Navigation Links
Foreign multidrug resistant bacteria contained in Toronto hospital
Date:12/11/2012

CHICAGO (December 11, 2012) As the prevalence of antibiotic-resistant infections continue to rise around the world, a hospital in Canada detected the presence of New Delhi Metallo--lactamase-1-Producing Klebsiella pneumoniae (NDM1-Kp), a multidrug resistant bacteria that is resistant to carbapenems, one of the last lines of antibiotics. The retrospective report, featured in the January issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America, analyzes risk factors and infection control strategies taken to prevent the spread of NDM1-Kp.

NDM1-Kp is common in other parts of the world such as the Indian subcontinent, but rare in North America except for imported cases from patients previously hospitalized in endemic regions.

Between January 2011 and March 2012, seven patients at a tertiary care teaching hospital in Toronto acquired NDM1-Kp from two index patients. Risk factors for acquisition were a history of prior use of certain antibiotics, and transmission likely occurred through direct contact. Four of the seven were roommates with an affected patient, two were on the same ward, and one was admitted to a room immediately following the discharge of an infected patient. The environmental sources of transmission highlight the importance of maintaining meticulous cleaning, hand hygiene, and disinfection standards in prevention and containment.

"The spread of the NDM1-Kp is an emerging public health threat, as increased globalization may result in a higher burden of these bacteria in Canada and other countries than previously recognized," said lead researcher Christopher F. Lowe, MD. "Preventing the spread of this organism in hospitals is critical given the lack of effective antibiotics against NDM1-Kp."

When a patient was identified with NDM1-Kp at the hospital, they were placed on contact precautions for the duration of their admission, as recommended by the CDC and Public Health Agency of Canada. At the Toronto hospital, contacts such as roommates or ward mates were screened 3 times over a 2 week period to see if transmission had occurred. During the screening period, the patients were also placed into contact precautions and private rooms until all three screenings were negative. Unfortunately, staff discovered that several contacts with negative screens subsequently became positive for NDM1-Kp weeks later.

Challenges in fighting the spread of NDM1-Kp include contacts who acquire the bacteria, but may initially have a low concentration of organisms and avoid detection, as well as the lack of an established gold standard to detect carbapenem-resistant organisms, which may have contributed to the negative screens. Although the isolation of NDM1-producing bacteria is currently a rare occurrence in healthcare settings, this cluster indicates the prevalence of these organisms is increasing in nonendemic regions, and prompt initiation of infection prevention and control practices is essential to prevent transmission.


'/>"/>

Contact: Kate Enos
kenos@gymr.com
202-745-5071
Society for Healthcare Epidemiology of America
Source:Eurekalert

Related medicine news :

1. Kinase test may yield big gains for drug-resistant cancers
2. New drug strategy attacks resistant leukemia and lymphoma
3. Einstein awarded $6 million grant to develop new TB vaccine against drug-resistant strains
4. New Medicine Might Fight Drug-Resistant TB, Study Says
5. Antibiotic-Resistant Gonorrhea Spreading: WHO
6. Rare Drug-Resistant Bacteria Spotted in U.S. Hospital
7. Scientists develop new strategy to overcome drug-resistant childhood cancer
8. Abuse-Resistant Oxycontin May Be Driving Addicts to Heroin
9. A new route for tackling treatment-resistant prostate cancer
10. Computational analysis identifies drugs to treat drug-resistant breast cancer
11. Treating drug resistant cancer through targeted inhibition of sphingosine kinase
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... Hagerstown, MD (PRWEB) , ... January 20, 2017 , ... ... people to donate items they no longer use or need, from clothes to couches ... up any unwanted items and take them to the nearest Goodwill donation center through ...
(Date:1/20/2017)... ... January 20, 2017 , ... Lice Troopers, the lice removal company based ... school-aged children since the holiday season. , “It happens every year around this ... hugs and taking photos, which is the head-to-head gateway that lice need to spread.” ...
(Date:1/20/2017)... ... 20, 2017 , ... Vitamin Well has launched two new ... have been produced in collaboration with Zlatan Ibrahimovic and have been developed to ... a successful launch in Sweden last year, the next generation sports drinks VW+001 ...
(Date:1/20/2017)... (PRWEB) , ... January 20, 2017 , ... ... vPEP ® Oscillating Positive Expiratory Pressure (OPEP) device, was featured in a study ... Doug Pursley, MEd, RRT-ACCS, FAARC, “Analysis of Three Oscillating Positive Expiratory Pressure ...
(Date:1/20/2017)... (PRWEB) , ... January 20, 2017 , ... “God's Miracle ... Against All Odds” is the creation of published author, Keith C. A. Tucker, son ... the Christian Fellowship World Outreach pastured by Reverend Mark Hardy , “While sitting up ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... , Jan. 19, 2017 Report Details ... ... for Leading Companies – our new study reveals trends, ... issues and events affecting the Alzheimer,s disease therapeutics and ... answer these key questions: - How is the Alzheimer,s ...
(Date:1/19/2017)... -- Stealth BioTherapeutics Inc. ( Stealth ), a clinical-stage biopharmaceutical ... new additions to its senior leadership team: W. ... Daniel Geffken as interim Chief Financial Officer. ... Pharm.D. has been promoted to Chief Clinical Development Officer. ... and Daniel to our management team, as both will ...
(Date:1/19/2017)... , Jan. 19, 2017 Accuray Incorporated ... CyberKnife® and TomoTherapy® Systems continue to set the bar ... the highest composite overall user satisfaction rating among radiation ... Q4 2016 MD Buyline Market Intelligence Briefing™. The most ... highest composite ratings among industry peers for 11 of ...
Breaking Medicine Technology: