeting of the American Society for Radiation Oncology.

Knowing that the disease is going to extend to neighboring lymph nodes, such as those in the armpit, is important prognostically. But it has still been unclear whether supplementary radiation therapy targeting these areas improves outcomes.

"There still is a lot of debate as to whether additional radiation to the regional lymph nodes is needed in a woman with LVI," Lubbe says.

In the study, Lubbe's team analyzed an extensive database of 3,082 breast cancer patients who underwent whole-breast radiation or minimal surgical resection of breast tissue between 1970 and 2009. This dataset, at least twice as large as many others
'/>"/>

Contact: Diana Quattrone
Diana.Quattrone@fccc.edu
215-728-7784
Fox Chase Cancer Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Cash is healthier? Credit and debit increase impulsive food purchases
2. CerMedia Completes Purchase of Cell-Pore Principal Assets from NanoDynamics
3. Fox Chase clinical trial tests first of its kind antibody
4. R-Biopharm Group Purchases a Majority Ownership in Trilogy Lab, Expanding US Operations
5. Ivory Homes Plans Ahead for the April 30th Home Buyer Tax Credit Deadline with 100 New Homes Ready for Quick Purchase
6. CapSite™ Provides Detailed Transparency on Healthcare Technology Purchases
7. ARI Purchases Intercytex Assets
8. Ensemble Healthcare Properties Purchases North Valley Medical Plaza
9. A New Twist On Convert to Purchase
10. Grand Opening of LIFE Ionizer Australia Launches with a Free Ionizer Upgrade with Purchase of Alkaline Water Ionizer from LIFE Ionizer Australia
11. International Merchant Advisors to Complete Purchase of Medical Marijuana Company Organic Science, Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/3/2015)... ... 2015 , ... Global Vision , the world leader in the development ... print and artwork inspection solutions, ScanProof and ArtProof at Packaging Innovations 2015. ... London, booth #F33 , Be the first to get a sneak peek of Intelligent ...
(Date:9/3/2015)... ... September 03, 2015 , ... Hunters Creek Retrievers ... Foundation with a champion AKC Black Lab Puppy. Celebrate Fall 2015 with unlimited Free ... friends and family to enjoy Thanksgiving and Christmas with an extra big smile. ...
(Date:9/3/2015)... (PRWEB) , ... September 03, 2015 , ... A scar is an unavoidable result of ... near-miraculous example of the body's ability to heal itself. The appearance of a scar is ... the individual's age, genes, and skin pigmentation. ”Many scars fade to near invisibility on their ...
(Date:9/3/2015)... ... 03, 2015 , ... Representatives with State Farm Agent EJ ... Mississippi Gulf Babypalooza on September 19, 2015. , “We will be providing information ... beyond. We will be discussing setting up college funds, offering information specific to ...
(Date:9/3/2015)... Santa Rosa, CA (PRWEB) , ... September 03, 2015 , ... About 220,800 new cases ... annually. One in seven men will be diagnosed with prostate cancer during their lifetime. While ... increases to six of every 10 men by age 65, according to the American ...
Breaking Medicine News(10 mins):Health News:Global Vision to Spotlight Intelligent Proofreading at Packaging Innovations 2015 2Health News:Global Vision to Spotlight Intelligent Proofreading at Packaging Innovations 2015 3Health News:Hunters Creek Retrievers Is Honored to Support the Lone Survivor Foundation with a Championship Trained Black Labrador Retriever Puppy 2Health News:Hunters Creek Retrievers Is Honored to Support the Lone Survivor Foundation with a Championship Trained Black Labrador Retriever Puppy 3Health News:Do I Have To Live With That Scar? 2Health News:Do I Have To Live With That Scar? 3Health News:Do I Have To Live With That Scar? 4Health News:State Farm Agent EJ Roberts to Help Expecting Mothers at the Mississippi Gulf Babypalooza 2Health News:Noted Santa Rosa Urologist Dr. Michael Lazar Provides Insights on Prostate Cancer Treatments in Recognition of Prostate Cancer Awareness Month 2Health News:Noted Santa Rosa Urologist Dr. Michael Lazar Provides Insights on Prostate Cancer Treatments in Recognition of Prostate Cancer Awareness Month 3
... YORK The Max Cure Foundation and the Samuel Waxman Cancer ... cancer research. With that goal in mind, the two Foundations ... G. Van Meir, Ph.D., of Emory University School of Medicine ... using a small molecule that will target the Ewing sarcoma ...
... July 1 issue of the journal SLEEP shows that ... vigor, fatigue and mood in collegiate basketball players. The ... the athletic performance of actively competing athletes. Results ... time per night during sleep extension was 110.9 minutes ...
... awarded $2.4 million to Allina Hospitals & Clinics to ... pain management for patients at Abbott Northwestern Hospital in ... Health and Healing and the Center for Healthcare Innovation ... study. "Integrative medicine emphasizes a full range of ...
... the Salk Institute for Biological Studies have found clues to ... The protein, p53, can cause cells to stop dividing or ... damage, and it is responsible for much of the tissue ... such as the ones commonly used for cancer therapy. The ...
... the foot just before ground contact during running and walking ... a new study published by a University of Georgia kinesiology ... the June online edition of the American Journal of ... of repetitive ankle sprains demonstrated lower clearance heights between their ...
... June 30 (HealthDay News) -- Women diagnosed with breast cancer ... rates than women who just have breast cancer, according to ... cancer but no chronic illness, those who had conditions such ... or lower survival rate, the study authors reported in the ...
Cached Medicine News:Health News:Targeting the Ewing sarcoma family of tumors 2Health News:Extended sleep improves the athletic performance of collegiate basketball players 2Health News:Extended sleep improves the athletic performance of collegiate basketball players 3Health News:Allina receives NIH grant to study real world usage of integrative therapies 2Health News:The genome guardian's dimmer switch: Regulating p53 is a matter of life or death 2Health News:The genome guardian's dimmer switch: Regulating p53 is a matter of life or death 3Health News:Foot positioning during walking and running may influence ankle sprains 2Health News:Breast Cancer Plus Other Health Issues Linked to Worse Outcomes 2
(Date:9/3/2015)... Sept. 3, 2015 OticPharma, Ltd., a privately ... for ear, nose, and throat (ENT) disorders, today announced ... complex to be the location of its new U.S. ... of September and will have office locations in both ... OticPharma, Inc. 19900 MacArthur Blvd., Suite 550 ...
(Date:9/2/2015)... , Sept. 2, 2015 This report ... the current and future prospects of the global ... health and assists medical practitioners in deciding the ... progression during treatment. Multi-parameter patient monitoring is effective ... disease. Geriatric population is observed to be at ...
(Date:9/2/2015)... , Sept. 2, 2015 About ... is used to treat an unruptured and ruptured ... wall). The treatment is either known as an ... the endovascular coil blocks the blood flow in ... performed under general anaesthesia by an interventional neuroradiologist ...
Breaking Medicine Technology:OticPharma Establishes U.S. Headquarters in Orange County, California 2Multi-parameter Patient Monitoring Equipment Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2015 - 2023 2Multi-parameter Patient Monitoring Equipment Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2015 - 2023 3Global Neuroendovascular Coil Market 2015-2019 2
... Sept. 19 Immtech Pharmaceuticals,Inc. (Amex: ... Food and Drug Administration,(FDA) has granted Orphan ... African Trypanosomiasis (HAT), also known as African,sleeping ... numerous,financial and regulatory benefits during pafuramidine,s development,including ...
... Both Cultures and Spores of the ... CHICAGO, Sept. 19 Targanta Therapeutics Corporation,today released ... activity of its,lead antibiotic drug candidate, oritavancin, to ... are being presented today,at the 47th Annual Interscience ...
Cached Medicine Technology:US FDA Grants Orphan Drug Status to Immtech's Pafuramidine for Treatment of African Sleeping Sickness 2US FDA Grants Orphan Drug Status to Immtech's Pafuramidine for Treatment of African Sleeping Sickness 3Oritavancin Demonstrates Superior In Vitro Activity to Vancomycin and Metronidazole Against C. Difficile Bacteria 2Oritavancin Demonstrates Superior In Vitro Activity to Vancomycin and Metronidazole Against C. Difficile Bacteria 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: