Navigation Links
Forsyth launches 1-of-a-kind core service to enable rapid identification of bacterial samples
Date:1/17/2008

Today, The Forsyth Institute launched a new one-of-a-kind service for the research community. The Forsyth Microbial Identification Microarray Service (MIM) enables the rapid identification of bacterial species in clinical samples. The first service offering, Human Oral Microbe Identification Microarray (HOMIM), will focus on detection of bacterial profiles from the oral cavity. Researchers can use this service to compare bacterial associations in health vs. disease, monitor the effects of therapy on the oral ecology and perform microbial perturbation studies.

The Forsyth research team led by Drs. Bruce Paster and Floyd Dewhirst has used molecular analyses based on 16S rRNA sequencing to identify 550 oral bacterial species. Using this information, they have developed HOMIM, which allows the simultaneous detection of about 300 of the most prevalent oral bacterial species, in a single hybridization. This high throughput technology will allow the evaluation of species that cannot yet be grown in vitro. Information about the service can be found online at www.forsyth.org/mim.

HOMIM is available to researchers from academic institutions as well as private corporations. Researchers can submit DNA isolated from clinical samples and receive an online comprehensive analysis and report. Results can typically be obtained within days once processing has begun.

HOMIM provides a great tool for the oral health research community, said Philip Stashenko, President and CEO of The Forsyth Institute. The expertise of the Forsyth team is unparalleled and it can provide the scientific community with a unique opportunity to carry out global analyses of oral microbial ecology. In the future, we plan to introduce other microarrays which focus on bacteria in different body niches including the GI tract, stomach and skin.

Background

Hundreds of different species of bacteria are able to live in the human mouth, though probably not all of them are present in the same mouth at the same time. Many of these oral bacteria have not been identified because they are impossible to grow in culture in the laboratory. Using molecular techniques, the Paster and Dewhirst laboratories have developed new tools, which do not depend on traditional culturing approaches, to hunt for oral microorganisms. Since the causative agents of oral diseases are not fully known, it is likely that some, or even many, of the novel bacterial species identified by these new methods may play important roles in disease.

The oral cavity also encompasses many surfaces, including teeth, the tongue, palate, and the oral mucosa, each coated with a plethora of bacteria. Using HOMIM, the Forsyth researchers have shown that different consortia of bacteria preferentially attach to different oral surfaces.


'/>"/>

Contact: Jennifer Kelly
jkelly@forsyth.org
617-892-8602
Forsyth Institute
Source:Eurekalert

Related medicine news :

1. China Nepstar Chain Drugstore Launches Charitable Initiative to Promote Awareness of Low-income Working Womens Health Issues
2. Global Pharmaceutical Launches: Best Practices for Winning Product Launch Successes
3. Danialle Karmanos Work It Out Launches Dynamic Blog
4. Hospital Launches Landmark Project in Emergency Medicine
5. Sudden Cardiac Arrest Association Launches Two Minnesota Affiliates
6. Sudden Cardiac Arrest Association Launches Southwest Connecticut Chapter
7. Sudden Cardiac Arrest Association Launches South Florida Chapter
8. Sudden Cardiac Arrest Association Launches Long Island and Queens Chapters
9. Sudden Cardiac Arrest Association Launches Kansas City Chapter
10. Sudden Cardiac Arrest Association Launches Its First Thirteen Local Chapters/Affiliates
11. Sudden Cardiac Arrest Association Launches Iowa Affiliate
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2017)... , ... June 23, 2017 , ... Ulster University, Magee ... 2017 from 9 am to 3 pm to present to graduate students exciting new ... is an original curriculum project led by The Health Improvement Service of the Western ...
(Date:6/23/2017)... The Woodlands, TX (PRWEB) , ... June 23, ... ... provides families and business owners in the Houston area with access to asset ... Foundation for a regional charity event aimed at improving the lives of children ...
(Date:6/22/2017)... ... 2017 , ... Children’s National Health System has ... launch a Rheumatic Heart Disease Center, with the goal of developing innovative strategies ... (RHD) in high-risk, financially disadvantaged countries and low-income communities across the United States. ...
(Date:6/22/2017)... California (PRWEB) , ... June 23, 2017 , ... ... forces in the fight against hunger on June 21, 2017, at the Emeryville ... fight food insecurity and malnutrition around the world. , Rise Against Hunger (formerly ...
(Date:6/20/2017)... ... 20, 2017 , ... Caduceus International Publishing (CIP), a leading ... new online course entitled Personal & Community Health for the Fall ... achieving optimal well-being and teaches students how to apply them in their everyday ...
Breaking Medicine News(10 mins):
(Date:6/7/2017)... 2017  Diplomat Specialty Infusion Group, a brand of Diplomat Pharmacy, ... Iowa location. The ... features an ISO 7 cleanroom—the standard needed to compound intravenous (IV) ... level of pollutants. "Our new ... better serve our Iowa patients," said ...
(Date:6/2/2017)...  NxStage Medical, Inc. (Nasdaq:  NXTM), a leading medical technology company ... demonstrating positive biochemical outcomes related to more frequent hemodialysis ... will be presented at the ERA-EDTA Congress being held ... . The research was conducted by ... Europe (KIHDNEy) Cohort team ...
(Date:5/30/2017)... AVIV, Israel , May 30, 2017 ... stage pharmaceutical Company specializing in the development of ... will present a company overview at three upcoming ... The 7th Annual LD Micro Invitational: ... Date:                     ...
Breaking Medicine Technology: