Navigation Links
Forsyth launches 1-of-a-kind core service to enable rapid identification of bacterial samples
Date:1/17/2008

Today, The Forsyth Institute launched a new one-of-a-kind service for the research community. The Forsyth Microbial Identification Microarray Service (MIM) enables the rapid identification of bacterial species in clinical samples. The first service offering, Human Oral Microbe Identification Microarray (HOMIM), will focus on detection of bacterial profiles from the oral cavity. Researchers can use this service to compare bacterial associations in health vs. disease, monitor the effects of therapy on the oral ecology and perform microbial perturbation studies.

The Forsyth research team led by Drs. Bruce Paster and Floyd Dewhirst has used molecular analyses based on 16S rRNA sequencing to identify 550 oral bacterial species. Using this information, they have developed HOMIM, which allows the simultaneous detection of about 300 of the most prevalent oral bacterial species, in a single hybridization. This high throughput technology will allow the evaluation of species that cannot yet be grown in vitro. Information about the service can be found online at www.forsyth.org/mim.

HOMIM is available to researchers from academic institutions as well as private corporations. Researchers can submit DNA isolated from clinical samples and receive an online comprehensive analysis and report. Results can typically be obtained within days once processing has begun.

HOMIM provides a great tool for the oral health research community, said Philip Stashenko, President and CEO of The Forsyth Institute. The expertise of the Forsyth team is unparalleled and it can provide the scientific community with a unique opportunity to carry out global analyses of oral microbial ecology. In the future, we plan to introduce other microarrays which focus on bacteria in different body niches including the GI tract, stomach and skin.

Background

Hundreds of different species of bacteria are able to live in the human mouth, though probably not all of them are present in the same mouth at the same time. Many of these oral bacteria have not been identified because they are impossible to grow in culture in the laboratory. Using molecular techniques, the Paster and Dewhirst laboratories have developed new tools, which do not depend on traditional culturing approaches, to hunt for oral microorganisms. Since the causative agents of oral diseases are not fully known, it is likely that some, or even many, of the novel bacterial species identified by these new methods may play important roles in disease.

The oral cavity also encompasses many surfaces, including teeth, the tongue, palate, and the oral mucosa, each coated with a plethora of bacteria. Using HOMIM, the Forsyth researchers have shown that different consortia of bacteria preferentially attach to different oral surfaces.


'/>"/>

Contact: Jennifer Kelly
jkelly@forsyth.org
617-892-8602
Forsyth Institute
Source:Eurekalert

Related medicine news :

1. China Nepstar Chain Drugstore Launches Charitable Initiative to Promote Awareness of Low-income Working Womens Health Issues
2. Global Pharmaceutical Launches: Best Practices for Winning Product Launch Successes
3. Danialle Karmanos Work It Out Launches Dynamic Blog
4. Hospital Launches Landmark Project in Emergency Medicine
5. Sudden Cardiac Arrest Association Launches Two Minnesota Affiliates
6. Sudden Cardiac Arrest Association Launches Southwest Connecticut Chapter
7. Sudden Cardiac Arrest Association Launches South Florida Chapter
8. Sudden Cardiac Arrest Association Launches Long Island and Queens Chapters
9. Sudden Cardiac Arrest Association Launches Kansas City Chapter
10. Sudden Cardiac Arrest Association Launches Its First Thirteen Local Chapters/Affiliates
11. Sudden Cardiac Arrest Association Launches Iowa Affiliate
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... 2016 , ... Quality metrics are proliferating in cancer care, and are derived ... eye of the beholder, according to experts who offered insights and commentary in the ... Care. For the full issue, click here . , For the American Society ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements ... was developed to enhance the health of felines. The formula is all-natural and is ... herbs in the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the American ... Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. ... including advance care planning, healthcare costs and patient and family engagement. , AIR ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture ... said Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package ... Final Cut Pro X . Simply select a ProHand generator and drag it ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... recover from injury. Recently, he has implemented orthobiologic procedures as a method for ... is one of the first doctors to perform the treatment. Orthobiologics are substances ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Roche (SIX: RO, ROG; ... for its Elecsys BRAHMS PCT (procalcitonin) assay as a ... septic shock. With this clearance, Roche is the first ... integrated solution for sepsis risk assessment and management. ... infection and PCT levels in blood can aid clinicians ...
(Date:6/23/2016)... Capricor Therapeutics, Inc. ... company focused on the discovery, development and commercialization ... in its ongoing randomized HOPE-Duchenne clinical trial (Halt ... its 24-patient target. Capricor expects the trial to ... 2016, and to report top line data from ...
(Date:6/23/2016)... -- Bracket , a leading clinical trial technology and ... platform, Bracket eCOA (SM) 6.0, at the 52 nd ... 2016 in Philadelphia , Pennsylvania.  A demonstration ... of its kind to fully integrate with RTSM, will be ... is a flexible platform for electronic clinical outcomes assessments that ...
Breaking Medicine Technology: