Navigation Links
For the fruit fly, everything changes after sex
Date:12/10/2007

This release is also available in German.

IMP Director Barry Dickson and his group are interested in the genetic basis of innate behaviour. They focus on the reproductive behaviour of the fruit fly Drosophila melanogaster. Two years ago, the team was able to identify the fruitless gene as a key regulator of mating behaviour.

For 20 years, scientists have been trying to identify another molecular switch which changes the behaviour of female insects after mating. It makes them lose interest in further sexual contact and start laying eggs. Mosquitoes, once fertilized, look out for a meal of blood and may transmit the malaria parasite along the way.

The trigger for the behavioral switch is a factor present in the seminal fluid of male insects. This sex peptide (SP), as it is called in Drosophila, has been known to scientists for quite a while. Nilay Yapici, a PhD student in Barry Dicksons team, has now identified the receptor (SPR) responsible for the effect of SP and thus revealed the underlying molecular mechanism. She also showed that the gene for SPR is active in the reproductive organs as well as the brain of the flies.

To get this far, it took two years of painstaking work and a scientific tool which was developed over the past few years by the Dickson group. This Drosophila RNAi Library is a collection of 22,000 fly strains and has recently been made available to researchers worldwide. Due to this collection, it is now possible to switch off any chosen gene in the fly. By doing so, neurobiologists are able to identify genes that influence behaviour.

Nilay Yapici studied 22,000 female flies and observed how they behaved after mating. In 130 cases, she found flies which continued to mate and laid very few or no eggs. Further evaluation of these genes and subsequent experiments with cell cultures led to the identification of the long-sought receptor, SPR. By activating or disrupting SPR in specific neurons, the receptor could be localized in the central nervous system of the fly.

Apart from the benefit to basic research, the discovery might offer new approaches for controlling the reproductive or host-seeking behaviours of various agricultural pests and human disease carriers. The molecular mechanism has remained remarkably stable in the course of evolution and SPR-like receptors can be found in many insect species. Ms. Yapici thinks that It might be possible to develop a substance that blocks the receptor SPR. This inhibitor would work as a kind of birth control pill: female insects would continue to mate but would not lay eggs.


'/>"/>

Contact: Heidemarie Hurtl
hurtl@imp.ac.at
43-179-730-3625
Research Institute of Molecular Pathology
Source:Eurekalert

Related medicine news :

1. Coloring Compound in Fruits, Veggies May Cut Colon Cancer Risk
2. Scientists detect presence of marburg virus in african fruit bats
3. Pollen, Fruits, Veggies Help Trigger Oral Allergy Syndrome
4. Get Your Fruits & Veggies: CDC
5. Fruity vegetables and fish reduce asthma and allergies
6. P.A.C.K. Week Declared in Support of Fruits & Veggies-More Matters Month
7. Produce for Better Health Foundation Releases Statement on Study Saying Fruit & Vegetable Consumption Not Strongly Associated With Colon Cancer Risk
8. Fruits, Veggies Wont Lower Colon Cancer Risk
9. Fruit and vegetables health
10. Abbott Launches Fruitified(TM) ZonePerfect(R) All-Natural Nutrition Bars
11. Fish, Fruits, Veggies May Cut Dementia Risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... QUEENS, N.Y (PRWEB) , ... October 13, 2017 , ... ... recently became a member of ElderCounsel, a national organization of elder law and special ... constantly changing laws and rules. It also provides a forum to network with elder ...
(Date:10/13/2017)... ... ... The Visiting Nurse Association (VNA) of Somerset Hills is proud to host ... items from across the nation, this holiday-themed event will raise funds and awareness for ... The boutique will be open Saturday, November 4 (10:00 a.m. – 5:00 p.m.) ...
(Date:10/13/2017)... ... 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of ... popular and least understood books in the Holy Scriptures, Revelation. The Book of Revelation ... scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl Hawkins ...
(Date:10/13/2017)... ... ... “The Journey: From the Mountains to the Mission Field”: the story of a missionary ... Journey: From the Mountains to the Mission Field” is the creation of published author, ... ages and currently teaches a class of ladies at her church, which she has ...
(Date:10/12/2017)... San Francisco, CA (PRWEB) , ... October 12, ... ... and Dr. Cheng, are now treating sleep apnea using cutting-edge Oventus ... sleep apnea, a serious sleep disorder characterized by frequent cessation in breathing. Oral ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)...   Montrium , an industry leader in ... IQPC Trial Master Files & Inspection Readiness Conference ... Clinical Services has selected eTMF Connect ... EastHORN, a leading European contract research organization (CRO), ... to enable greater collaboration with sponsors, improve compliance ...
(Date:9/22/2017)... 22, 2017  As the latest Obamacare repeal effort ... Cassidy (R-LA) and Lindsey Graham (R-SC) ... medical device industry is in an odd place.  The ... 2.3% excise tax on medical device sales passed along ... covered patients, increased visits and hospital customers with the ...
(Date:9/19/2017)... Sept. 19, 2017   ZirMed Inc ., a recognized ... announced that it has been ranked #1 by its users ... Rankings 2017 User Survey. ZirMed was recognized as the ... hospitals and medical centers over 200 beds and holds one ... technology user survey history. ...
Breaking Medicine Technology: