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For Reducing Mortality, Current and Emerging Therapies Have No Advantage Over Carvedilol in the Treatment of Coronary Heart Disease (Stable Angina)
Date:4/20/2009

Percutaneous Coronary Intervention Will Retain Decision Resources' Clinical Gold Standard for Stable Angina, According to a New Report from Decision Resources

WALTHAM, Mass., April 20 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that surveyed cardiologists identify a therapy's effect on mortality as the attribute that most influences their prescribing decisions in coronary heart disease (stable angina). Clinical data and the opinions of interviewed thought leaders indicate that current and emerging therapies have no advantage in this attribute over carvedilol (GlaxoSmithKline's Coreg, generics), the sales-leading agent in the market.

The new report entitled Coronary Heart Disease (Stable Angina): To Gain Share, Emerging Therapies Must Not Only Control Symptoms but Also Reduce Mortality also finds that a therapy that reduces plaque volume more than Pfizer's Lipitor/Sortis/Tahor at 18 months would earn a 28 percent patient share in stable angina in the United States and a 37 percent patient share in Europe, according to surveyed U.S. and European cardiologists.

In 2008, Decision Resources' proprietary clinical gold standard for stable angina was percutaneous coronary intervention (PCI). Based on available data and expert opinion, PCI will retain gold-standard status for stable angina in 2012 as surveyed physicians believe it to be the most efficacious therapy for treating the symptoms of stable angina.

"Interestingly, surveyed physicians also indicate that Cardium Therapeutics' gene therapy Generx has great potential in treating stable angina," said Decision Resources Analyst Kate Sullivan, B.S. "However, experts we interviewed believe gene therapy is still at least 10 years away from becoming a viable therapeutic approach for the indication, which leaves PCI, over the next decade, as the most e
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SOURCE Decision Resources
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