Navigation Links
For lung transplant, researchers surprised to learn bigger appears to be better
Date:7/31/2013

icted total lung capacity for the recipient. Merlo's research found that double lung transplant recipients who received lungs with an average ratio of 1.3 were 30 percent less likely to die in the first year.

The research, led by Michael Eberlein, M.D., Ph.D., a former Johns Hopkins medical resident and fellow, was done by analyzing data from 4,520 double lung transplants and 2,477 single lung transplants performed between May 2005 and April 2010 in the United States. The findings were clearer about the benefits of larger lungs in double lung transplants than in single ones, though oversized lungs did convey some survival benefit in those cases as well, they found.

"Size is a more powerful predictor of survival than we ever thought," says Ashish S. Shah, M.D., surgical director of lung transplantation at The Johns Hopkins Hospital and another of the study's authors. "Fears of oversized lungs appear to be unfounded. We hope this research dispels some myths."

In lung transplant, the sickest patients move to the top of the list. Once an adult patient is atop the list, height and gender (along with blood type) are used to determine whether those lungs are suitable for that patient. Merlo and Shah say it might be better to build in a calculation for predicted lung capacity. That way, oversized lungs could be offered to patients instead of smaller lungs that may not work as well.

Lungs can be too large, they caution. If lungs are beyond a certain size, surgeons could have trouble closing the chest cavity, the lungs could be too compressed and collapse or could weigh too heavily on the heart, causing low blood pressure and other problems.

Currently, children under 12 cannot receive adult lungs and adults cannot receive lungs from pediatric donors. Shah, an associate professor of surgery at Johns Hopkins, says the findings suggest that there may be some benefit to removing age from the equation altogether when allocating lungs, p
'/>"/>

Contact: Stephanie Desmon
sdesmon1@jhmi.edu
410-955-8665
Johns Hopkins Medicine
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. HIV No Barrier to Getting Liver Transplant, Study Finds
2. New grant empowers young researchers to find a cure for pancreatic cancer
3. HealthCarePoint and ViS Research Streamline Sharing of Qualifications by Medical Researchers
4. Researchers identify genetic mutation linked to congenital heart disease
5. Researchers find potential new target to treat malignant pleural mesothelioma
6. Researchers target HER1 receptor for peptide cancer vaccine, therapeutic agents
7. University of Hawaii Cancer Center researchers report
8. Mount Sinai researchers discover mechanism behind development of autoimmune hepatitis
9. Dead gene comes to life, puts chill on inflammation, Stanford researchers find
10. Researchers identify 146 contemporary medical practices offering no net benefits
11. Protein complex linked to cancer growth may also help fight tumors, Moffitt researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/31/2015)... , ... August 31, 2015 , ... ... Surgery Program at Monmouth, was one of the first doctors in the area ... of this new approach have been impressive: faster recovery, decreased immediate and long-term ...
(Date:8/31/2015)... (PRWEB) , ... August 31, 2015 , ... With the FCPX LUT Soft pack from ... LUT is a Lookup Table that contains a mathematical formula for modifying an image. The ... comes with 60 soft CUBE LUT files. , FCPX LUT Soft requires Final Cut ...
(Date:8/31/2015)... ... August 31, 2015 , ... Diablo ... announced today that it has officially launched a new website and company identity ... brand refresh are more closely aligned with the company’s strategic vision for growth ...
(Date:8/31/2015)... ... August 31, 2015 , ... Dad Phil, son ... ceremony on Aug. 26, generously hosted by the Collinsville Chamber of Commerce, but ... National Call Center and website since Aug. 17. , The Greens have operated ...
(Date:8/31/2015)... (PRWEB) , ... August 31, 2015 , ... ... provider of the CME-certified annual Chemotherapy Foundation Symposium: Innovative Cancer Therapy for ... be held Nov. 4 – 6 in New York City. The annual legacy ...
Breaking Medicine News(10 mins):Health News:NJ Top Docs Presents, Dr. David L. Chalnick! 2Health News:NJ Top Docs Presents, Dr. David L. Chalnick! 3Health News:NJ Top Docs Presents, Dr. David L. Chalnick! 4Health News:Pixel Film Studios, FCPX Plugin Developer, Releases FCPX LUT Soft 2Health News:Diablo Publications Launches New Company Website 2Health News:Diablo Publications Launches New Company Website 3Health News:Ribbon Cutting Launches AdvantaClean of Madison County 2Health News:Physicians’ Education Resource® Seeks Abstracts for the Upcoming Chemotherapy Foundation Symposium: Innovative Cancer Therapy for Tomorrow® 2Health News:Physicians’ Education Resource® Seeks Abstracts for the Upcoming Chemotherapy Foundation Symposium: Innovative Cancer Therapy for Tomorrow® 3Health News:Physicians’ Education Resource® Seeks Abstracts for the Upcoming Chemotherapy Foundation Symposium: Innovative Cancer Therapy for Tomorrow® 4
... Almac ... on academically based clinical trials. , ... (PRWEB) May 5, 2010 -- The site in Durham which recently doubled capacity ... part of the Duke Clinical Research Institute from 1990-2000 with all of the studies handled ...
... whose spouse has dementia are at significantly higher risk ... adults whose spouse never develops dementia. This is ... the Journal of the American Geriatrics Society . ... natural marital obligation, and spousal caregivers often report positive ...
... ,numerous deficiencies, at plant , TUESDAY, May 4 ... in ingredients used to make the liquid cold and ... drug giant McNeil Consumer Healthcare, according to a report ... Administration. , Last Friday, McNeil initiated a voluntary recall ...
... ... quinoa, and teff provide important nutrients for the gluten-free diet, but Carol Fenster bakes with ... pastries. To celebrate May as National Celiac Awareness month, she offers a free sorghum-based cookbook, ... . , ...
... stroke , TUESDAY, May 4 (HealthDay News) -- Being ... attack or stroke in men older than 45, a new ... ages 45 to 69, who enrolled in the California Men,s ... followed until Dec. 31, 2007. , During the follow-up, there ...
... - Reasonable worst-case scenarios for global warming could lead ... to research findings from Purdue University and the University ... first time have calculated the highest tolerable "wet-bulb" temperature ... the first time in human history in future climate ...
Cached Medicine News:Health News:Almac's North Carolina Facility Continues Growth in Academically Based Clinical Trials 2Health News:Spouses of dementia sufferers have a 6-fold increased risk of dementia onset 2Health News:FDA Found Bacteria in Ingredients for Recalled Tylenol, Benadryl 2Health News:Carol Fenster Offers Tips for Gluten-Free Cooking with Sorghum: May is National Celiac Awareness Month 2Health News:Researchers find future temperatures could exceed livable limits 2Health News:Researchers find future temperatures could exceed livable limits 3
(Date:8/31/2015)... Aug. 31, 2015 The Wolf Administration today ... Pennsylvania State Police and local ... naloxone. Heroin and opioid overdose are the ... , killing more individuals than those involved in ... died from a drug overdose. " ...
(Date:8/31/2015)... Aug. 31, 2015  Dipexium Pharmaceuticals, Inc. (NASDAQ: ... development and commercialization of Locilex® (pexiganan cream 0.8%), a ... to participate in four investor conferences in September. ... the Sidoti & Company, LLC Emerging Growth Conference ... David P. Luci , President & Chief Executive Officer, ...
(Date:8/31/2015)... , August 31, 2015 ... BOLT, OTCQX: BLGTY) ("BioLight" or the "Company"), a ... innovations in ophthalmology and cancer diagnostics, today announced ... MCTC), has identified several new genetic markers with ... in patients treated with bisphosphonate drugs and was ...
Breaking Medicine Technology:Departments of Drug & Alcohol Programs and Health Announce Report 289 Pennsylvanian Lives Saved by Naloxone 2Departments of Drug & Alcohol Programs and Health Announce Report 289 Pennsylvanian Lives Saved by Naloxone 3Dipexium Pharmaceuticals Announces Participation in Four Investor Conferences in September 2Dipexium Pharmaceuticals Announces Participation in Four Investor Conferences in September 3BioLight Reports Positive Clinical Study Results for Identifying New Genetic Markers to Predict Risk of Developing BRONJ 2BioLight Reports Positive Clinical Study Results for Identifying New Genetic Markers to Predict Risk of Developing BRONJ 3BioLight Reports Positive Clinical Study Results for Identifying New Genetic Markers to Predict Risk of Developing BRONJ 4
... June 21, 2010 ReportsandReports announces it Will,Carry Cardiovascular Devices Market ... , , ... http://www.reportsandreports.com/market-reports/netherlands-cardiovascular-de ,vices-market-outlook-to-2016/) , , , ... (Due to the length of these URLs, it may be necessary to copy ...
... AHMEDABAD, India , June 21, 2010 ... healthcare companies has,received Phase I clinical trial permission from the DCGI for ... Centre using a,unique platform technology, ZYOG1 is a novel, oral, anti-diabetic molecule. ... ...
Cached Medicine Technology:Cardiovascular Devices Market Outlook June Update by ReportsandReports 2Cardiovascular Devices Market Outlook June Update by ReportsandReports 3Cardiovascular Devices Market Outlook June Update by ReportsandReports 4Cardiovascular Devices Market Outlook June Update by ReportsandReports 5Cardiovascular Devices Market Outlook June Update by ReportsandReports 6Cardiovascular Devices Market Outlook June Update by ReportsandReports 7Cardiovascular Devices Market Outlook June Update by ReportsandReports 8Cardiovascular Devices Market Outlook June Update by ReportsandReports 9Cardiovascular Devices Market Outlook June Update by ReportsandReports 10Zydus' Novel Orally Administered GLP-1 Agonist - 'ZYOG1' to treat Diabetes and Obesity Enters Phase I Clinical Trial 2Zydus' Novel Orally Administered GLP-1 Agonist - 'ZYOG1' to treat Diabetes and Obesity Enters Phase I Clinical Trial 3
... (PTH) is synthesized by the parathyroid ... to decreased extracellular calcium concentrations. PTH ... and decreasing calcium excretion by the ... intact PTH is rapidly degraded into ...
ACTIVATED CLOTTING TIME SYSTEM...
... Erythropoietin (EPO) is the primary known ... The predicted molecular weight of human EPO ... circulating form of EPO has an estimated ... itself appears to have a unique structure, ...
... versatility. Positron Corporation is the exclusive distributor ... whole body PET scanners. This unique performance ... quality images in clinical oncology, cardiology, and ... only scanner on the market that is ...
Medicine Products: