Navigation Links
Food elimination diet identifies causes of difficulty swallowing and swelling of the throat
Date:6/20/2012

A six-food elimination diet significantly improves symptoms in adult patients with eosinophilic esophagitis (EoE), according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. In EoE, eosinophils and other inflammatory cells cause inflammation of the esophagus in response to an allergic stimulus. Previously thought to be a rare disease, EoE has become one of the most common causes for dysphagia (difficulty swallowing), heartburn and the sensation of "food stuck in the throat" in adults. Similar to children, this study has now shown that food allergens have a causative role in the majority of adults with EoE.

An elimination diet that identifies specific food triggers is an effective therapeutic alternative to corticosteroids for adults with EoE. Furthermore, the results of a reintroduction process in which these trigger foods are added back into a patient's diet support the fact that food antigens are driving this response; this provides new insight into the nature of the inflammatory response in adult EoE.

"By first eliminating, then systematically reintroducing foods in our adult patients, we were able to identify the specific food triggers that caused their symptoms, such as heartburn, chest pain and difficulty swallowing, or the sensation of food being stuck in their throat," said Nirmala Gonsalves, MD, of Northwestern University and the lead author of this study. "Given the poor sensitivity of skin prick testing and lack of history of food allergy or intolerance, the six-food elimination diet with reintroduction is the only reliable method to date to identify food triggers in adult eosinophilic esophagitis and should allow us to better tailor diet to individual patients for long-term management." View a video abstract in which Dr. Gonsalves discusses her study findings.

A diet that eliminates all of the six most commonly allergenic foods (milk, soy, egg, wheat, peanuts/tree nuts and shellfish/fish) significantly improves symptoms and reduces esophageal tissue damage associated with EoE in adults. In fact, 78 percent of patients achieved greater than a 50 percent reduction in peak eosinophil (white blood cell) counts in their esophagus; dysphagia symptom scores improved significantly after the elimination diet. Once trigger foods were reintroduced, all patients had recurrence of their symptoms within five days. These results suggest that EoE is likely the same disease in children and adults.


'/>"/>
Contact: Alissa J. Cruz
media@gastro.org
301-272-1603
American Gastroenterological Association
Source:Eurekalert

Related medicine news :

1. New study identifies promising, achievable solutions to Nigerias childhood mortality crisis
2. Study identifies potential treatment for lethal childhood leukemia
3. New study identifies how information technology is used to solve global health challenges
4. Study identifies possible protective blood factors against Type 2 diabetes
5. Genetic test identifies eye cancer tumors likely to spread
6. 3-center study identifies main causes of unprofessional behavior among hospitalists
7. Global Energy Assessment identifies pathways to a sustainable energy future
8. Study reveals how cancer drug causes diabetic-like state
9. What Causes Hot Flashes, Anyway?
10. No Proof That Gum Disease Causes Heart Disease, Experts Say
11. A new Achilles heel in fungus that causes dandruff
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/9/2016)... ... February 09, 2016 , ... METTLER TOLEDO has published a ... a basic understanding of the techniques they use so they can more easily ... reduce waste and rework to create a leaner overall lab experience. , ...
(Date:2/9/2016)... ... February 09, 2016 , ... United Methodist Communications collaborated ... Prevention,” an animated video designed to prevent the next widespread Ebola ... video are being distributed throughout Togo, Liberia, Sierra Leone, Nigeria, Côte d’Ivoire and ...
(Date:2/9/2016)... ... ... and Kevin Harrington, and the Product Managers of AsSeenOnTV.pro are pleased to announce the ... that has solved some of the basic problems golfers have faced since the dawn of ... a rain shower, might understand the struggle of placing the club down for a split ...
(Date:2/8/2016)... (PRWEB) , ... February 08, 2016 , ... ... launched its newly redesigned website, federallabs.org . The site houses a wealth ... license available federal technologies through the process called technology transfer (T2). As a ...
(Date:2/8/2016)... ... 08, 2016 , ... Stephanie Hebert Insurance Agency, serving families ... new charity campaign. As part of their ongoing community involvement program, funds are ... that children deserve a voice, and in the spirit of neighbors helping neighbors ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... , Feb.8, 2016 Cardiac ... Summary GlobalData,s Medical Devices sector report, ... Assessment, 2015 " provides an overview of Cardiac ... report provides comprehensive information on the pipeline products ... stages of development. The report reviews major players ...
(Date:2/8/2016)... Respiratory Devices - Medical Devices Pipeline ... sector report, " Respiratory Devices - Medical Devices ... Respiratory Devices currently in pipeline stage. The ... with comparative analysis of the products at various ... involved in the pipeline product development. It also ...
(Date:2/8/2016)... 2016 Aesthetic Devices - Medical Devices Pipeline ... report, "Aesthetic Devices - Medical Devices Pipeline Assessment, 2015" ... stage. This report is prepared using ... by GlobalData,s team of industry experts. *Note: Certain ... based on the availability and relevance of data in ...
Breaking Medicine Technology: