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Forest Laboratories, Inc. Announces FDA Approval of Lexapro(R) for the Treatment of Major Depressive Disorder in Adolescents
Date:3/20/2009

st year, according to a recent national survey conducted by the Substance Abuse and Mental Health Services Administration. Adolescent depression is characterized by persistent sadness or irritability or loss of interest in usual activities. For adolescents who suffer from depression, talk therapy and medication can play an important role in the management of their illness. Patients on antidepressant treatment should also be closely monitored by healthcare providers, family members, and other caregivers.

About Lexapro

Lexapro is indicated for the acute and maintenance treatment of MDD in adults and adolescents (aged 12-17) and for acute treatment of Generalized Anxiety Disorder (GAD) in adults. Lexapro is thought to work by helping to restore the brain's chemical balance. It is believed to increase the availability of serotonin, a substance in the brain thought to influence mood. Since its launch in 2002, Lexapro has been prescribed to more than 18 million patients in the U.S.

IMPORTANT SAFETY INFORMATION

Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of Lexapro or any other antidepressant in a child, adolescent or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicid
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SOURCE Forest Laboratories, Inc.
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