Navigation Links
For children with sickle cell disease, lung disease is part of the package
Date:5/18/2008

ATS 2008, TORONTOChildren with sickle cell disease (SCD) have a significantly sharper decline in lung function with age when compared to other children of the same race and age. Furthermore, that loss of function appears to be linked to a restrictive rather than obstructive pattern, contrary to previous research that has focused on obstructive or asthma-like patterns in loss of lung function with sickle cell disease. The research will be presented at the American Thoracic Societys 2008 International Conference in Toronto on Sunday, May 18.

The restrictive pattern of decline is supportive of early injury or inflammation resulting in progressive changes in lung volumes across age, said lead researcher Joanna MacLean, M.D., of the department of respiratory medicine at Childrens Hospital at Westmead in Australia. We expected that children with sickle cell disease would show greater loss of lung function than other children, but this had never been quantified, nor was the pattern of decline clear.

To determine the patterns of loss of lung function, the researchers analyzed 1,357 lung function results that were completed between January 1989 and January 2005 on from 413 children with SCD during routine sickle cell clinical visits. Lung volume measurements were also included for 1,129 records.

They found that over time, there was a significant decline in lung function shown by a decline in the percent predicted values for all spirometry measures except FEV1/FVC ratio, a marker of airway obstruction. The pattern of decline of lung volume confirmed a restrictive pattern with an average loss of 2 percent per year of total lung capacity.

This is the first study to examine loss of lung function in children with sickle cell disease over time in a large number of children. Most studies of lung function in children with sickle cell disease are either cross-sectional or have limited longitudinal follow-up, said Dr. MacLean. The strength of our study is that
'/>"/>

Contact: Keely Savoie
ksavoie@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Children of depressed moms do better when dad is involved, SLU researcher finds
2. High pollution linked to poor lung function growth in children in Mexico City
3. NYC-area 1st: Morgan Stanley Childrens Hospital performs transcatheter pulmonary valve replacement
4. Obese Children Miss More School Days
5. Ultra-Runner to Run 63 Marathons in 63 Days for Children with Incurable Disease
6. Psoriasis Cure Now offers Back to School Resources for Parents of Children with Psoriasis
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Practice-based intervention has sustained benefits for children and families
10. 1.5 million children could be saved
11. Annual flu shot cuts need for doctors visits, hospitalization among children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... This morning(July 9th, 2014 at 8 am), ... discuss the illegal immigration crisis at our southern border and ... , Dr. Flinn told Good Morning Memphis host Ernie Freeman, ... The problem is that they do not have enough agents ... day are coming into the border; the border isn’t protected.” ...
(Date:7/11/2014)... 11, 2014 People with physical disabilities ... some of the increasing numbers of people partnered with ... independent and productive lives. , But are these ... an assistance dog an impediment to employment? , ... August 3 - 9, 2014, West Virginia University associate ...
(Date:7/11/2014)... July 11, 2014 The Williams Rejuva ... part of each patient’s unique treatment regime. Using ... skin’s health and trouble areas can be quickly created. ... to be established. , Vectra 3D is a cutting-edge ... Vectra 3D uses a quick ‘snapshot’ of the skin ...
(Date:7/11/2014)... Texas (PRWEB) July 11, 2014 Yisrayl Hawkins, ... Texas, writes a letter pleading to let the children from ... to be allowed to come. Yisrayl says President Barack Obama ... need from the United States, and he wants to help ... children coming from Guatemala, Honduras and El Salvador being treated ...
(Date:7/11/2014)... Even the hot Texas sun won’t keep kids from having ... The school had previously invested in a playground structure to ... recently asked for an innovative solution to help protect children ... chose a Rectangular Shade from APCPLAY as the perfect solution ... The shade measures 24’W x 34’H x 11’H to ...
Breaking Medicine News(10 mins):Health News:Senate Candidate, George Flinn on Fox13 NEWS About the Border Crisis 2Health News:Will Your Next Employee or Co-Worker Be a Dog? 2Health News:Will Your Next Employee or Co-Worker Be a Dog? 3Health News:Will Your Next Employee or Co-Worker Be a Dog? 4Health News:Williams Rejuva Center Includes Innovative Computer Imaging 2Health News:Yisrayl Hawkins Backs Barack Obama’s Pleas to Let the Children Come to the U.S. in New Letter 2Health News:Yisrayl Hawkins Backs Barack Obama’s Pleas to Let the Children Come to the U.S. in New Letter 3Health News:Cool Fun Under the Texas Sun: Godley Elementary School Purchases Shade Structure from APCPLAY© 2
... working to ... Oct. 15 More than half of the children in,Indianapolis ... University School of Dentistry mobile project had moderate or,severe dental ... by the,university and funded in part by a grant from ...
... mathematician who has applied mathematical modeling techniques to elucidate the ... methods to ascertain the players most deserving of major league ... awards. Bukiet, a popular NJIT math professor, dives annually ... game, but also for his love of teaching and math. ...
... DUBLIN, Ohio, Oct. 15 Foresight Corporation ... Debra Strickland has joined the,company,s Development division ... http://www.newscom.com/cgi-bin/prnh/20081015/CLW134 ), In this role, ... customers to,propose and design new technical solutions, ...
... 15 deCODE genetics,(Nasdaq: DCGN ) today ... review of,its long-term business strategy. Over the past ... chemistry, structural biology and,human genetics to develop product ... diagnostics. The goal of this strategic,review is to ...
... Thanks Donor Family for New Hand, LOUISVILLE, Ky., ... transplant recipient headed home,yesterday (Oct. 14) to Upland, California, ... new right hand during a 14-hour surgical,procedure performed by ... on July 12, 2008 at Jewish Hospital., "I ...
... Cenegenics Education and Research Foundation partnered with two recognized ... of Medicine to examine testosterone and/or human growth hormone ... body composition and quality of life. Favorable findings from ... Journal of Multidisciplinary Healthcare, part of Dove Open Access. ...
Cached Medicine News:Health News:SEAL Indiana Reports More Than Half of Indianapolis Area School Kids Treated by Program Have Moderate or Severe Dental Decay 2Health News:Using math model, NJIT professor names MVP and Cy Young award contenders 2Health News:Using math model, NJIT professor names MVP and Cy Young award contenders 3Health News:Debra Strickland joins Foresight Corporation in time for HIPAA 5010 Mandate 2Health News:deCODE Conducting Strategic Review to Sharpen the Focus of its Long-term Business 2Health News:deCODE Conducting Strategic Review to Sharpen the Focus of its Long-term Business 3Health News:deCODE Conducting Strategic Review to Sharpen the Focus of its Long-term Business 4Health News:Fourth Hand Transplant Recipient Heads Home to California 2Health News:Hormone Normalization Shows Encouraging Effects In Documented Clinically Deficient Men/Women 2Health News:Hormone Normalization Shows Encouraging Effects In Documented Clinically Deficient Men/Women 3
(Date:7/10/2014)... 11, 2014  Major advances in radiation therapy ... being highlighted in a three-day Oncology Summit taking ... July, 2014.  Renowned national and international cancer experts from ... and exchange knowledge on modern technologies making treatment ... The Summit will address a ...
(Date:7/10/2014)... NEWPORT NEWS, Virginia , 11. ... führender Hersteller von Kameras für die ... Brust (MBI/BSGI), hat heute die CE-Zulassung ... Mit dem CE-Zeichen kann Dilon das ... seinen Vertriebsbereich auf den Großteil der ...
(Date:7/10/2014)... U.S. Department of Health and Human Services (HHS) has ... Medical Center Seidman Cancer Center totaling $4.7 million to ... for patients with complex cancer. Titled ... model developed at UH to enhance care for adult ... need for high health care utilization.  ...
Breaking Medicine Technology:Improving quality and access to advanced cancer care in India and South Asia 2Improving quality and access to advanced cancer care in India and South Asia 3Improving quality and access to advanced cancer care in India and South Asia 4Improving quality and access to advanced cancer care in India and South Asia 5Dilon erhält CE-Zulassung für sein Navigator-Gamma-Sondensystem 2University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 2University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 3University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 4
... 2011 Vanda Pharmaceuticals Inc. (Nasdaq: VNDA ... granted orphan drug designation for tasimelteon, an oral dual ... Non-24-Hour Sleep/Wake Disorder (N24HSWD) in blind individuals with no ... designation that the Committee for Orphan Medicinal Products (COMP) ...
... China, March 8, 2011 /PRNewswire-Asia/ -- Simcere Pharmaceutical Group ... a leading pharmaceutical company specializing in the development, manufacturing, ... today reported unaudited financial results for the fourth quarter ... Highlights Total revenue was ...
Cached Medicine Technology:Vanda Pharmaceuticals Receives Orphan Drug Designation in Europe for tasimelteon 2Vanda Pharmaceuticals Receives Orphan Drug Designation in Europe for tasimelteon 3Vanda Pharmaceuticals Receives Orphan Drug Designation in Europe for tasimelteon 4Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2010 Results 2Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2010 Results 3Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2010 Results 4Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2010 Results 5Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2010 Results 6Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2010 Results 7Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2010 Results 8Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2010 Results 9Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2010 Results 10Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2010 Results 11Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2010 Results 12
... when it comes to superior immobilization and cervical ... job., ,You already know that the most ... of the c-spine. But what you may not ... Medical's NECLOC ®: provides superior immobilization over the ...
Distinct male and female designs for proper anatomical fit. Hip and pelvic components sized independently. Rigid posterior tongue minimizes pelvic rotation. Available in black or white plastic. Aggre...
... The B3 Triplanar hip joint ... Flexion - extension, abduction - ... on our Boston Post-Op Hip ... our custom Hip Spicas in ...
... Impact is the most significant advance in walker design ... unique design where the weight bearing surfaces of the ... impact is absorbed at the heel strike. The footbed ... the foot for added comfort and stability. , ...
Medicine Products: