Navigation Links
For Some, Virtual Colonoscopy May Be Just As Good
Date:6/16/2009

Less invasive test might spur more people to be screened, experts say,,,,

TUESDAY, June 16 (HealthDay News) - CT colonography, a less invasive option to colonoscopy, is an effective way to detect colon cancer in people who have an elevated risk of the disease because of family history or a personal history of colon polyps, new research has found.

However, the study, in the June 17 issue of the Journal of the American Medical Association, reports that CT colonography (also known as "virtual colonoscopy") is less effective at correctly identifying colon cancers in people who've had a positive fecal occult blood test (FOBT), which means they have blood in their stool. A positive FOBT is a strong indicator that cancer might be present.

"People should be aware that colorectal cancer is a preventable disease," said one of the study's authors, Dr. Cristiana Laudi, a senior clinical researcher in the departments of gastroenterology and radiology at the Institute for Cancer Research and Treatment in Candiolo, Turin, Italy. "Our data suggest that CT colonography may provide a valid screening test also in subjects at increased risk of colorectal cancer."

Laudi said the findings are particularly important because colonoscopy screenings tend to have low adherence rates, and a less invasive test might boost compliance rates.

The American Cancer Society already recommends CT colonography as an option for people who have an average risk of colorectal cancer, according to Dr. Durado Brooks, director of colorectal cancer for the society. And the study, he said, provides some evidence that CT colonography might also be useful in high-risk populations.

"The sensitivity for cancer was extremely high," Brooks said. But the test did miss some polyps, he added. And he cautioned that the findings need to be confirmed by others before any definitive recommendations can be made.

The study included 937 people who were considered at high risk for colorectal cancer because of a family history of the disease (373 people), a personal history of colon polyps (343 people) or a positive result on the FOBT (221 people). The participants were recruited from 11 medical centers in Italy and one in Belgium. They averaged 60 years old.

Each participant underwent CT colonography followed by colonoscopy on the same day. Preparation for CT colonography is usually the same as is used for colonoscopy, though Laudi said that a less potent laxative is sometimes used. But, the colon still needs to be emptied and clean for the CT test. Colonoscopy can be used to screen, diagnose and treat colorectal cancers, but it is considerably more invasive, carries a greater risk of complications and often requires sedation.

Overall, the virtual test found 85 percent of the colorectal cancers detected by colonoscopy. False-positive rates were 4 percent for advanced cancers and 15 percent for people with a positive FOBT.

"Virtual colonoscopy is a valid screening test for colorectal cancer, trading off a better acceptance and lesser invasiveness by comparison with colonoscopy, with the possibility of missing small polyps that may, however, not be so relevant in terms of risk of developing into cancer," Laudi said.

Because a positive FOBT indicates a strong likelihood of cancer and a need for treatment, Brooks said he wouldn't recommend CT colonography for people with a positive test unless there were some extraordinary individual circumstances that prevented the use of colonoscopy.

"The question remains whether clinicians are willing to accept a study with decreased sensitivity for the potential of increased adherence with recommended screening and surveillance guidelines," wrote Dr. Emily Finlayson from the University of Michigan, in an accompanying editorial in the same issue of the journal. "With the majority of individuals in the United States who meet the criteria for colorectal cancer screening and surveillance not undergoing recommended procedures, an imperfect test that has a lower risk profile and greater acceptance among patients seems to be an appealing solution."

However, people on Medicare or Medicaid currently do not have the option of CT colonography unless they're willing to pay out of pocket for the test. In May, the U.S. Centers for Medicare and Medicaid Services said that there was insufficient evidence to support the use of the test.

More information

The Radiological Society of North America has more on CT colonography.



SOURCES: Cristiana Laudi, M.D., senior clinical researcher, gastroenterology and radiology, Institute for Cancer Research and Treatment, Candiolo, Turin, Italy; Durado Brooks, M.D., director, colorectal cancer, American Cancer Society; June 17, 2009, Journal of the American Medical Association


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. For Some, Virtual Colonography May Be Just As Good
2. NIH May Ease Some, But Not All, Stem Cell Restrictions
3. For Some, More Costly Care Is Not by Choice
4. For Some, Diabetes Care Worse Than Illness Itself
5. VirtualHealth and Silk Partner to Provide Physicians with Revenue Recovery Solutions
6. Fujifilm Takes Virtualization Technology to Next Level
7. VirtualScopics Regains NASDAQ Compliance
8. Cabot Creamery Cooperatives Vermont to Vegas Online Health and Fitness Challenge is a Virtual Blast
9. Study finds virtual doctors visits satisfactory for both patients and clinicians
10. Medicares No on Virtual Colonoscopy Stirs Expert Debate
11. Decision by Medicares CMS to Deny Coverage for Virtual Colon Cancer Tests Underscores Lack of Evidence on Cancer Prevention
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
For Some, Virtual Colonoscopy May Be Just As Good
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, ... Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments in ... the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in ...
(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort ... holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain ... Disease (SCD) is a disorder of the red blood cells, which can cause episodes ...
(Date:6/24/2016)... ... 24, 2016 , ... Dr. Amanda Cheng, an orthodontist ... has extensive experience with all areas of orthodontics, including robotic Suresmile technology, ... , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can be used ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB Medicine ... Making in Emergency Medicine conference in Ponte Vedra Beach, FL. The awards honor ... Emergency Medicine Practice and Pediatric Emergency Medicine Practice. , “With this ...
(Date:6/24/2016)... ... 24, 2016 , ... National recruitment firm Slone Partners is pleased ... and genomics experience, as Vice President of North American Capital Sales at HTG ... leading the sales team in the commercialization of the HTG EdgeSeq system and associated ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016  Global Blood ... biopharmaceutical company developing novel therapeutics for the treatment ... today announced the closing of its previously announced ... stock, at the public offering price of $18.75 ... offering were offered by GBT. GBT estimates net ...
(Date:6/24/2016)... June 24, 2016 ... announced the addition of the " Global Markets ... This report focuses ... an updated review, including its applications in various applications. ... market, which includes three main industries: pharmaceutical and biotechnology, ...
(Date:6/24/2016)... , June 24, 2016 The Academy ... of recommendations that would allow biopharmaceutical companies ... with entities that make formulary and coverage decisions, a ... "value" of new medicines. The recommendations address ... not appear on the drug label, a prohibition that ...
Breaking Medicine Technology: