Navigation Links
Forsyth launches 1-of-a-kind core service to enable rapid identification of bacterial samples
Date:1/17/2008

Today, The Forsyth Institute launched a new one-of-a-kind service for the research community. The Forsyth Microbial Identification Microarray Service (MIM) enables the rapid identification of bacterial species in clinical samples. The first service offering, Human Oral Microbe Identification Microarray (HOMIM), will focus on detection of bacterial profiles from the oral cavity. Researchers can use this service to compare bacterial associations in health vs. disease, monitor the effects of therapy on the oral ecology and perform microbial perturbation studies.

The Forsyth research team led by Drs. Bruce Paster and Floyd Dewhirst has used molecular analyses based on 16S rRNA sequencing to identify 550 oral bacterial species. Using this information, they have developed HOMIM, which allows the simultaneous detection of about 300 of the most prevalent oral bacterial species, in a single hybridization. This high throughput technology will allow the evaluation of species that cannot yet be grown in vitro. Information about the service can be found online at www.forsyth.org/mim.

HOMIM is available to researchers from academic institutions as well as private corporations. Researchers can submit DNA isolated from clinical samples and receive an online comprehensive analysis and report. Results can typically be obtained within days once processing has begun.

HOMIM provides a great tool for the oral health research community, said Philip Stashenko, President and CEO of The Forsyth Institute. The expertise of the Forsyth team is unparalleled and it can provide the scientific community with a unique opportunity to carry out global analyses of oral microbial ecology. In the future, we plan to introduce other microarrays which focus on bacteria in different body niches including the GI tract, stomach and skin.

Background

Hundreds of different species of bacteria are able to live in the human mouth, though probably not all of them are present in the same mouth at the same time. Many of these oral bacteria have not been identified because they are impossible to grow in culture in the laboratory. Using molecular techniques, the Paster and Dewhirst laboratories have developed new tools, which do not depend on traditional culturing approaches, to hunt for oral microorganisms. Since the causative agents of oral diseases are not fully known, it is likely that some, or even many, of the novel bacterial species identified by these new methods may play important roles in disease.

The oral cavity also encompasses many surfaces, including teeth, the tongue, palate, and the oral mucosa, each coated with a plethora of bacteria. Using HOMIM, the Forsyth researchers have shown that different consortia of bacteria preferentially attach to different oral surfaces.


'/>"/>

Contact: Jennifer Kelly
jkelly@forsyth.org
617-892-8602
Forsyth Institute
Source:Eurekalert

Related medicine news :

1. China Nepstar Chain Drugstore Launches Charitable Initiative to Promote Awareness of Low-income Working Womens Health Issues
2. Global Pharmaceutical Launches: Best Practices for Winning Product Launch Successes
3. Danialle Karmanos Work It Out Launches Dynamic Blog
4. Hospital Launches Landmark Project in Emergency Medicine
5. Sudden Cardiac Arrest Association Launches Two Minnesota Affiliates
6. Sudden Cardiac Arrest Association Launches Southwest Connecticut Chapter
7. Sudden Cardiac Arrest Association Launches South Florida Chapter
8. Sudden Cardiac Arrest Association Launches Long Island and Queens Chapters
9. Sudden Cardiac Arrest Association Launches Kansas City Chapter
10. Sudden Cardiac Arrest Association Launches Its First Thirteen Local Chapters/Affiliates
11. Sudden Cardiac Arrest Association Launches Iowa Affiliate
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet ... product that was developed to enhance the health of felines. The formula is all-natural ... two main herbs in the PawPaws Cat Kidney Support Supplement Soft Chews ...
(Date:6/25/2016)... ... ... The temporary closing of Bruton Memorial Library on June 21 due to a possible lice ... overlooked aspect of head lice: the parasite’s ability to live away from a human host, ... a necessary one in the event that lice have simply gotten out of control. , ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, ... Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments in ... the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, ... at his family verbally and physically. , “When something upset him, he couldn’t control his ... it. He would throw rocks at my other children and say he was going to ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and ... that call for a minimum wage raise to $12 an hour by 2020 and then ... will restore the lost value of the minimum wage, assure the wage floor does not ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... HILLS, Calif. , June 23, 2016 Any ... the many challenges of the current process. Many of them ... because of the technical difficulties and high laboratory costs involved. ... have to offer it at such a high cost that ... afford it. Dr. Parsa Zadeh , founder ...
(Date:6/23/2016)... 23, 2016 Capricor Therapeutics, ... a biotechnology company focused on the discovery, development ... patient enrollment in its ongoing randomized HOPE-Duchenne clinical ... 50% of its 24-patient target. Capricor expects the ... quarter of 2016, and to report top line ...
(Date:6/23/2016)... 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new affiliate with operations headquartered ... Latin America . ... ... ... ...
Breaking Medicine Technology: