Navigation Links
Foreign multidrug resistant bacteria contained in Toronto hospital
Date:12/11/2012

CHICAGO (December 11, 2012) As the prevalence of antibiotic-resistant infections continue to rise around the world, a hospital in Canada detected the presence of New Delhi Metallo--lactamase-1-Producing Klebsiella pneumoniae (NDM1-Kp), a multidrug resistant bacteria that is resistant to carbapenems, one of the last lines of antibiotics. The retrospective report, featured in the January issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America, analyzes risk factors and infection control strategies taken to prevent the spread of NDM1-Kp.

NDM1-Kp is common in other parts of the world such as the Indian subcontinent, but rare in North America except for imported cases from patients previously hospitalized in endemic regions.

Between January 2011 and March 2012, seven patients at a tertiary care teaching hospital in Toronto acquired NDM1-Kp from two index patients. Risk factors for acquisition were a history of prior use of certain antibiotics, and transmission likely occurred through direct contact. Four of the seven were roommates with an affected patient, two were on the same ward, and one was admitted to a room immediately following the discharge of an infected patient. The environmental sources of transmission highlight the importance of maintaining meticulous cleaning, hand hygiene, and disinfection standards in prevention and containment.

"The spread of the NDM1-Kp is an emerging public health threat, as increased globalization may result in a higher burden of these bacteria in Canada and other countries than previously recognized," said lead researcher Christopher F. Lowe, MD. "Preventing the spread of this organism in hospitals is critical given the lack of effective antibiotics against NDM1-Kp."

When a patient was identified with NDM1-Kp at the hospital, they were placed on contact precautions for the duration of their admission, as recommended by the CDC and Public Health Agency of Canada. At the Toronto hospital, contacts such as roommates or ward mates were screened 3 times over a 2 week period to see if transmission had occurred. During the screening period, the patients were also placed into contact precautions and private rooms until all three screenings were negative. Unfortunately, staff discovered that several contacts with negative screens subsequently became positive for NDM1-Kp weeks later.

Challenges in fighting the spread of NDM1-Kp include contacts who acquire the bacteria, but may initially have a low concentration of organisms and avoid detection, as well as the lack of an established gold standard to detect carbapenem-resistant organisms, which may have contributed to the negative screens. Although the isolation of NDM1-producing bacteria is currently a rare occurrence in healthcare settings, this cluster indicates the prevalence of these organisms is increasing in nonendemic regions, and prompt initiation of infection prevention and control practices is essential to prevent transmission.


'/>"/>

Contact: Kate Enos
kenos@gymr.com
202-745-5071
Society for Healthcare Epidemiology of America
Source:Eurekalert

Related medicine news :

1. Kinase test may yield big gains for drug-resistant cancers
2. New drug strategy attacks resistant leukemia and lymphoma
3. Einstein awarded $6 million grant to develop new TB vaccine against drug-resistant strains
4. New Medicine Might Fight Drug-Resistant TB, Study Says
5. Antibiotic-Resistant Gonorrhea Spreading: WHO
6. Rare Drug-Resistant Bacteria Spotted in U.S. Hospital
7. Scientists develop new strategy to overcome drug-resistant childhood cancer
8. Abuse-Resistant Oxycontin May Be Driving Addicts to Heroin
9. A new route for tackling treatment-resistant prostate cancer
10. Computational analysis identifies drugs to treat drug-resistant breast cancer
11. Treating drug resistant cancer through targeted inhibition of sphingosine kinase
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/17/2017)... ... February 17, 2017 , ... Smiles by Seese is a comprehensive ... Dr. Brian Seese leads the practice as a skilled and highly credentialed dentist who ... by Seese serves patients of all ages with excellence in general, restorative, and ...
(Date:2/17/2017)... ... February 17, 2017 , ... ... FDAnews Webinar**, Feb. 22, 2017 — 1:30 p.m. – 2:30 p.m. ET, ... should be asking before selecting an FDA approval pathway? , How should ...
(Date:2/17/2017)... ... February 17, 2017 , ... ... 2017 season , Trinity Health and the U.S. Soccer Foundation announced today that ... in underserved communities. Soccer for Success, the Foundation’s soccer mentoring program, teaches kids ...
(Date:2/17/2017)... ... 17, 2017 , ... Like most hospitals across the nation, Onslow Memorial Hospital ... the Hospital Readmission Reduction Program (HRRP), the return of a patient to the hospital ... the nation. While many providers are struggling to leverage limited resources and technology, Onslow ...
(Date:2/16/2017)... (PRWEB) , ... February 17, 2017 , ... ... their experience can last long after their final treatments. Physician researchers at ... neuro-emotional technique (NET), a mind-body therapy, for efficacy in reducing symptoms of traumatic ...
Breaking Medicine News(10 mins):
(Date:2/16/2017)... 2017  Express Scripts (NASDAQ: ESRX ) was recognized ... Companies within the Health Care: Pharmacy and Other Services category. ... World,s Most Admired Companies," said Tim Wentworth , CEO and ... passion of our 26,000 employees to make medicine more affordable and ... ...
(Date:2/16/2017)...  Prescription pain medications provided by "physicians in the ... long-term opioid use to take hold," according to a ... of The New England Journal of Medicine ... in acute pain than in almost any other medical ... of the American College of Emergency Physicians. "The challenge ...
(Date:2/16/2017)... , Feb. 16, 2017   Spectralink ... solutions for the healthcare, retail, manufacturing and hospitality ... on the performance and symbology support features of ... a dual-mode camera/barcode scanner. The study, conducted by ... the PIVOT:SC to two phones with dedicated hardware ...
Breaking Medicine Technology: