Navigation Links
Found in translation: Prioritizing research questions in breast cancer
Date:11/21/2007

The key priorities that will impact on the future treatment of breast cancer have been identified by a group of experts on the disease. Research published in the online open access journal Breast Cancer Research may focus research resources onto the issues highlighted as top priorities.

A team led by Professor Mitch Dowsett, Head of Biochemistry at The Royal Marsden NHS Foundation Trust, based in London and Surrey, together with colleagues from the USA, Switzerland and Italy carried out an international, web-based consultation to identify the most pressing issues that could be tackled by translational research. Translational research - which is concerned with the transfer of findings from the lab to the clinic - holds huge promise for the individualisation of cancer treatment.

In this study, a database of over 4000 potential participants (breast cancer professionals, including clinicians, research scientists, academics and pathologists) was created using attendee details from two major breast cancer conferences, one held in the USA and one in Europe. Participants were asked to register online and then log the most important questions that they felt the research community should tackle.

A steering committee reduced the 409 questions registered to 70 unique issues, from which participants were asked to vote for their 'top six'. In all, 420 participants from 48 countries voted; around half of voters classed themselves as clinicians.

The top research priority found was the identification of molecular signatures to select patients who could be spared chemotherapy. The second most pressing issue also involved chemotherapy, namely the identification of features to help clinicians choose the optimal chemotherapy regimen for individual patients.

While translational research in breast cancer has increased greatly over recent years, individual projects often reflect the immediate interests of the research group, rather than attempting to answer a specific question with potential to alter patient management. Identifying issues deemed important by the research community could help focus translational research resources, ensuring that opportunities for important clinical advances aren't missed.

"This appears to be a novel way to identify the most important challenges for improving breast cancer treatment and prevention" explains Professor Dowsett. "The work will allow investigators globally to select the most relevant clinical research questions in their efforts to translate the major advances in basic science to improvements in the clinical management of this common malignancy. I am grateful to the participants from 48 countries who made this possible."


'/>"/>

Contact: Charlotte Webber
press@biomedcentral.com
44-020-763-19980
BioMed Central
Source:Eurekalert

Related medicine news :

1. One Species Genome Found Within Another
2. National Patient Safety Foundation Partners with Vocera Communications
3. R. P. Simmons Family Foundation Pledges $2 Million for New Childrens Hospital of Pittsburgh of UPMC Campus
4. Super Jake Foundation Offers Hope for Pediatric Cancer
5. The American Liver Foundation Appoints Rick Smith, a Twenty-Year Veteran of The MS Society, as Chief Executive Officer
6. Patient Advocate Foundation Launches Program to Help Uninsured Virginians with Chronic, Debilitating and Life-Threatening Illness Access Quality Healthcare
7. AIDS Healthcare Foundation Applauds City Commissioners Support of Diversity, Urges Call for Mayors Resignation
8. National Osteoporosis Foundation Teams Up With Ladies Home Journal Magazine to Launch a 10-city Mall Walk Tour
9. Judge Rules That Florida Disease Management Program Serving 8,000 HIV/AIDS Patients Should Be Re-bid, Says AIDS Healthcare Foundation
10. The Tug McGraw Foundation Announces 2007 Fundraising Gala
11. The Arthur M. Blank Family Foundation Pushes for Pre-K Expansion in Georgia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/2/2016)... ... May 02, 2016 , ... Pregnancy Awareness Month offers a great time ... , “If you are ready to have a baby, it’s best to get ... Journal Babies is your Personal Conception & Pregnancy Organizer, written for women who plan ...
(Date:5/2/2016)... ... May 02, 2016 , ... Consultative health ... and GM Jim Callandrillo and Duane Reed, VP of business development of AJMC ... Intelligence and Research Group (PBIRG) General Meeting from May 15-17 at the ...
(Date:5/2/2016)... (PRWEB) , ... May 02, 2016 , ... For many ... performance artist Curt Walter has developed it into a science. , Using the ... Walter achieve subtly differentiated shades that add depth and meaning to his works. What’s ...
(Date:5/2/2016)... ... May 02, 2016 , ... ... today announced the opening of Twin Lakes Recovery Center. Located east of ... in the state. The residential facility is set on 34 acres of ...
(Date:5/1/2016)... ... May 02, 2016 , ... ... 1968 Jimi Hendrix Merriweather Post Pavilion in Columbia, Maryland concert posters. Dail Beeghley ... The concert was held on August 16. According to Hawley, “The Pavilion was ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... 2016   Click here for supplemental information ... DPLO), the nation,s largest independent specialty pharmacy, announced ... to acquire Valley Campus Pharmacy, Inc., doing business ... specialty pharmacy that provides individualized patient care, based ... In 2015, TNH generated approximately $400 million in ...
(Date:4/28/2016)... -- Research and Markets has announced the ... 2016-2020" report to their offering.      ... global plastic surgery products market is expected to grow ... , ,The growing adoption of laser in aesthetics is ... market. Lasers are used to treat a broad range ...
(Date:4/28/2016)... TOKYO , April 28, 2016 /PRNewswire/ ... Ahuja , George Phillips und ... wachsenden Unternehmens    ArisGlobal®, ein ... Life Sciences, gab heute bekannt, dass neue ... wachsenden Unternehmens gestoßen sind, die vielfältige Erfahrungen ...
Breaking Medicine Technology: