Navigation Links
For some women, preventive mastectomies pay off
Date:9/3/2010

SAN ANTONIO, TX (Sept. 3) A long-term study of women with a genetic predisposition for breast or ovarian cancer showed that those who elected major preventive surgeries had a significantly reduced risk of those cancers.

The study, published Sept. 1 in the Journal of the American Medical Association, confirms the view of one of its researchers, Gail Tomlinson, M.D., Ph.D., interim director of the Greehey Children's Cancer Research Institute at The University of Texas Health Science Center at San Antonio.

Dr. Tomlinson said that for women with certain genetic mutations, risk-reducing mastectomies and removal of the fallopian tubes and ovaries can be worth it for the women and their families.

"We have believed this for 15 years," said Dr. Tomlinson, "but it's been so controversial removing organs for cancer risk."

The idea can be jarring unless one considers that the women with the specific genetic mutations, BRCA1 and BRCA2, are seeing people in their family suffering from these cancers one after another, Dr. Tomlinson said. She noted that often these are women with young families and careers to worry about, and the worry about dying from cancer at an early age because of familial predisposition can be overwhelming.

"This is a compromise women are willing to accept and their husbands are willing to accept, because the whole family worries about whether the women are going to get breast cancer," Dr. Tomlinson said.

The study does not address quality of life issues after such radical surgery, and Dr. Tomlinson said that is a concern that must be weighed by the women and their families. But the relief of having that risk taken away is hard to measure.

The study also supports Dr. Tomlinson's effort to build a genetic program at the Cancer Therapy & Research Center at the UT Health Science Center, she said, noting that the first steps have been taken with the hiring of a genetic counselor to work with families at risk for cancer. It's a program that will have benefits across the generations, she said, helping people identify and deal with hereditary risks associated with more than just those two cancers.

In addition to breast and ovarian cancer, she said, "certain types of thyroid and kidney cancer run in families and early intervention can be lifesaving."

The study followed nearly 2,500 women at higher risk for breast or ovarian cancer because of two genetic mutations between 1974 and 2008 at 22 centers in Europe and North America.

In 247 women who chose risk-reducing mastectomies, no breast cancers were diagnosed, while one in 13 of the 1,372 who did not have the surgery were diagnosed with breast cancer. Women who had their ovaries and fallopian tubes removed had a lower risk of ovarian cancer, including those with prior breast cancer, and a lower risk of dying from either cancer.


'/>"/>

Contact: Elizabeth Allen
allenea@uthscsa.edu
210-450-2020
University of Texas Health Science Center at San Antonio
Source:Eurekalert

Related medicine news :

1. Women, Diabetics Fall Fast Into Medicare Doughnut Hole
2. ICRW Says to Stop Violence against Women, Aim National Policies at Men
3. For Younger Women, Mammograms Not Too Effective: Study
4. Women, minorities more likely to see doctor of choice in emergency room
5. Pet Dental Month Prime Time To Schedule Preventive Annual Cleaning For Pets
6. Preventive behaviors limited household transmission of H1N1 influenza during initial outbreak
7. Preventive Mastectomy May Not Lower Risks
8. Device to revolutionize preventive blood clot care after joint replacement surgery
9. U.S. Preventive Medicine Helps Participants of the State of Nevada Public Employees' Benefits Program (PEBP) Become Healthier
10. Lab Industry Likely to Benefit from Expanded Preventive Testing Under New Health Care Law
11. Summit Health, U.S. Preventive Medicine Agree to Continue Worksite Screening Partnership
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2017)... (PRWEB) , ... August 21, 2017 , ... San Diego ... ) health care reform plan, has announced his candidacy for the 52nd Congressional District ... and shared in America’s Promise. Coming to this country at age eleven after suffering ...
(Date:8/21/2017)... ... August 21, 2017 , ... The Industrial Designers Society of America (IDSA) ... Ceremony and Gala on Aug. 19, 2017 in Atlanta, GA—revealing which 25 designs won ... and rigorous design competitions. See all the winners at http://www.idsa.org/awards/idea/gallery . , “I ...
(Date:8/20/2017)... ... August 20, 2017 , ... HIPAA Solutions, ... System has assisted multiple clients in successfully passing audits such as Office ... Level 2 (AICPA SOC Level 2), and State Data Use Agreement Audits. ...
(Date:8/20/2017)... ... ... Are you an adult with gluten intolerance or Celiac disease living with another ... in a research study that focuses on family interactions when dealing with dietary restrictions. ... of adults who have gluten sensitivities who cohabitate with other adults who may or ...
(Date:8/19/2017)... ... August 18, 2017 , ... Western University of Health Sciences will host a ... University’s new Center for Innovation on Wednesday, September 6, 2017. , The symposium will ... followed by a technology exhibition from 1 to 3 p.m. showcasing virtual reality education ...
Breaking Medicine News(10 mins):
(Date:8/8/2017)... Second-quarter 2017 revenues of $876 million and ... operations Second-quarter 2017 Branded ... Second-quarter 2017 Sterile Injectables ... Second-quarter 2017 adjusted diluted earnings per ... $0.93 Second-quarter 2017 reported ...
(Date:8/7/2017)... Pharmacy, Inc. (NYSE: DPLO), the nation,s largest independent specialty pharmacy, ...  All comparisons, unless otherwise noted, are to the quarter ended ... Second Quarter 2017 Highlights include: Revenue ... 3.5% Total prescriptions dispensed of 220,000, compared ... 7.6% Gross profit per prescription dispensed ...
(Date:8/3/2017)... SAN DIEGO , Aug. 3, 2017  Opioid ... crippling diseases driving up healthcare costs and threatening outcomes, ... the lab supply and IVD industry that support them, ... health care market researcher said that drugs of abuse, ... vendors and sessions at the organization,s 69th meeting in ...
Breaking Medicine Technology: