Navigation Links
Forthcoming study explores use of intermittent fasting in diabetes as cardiovascular disease

Los Angeles, CA (April 26, 2013) Intermittent fasting is all the rage, but scientific evidence showing how such regimes affect human health is not always clear cut. Now a scientific review in the British Journal of Diabetes and Vascular Disease published by SAGE, suggests that fasting diets may help those with diabetes and cardiovascular disease, alongside established weight loss claims.

Intermittent fasting fasting on a given number of consecutive or alternate days has recently been hailed as a path to weight loss and improved cardiovascular risk. A team led by James Brown from Aston University has evaluated the various approaches to intermittent fasting in the scientific literature. They searched specifically for advantages and limitations in treating obesity and type 2 diabetes using fasting diets.

The basic format of intermittent fasting is to alternate days eating 'normally' with days when calorie consumption is restricted. This can either be done on alternative days, or where two days each week are classed as 'fasting days'. These types of intermittent fasting have been shown in trials to be as effective as or more effective than counting calories every day to lose weight. Evidence from clinical trials shows that fasting can limit inflammation, improve levels of sugars and fats in circulation, and reduce blood pressure. Our fasting bodies change how they select which fuel to burn, improving metabolism and reducing oxidative stress.

For people with obesity, only one drug (orlistat) is currently available in the UK, and gastric surgery is a relatively rare and expensive alternative. Dietary changes remain the most common intervention used for obese people. Fasting is known to help, but former treatments were based on intermittent starving. Today's intermittent fasting regimes are easier to stick to, and are proven to help remove excess pounds melt away.

Scientists have known since the 1940s that intermittent fasting helps us lose weight, and can cut the incidence of diabetes in lab animals. Recent studies have also confirmed that restricting calorie intake could possibly reverse type 2 diabetes in some people. Researchers measured improved pancreatic function and fewer of the fatty deposits associated with insulin resistance were present in fasting subjects.

A healthy heart

In animal models, scientists have shown that intermittent fasting has some cardiovascular benefits that appear similar to exercising, such as improving blood pressure and heart rate, and lowering cholesterol. Fasting also appears to aid those with ischemic heart disease. Fasting may even protect the heart by raising levels of adiponectin, a protein that has several important roles in carbohydrate and lipid metabolism and vascular biology.

"Intermittent fasting might achieve much of the benefit seen with bariatric surgery, but without the costs, restriction on numbers and risks associated with surgery," according to lead author, James Brown. "Whether intermittent fasting can be used as a tool to prevent diabetes in those individuals at high risk or to prevent progression in those recently diagnosed with type 2 diabetes remains a tantalising notion and we are currently in preparation for clinical trials to assess the effectiveness of this form of lifestyle intervention in various patient groups."

Intermittent fasting is an increasingly popular diet plan that hit the headlines in the run up to Christmas 2012 after the release of a book on the subject. Proponents claim that in addition to weight loss, the diet can lead to longer life, and protection against disease, particularly conditions such as dementia and Alzheimer's disease.


Contact: Katie Baker
SAGE Publications

Related medicine news :

1. Contract Research Organization WCCT Global Announces Overwhelming Success of Pediatric Clinical Study Recruitment
2. More Infants Surviving With Serious Heart Defects, Study Finds
3. Stanford study examines cost-effectiveness of helicopter transport of trauma victims
4. Study Explores the Cost of Creativity
5. UK study shows potential new way to detect colorectal and other cancers
6. No Evidence That New Bird Flu Passes Between People: Study
7. Newborns Placenta May Predict Autism Risk, Study Suggests
8. 12 Ounces of Sugary Soda a Day Raises Diabetes Risk: Study
9. Porn Use Has Small Effect on Sexual Behavior, Study Finds
10. Study reveals dramatic changes in global attitudes toward domestic violence
11. Kids Concussion Recovery Varies by Symptom Severity: Study
Post Your Comments:
(Date:11/27/2015)... ... November 27, 2015 , ... ... were," said an inventor from Hillside, N.J. "Many people catch diseases simply from ... that individuals will always be protected from germs." , He developed the patent-pending ...
(Date:11/27/2015)... ... November 27, 2015 , ... ... through sharing, the 2016 Building Better Radiology Marketing Programs meeting will ... on Sunday, March 6, 2016, at Caesars Palace in Las Vegas with a ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... CBD ... Accreditation of Allied Health Education Programs (CAAHEP) awarded accreditation to its Diagnostic Medical Sonography ... CAAHEP accredited colleges, as only one of twelve colleges and universities in the state ...
(Date:11/26/2015)... ... November 26, 2015 , ... Patients at Serenity ... have come together on Thanksgiving Day to share the things that they are ... the Serenity Point YouTube channel, patients displayed what they wrote on index cards, ...
(Date:11/26/2015)... ... ... Jobs in hospital medical laboratories and in the imaging field lead the ... Aureus Medical Group . These fields, as well as travel nursing, ranked ... jobs through the company’s website, , The leading healthcare staffing agency ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 2015 ) ... "Radioimmunoassay Market by Type (Reagents & Kits, ... Clinical Diagnostic Labs), Application (Research, Clinical Diagnostics), ... report to their offering. --> ... of the "Radioimmunoassay Market by Type ...
(Date:11/25/2015)...  The total global healthcare industry is expected to grow ... Latin America has the highest projected growth at ... Japan ), is second with growth projected at 11.5%. ... healthcare expenditure. In 2013-2014, total government funded healthcare was nearly ... to 41.2% in 2013-2014. In real terms, out of pocket ...
(Date:11/25/2015)... , Nov. 25, 2015  Linden Care, LLC, ... optimizing treatment outcomes for patients suffering from chronic pain, ... for a Temporary Restraining Order (TRO) enjoining Express Scripts ... two companies. --> --> ... all of its legal options. --> ...
Breaking Medicine Technology: