Navigation Links
For Older Men, Lowered Testosterone May Mean Muscle Loss
Date:10/28/2011

FRIDAY, Oct. 28 (HealthDay News) -- Lowered testosterone levels are associated with the loss of lean muscle mass and lower body strength in older men, a new study finds.

Loss of muscle mass and strength contributes to frailty and is associated with mobility problems, falls and bone fractures, the study's authors say, and men lose more muscle mass and strength than women as they age.

That suggests that levels of sex hormones, particularly testosterone, could influence age-related changes in body composition and physical function, according to researchers led by Dr. Erin LeBlanc, of Kaiser Permanente Northwest in Portland, Ore.

Their study included almost 1,200 men aged 65 who had their levels of sex steroids measured and were then followed for an average of 4.5 years. Their body composition was checked using high-tech scans, and their physical abilities were evaluated through exercises that assessed lower extremity power, grip strength, walking speed and the ability to rise from a chair without the use of arms.

"Our study finds that men, aged 65 years and older, with higher testosterone levels lost less muscle mass, especially in their arms and legs, than men this age who had lower testosterone levels," LeBlanc said in an Endocrine Society news release.

"Men who had higher testosterone levels before they lost weight also lost less leg function and could stand up more easily from a chair than men who had lower testosterone levels before they lost weight," she noted.

"The amount of testosterone men have in their bodies may contribute to how much muscle and strength they lose as they get older," LeBlanc concluded.

One expert wasn't surprised by the findings, but added that they are no reason to urge older men towards supplemental testosterone.

The study "confirms that higher blood levels of testosterone in older men is associated with less of the loss of muscle mass that occurs with aging," said Dr. Stuart Weinerman, chief of the division of endocrinology at North Shore-LIJ Health System in New Hyde Park, N.Y. But he stressed that "this is a prospective epidemiological study, not a controlled trial, so that other variables may be present. For example, patients with low testosterone were more likely to have diabetes."

Weinerman added that "this study should not be interpreted as evidence that hypogonadal men [those with decreased testosterone output] should begin testosterone replacement. The risks and benefits of testosterone replacement can only be studied in larger, randomized controlled trials."

Another expert said testosterone levels may need watching as men age.

"Physicians should be checking testosterone levels in men older than age 65, discussing loss of muscle mass and potential of falls and resulting fractures," said Dr. Spyros Mezitis, an endocrinologist at Lenox Hill Hospital in New York City. "Further research is needed to define the association of low testosterone levels and decrease in physical function," he added.

The study, funded by grants from the U.S. National Institutes of Health, is slated to be published in the Journal of Clinical Endocrinology & Metabolism.

More information

The U.S. National Institute on Aging offers tips for health aging.

-- Robert Preidt

SOURCE: Stuart Weinerman, M.D., chief, division of endocrinology, North Shore-LIJ Health System, New Hyde Park, N.Y.; Spyros Mezitis, M.D., endocrinologist, Lenox Hill Hospital, New York City; Endocrine Society, news release, Oct. 27, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Watch your step: Elevator-related injuries and older adults
2. California IVF Discount/Rebate Program Eases Risk for Older Mothers
3. Diabetes drug ups risk for bone fractures in older women
4. Autism Science Foundation Offers IMFAR Grants to Autism Stakeholders
5. Americans Recognize Risk of Fire to Older Adults
6. Key Pillars of Patient Centered Medical Home Will Be Focus of March 30 Patient-Centered Primary Care Collaborative Stakeholders Meeting
7. Kidneys From Older Donors Suitable for Seniors
8. Screens, Vaccine for HPV Less Beneficial in Older Women
9. Tyco International to Host 2010 Annual General Meeting of Shareholders
10. Midlife crisis: Unmarried older women twice as likely to lack health insurance, study shows
11. New clues found linking larger animals to colder climates
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
For Older Men, Lowered Testosterone May Mean Muscle Loss
(Date:10/13/2017)... ... October 13, 2017 , ... The American Board of Family ... next President and Chief Executive Officer, succeeding Dr. James C. Puffer upon his retirement. ... 1, 2018 until Dr. Puffer’s retirement at the end of 2018. Upon assuming the ...
(Date:10/13/2017)... ... ... Lori R. Somekh, founder of the Law Office of Somekh & ... and special needs planning attorneys. “Membership in ElderCounsel helps our office remain up to ... with elder law attorneys nationwide,” said Somekh. , ElderCounsel was founded ...
(Date:10/13/2017)... NY (PRWEB) , ... October 13, 2017 , ... Ellevate ... people in business to advocate for action towards gender equality at their inaugural Summit ... from around the globe, and reached a social audience of over 3 million. To ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader ... been awarded a contract by the Center for Medicare and Medicaid Services (CMS). ... the enterprise use of Agile methodologies in a consistent and high value manner ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... now treating sleep apnea using cutting-edge Oventus O2Vent technology. As many ... sleep disorder characterized by frequent cessation in breathing. Oral appliances can offer significant ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... PROVIDENCE, R.I. , Sept. 25, 2017 /PRNewswire/ ... immunogenicity assessment, vaccine design, and immune-engineering today announced ... focused on the development of personalized therapeutic cancer ... and has provided exclusive access to enabling technologies ... MSc Eng., MBA will lead EpiVax Oncology as ...
(Date:9/22/2017)... , Sept. 22, 2017  As the latest ... Senators Bill Cassidy (R-LA) and Lindsey ... notes that the medical device industry is in an ... device tax, the 2.3% excise tax on medical device ... they also want covered patients, increased visits and hospital ...
(Date:9/19/2017)... , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device company developing a ... targeted tissues, announced three leadership team developments today:   ... ... ... Veteran medical device executive Josh Stopek , ...
Breaking Medicine Technology: