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Former substance abusers rarely relapse after organ transplantation
Date:2/4/2008

amount of data available, relapse risk factors could only be assessed for alcohol use. While demographics and pre-transplant characteristics showed little correlation with relapse, poor social support, family alcohol history and pre-transplant abstinence of less than 6 months showed small but significant associations with relapse.

Future research should focus on improving the prediction of risk for substance abuse relapse, and on testing interventions to promote continued abstinence post-transplant, the authors conclude.

An accompanying editorial by Michael Lucey and colleagues of the University of Wisconsin Medical School et al. congratulates Dew et al for their outstanding effort to analyze alcohol and drug use after transplantation, while noting that, for the addiction specialist, the persistence of sobriety after transplantation is surprising and unexplained.

They call for future studies with prospective designs that also separate study personnel from transplant personnel to better identify alcohol and drug relapse, since patients may otherwise conceal their behavior. Further, they conclude based on Dew et als findings, we need future studies that confront the issue of the suitability for transplantation of patients with duration of abstinence shorter than six months.


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Contact: Amy Molnar
amolnar@wiley.com
Wiley-Blackwell
Source:Eurekalert

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