Navigation Links
Food elimination diet identifies causes of difficulty swallowing and swelling of the throat

A six-food elimination diet significantly improves symptoms in adult patients with eosinophilic esophagitis (EoE), according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. In EoE, eosinophils and other inflammatory cells cause inflammation of the esophagus in response to an allergic stimulus. Previously thought to be a rare disease, EoE has become one of the most common causes for dysphagia (difficulty swallowing), heartburn and the sensation of "food stuck in the throat" in adults. Similar to children, this study has now shown that food allergens have a causative role in the majority of adults with EoE.

An elimination diet that identifies specific food triggers is an effective therapeutic alternative to corticosteroids for adults with EoE. Furthermore, the results of a reintroduction process in which these trigger foods are added back into a patient's diet support the fact that food antigens are driving this response; this provides new insight into the nature of the inflammatory response in adult EoE.

"By first eliminating, then systematically reintroducing foods in our adult patients, we were able to identify the specific food triggers that caused their symptoms, such as heartburn, chest pain and difficulty swallowing, or the sensation of food being stuck in their throat," said Nirmala Gonsalves, MD, of Northwestern University and the lead author of this study. "Given the poor sensitivity of skin prick testing and lack of history of food allergy or intolerance, the six-food elimination diet with reintroduction is the only reliable method to date to identify food triggers in adult eosinophilic esophagitis and should allow us to better tailor diet to individual patients for long-term management." View a video abstract in which Dr. Gonsalves discusses her study findings.

A diet that eliminates all of the six most commonly allergenic foods (milk, soy, egg, wheat, peanuts/tree nuts and shellfish/fish) significantly improves symptoms and reduces esophageal tissue damage associated with EoE in adults. In fact, 78 percent of patients achieved greater than a 50 percent reduction in peak eosinophil (white blood cell) counts in their esophagus; dysphagia symptom scores improved significantly after the elimination diet. Once trigger foods were reintroduced, all patients had recurrence of their symptoms within five days. These results suggest that EoE is likely the same disease in children and adults.

Contact: Alissa J. Cruz
American Gastroenterological Association

Related medicine news :

1. New study identifies promising, achievable solutions to Nigerias childhood mortality crisis
2. Study identifies potential treatment for lethal childhood leukemia
3. New study identifies how information technology is used to solve global health challenges
4. Study identifies possible protective blood factors against Type 2 diabetes
5. Genetic test identifies eye cancer tumors likely to spread
6. 3-center study identifies main causes of unprofessional behavior among hospitalists
7. Global Energy Assessment identifies pathways to a sustainable energy future
8. Study reveals how cancer drug causes diabetic-like state
9. What Causes Hot Flashes, Anyway?
10. No Proof That Gum Disease Causes Heart Disease, Experts Say
11. A new Achilles heel in fungus that causes dandruff
Post Your Comments:
(Date:6/27/2016)... ... June 27, 2016 , ... TherapySites, ... its affiliation with Tennessee Counseling Association. This new relationship allows TherapySites ... Tennessee Counseling Association, adding exclusive benefits and promotional offers. , "TCA is extremely ...
(Date:6/27/2016)... ... ... recently awarded their highest five-star rating to Best Buy Eyeglasses, an ... United States and Canada wear eyeglasses. Once considered to be a purely functional part ... fashion statement. Even celebrities use glasses as a way of creating an iconic image—like ...
(Date:6/26/2016)... ... 2016 , ... Pixel Film Studios Released ProSlice Levels, a Media Slicing Effect ... videos a whole new perspective by using the title layers in ProSlice Levels ... , ProSlice Levels contains over 30 Different presets to choose from. FCPX ...
(Date:6/26/2016)... Lake Orion, Clarkston, Michigan (PRWEB) , ... June ... ... direction with respect to fertility once they have been diagnosed with endometriosis. These ... tolerable intercourse but they also require a comprehensive approach that can help for ...
(Date:6/25/2016)... ... ... closing of Bruton Memorial Library on June 21 due to a possible lice infestation, as ... of head lice: the parasite’s ability to live away from a human host, and to ... one in the event that lice have simply gotten out of control. , As lice ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 Research ... World Market for Companion Diagnostic Tests" report to their ... Market for Companion Diagnostics The World Market ... and personalized medicine diagnostics. Market analysis in the report includes ... Test Market (In Vitro Diagnostic Kits) by Region (N. America, ...
(Date:6/24/2016)... Mass. , June 24, 2016   Pulmatrix, ... pharmaceutical company developing innovative inhaled drugs, announced today that ... Russell Investments reconstituted its comprehensive set of ... "This is an important milestone for Pulmatrix," ... will increase shareholder awareness of our progress in developing ...
(Date:6/24/2016)... June 24, 2016  Arkis BioSciences, a leading ... and more durable cerebrospinal fluid treatments, today announced ... Series-A funding is led by Innova Memphis, followed ... other private investors.  Arkis, new financing will accelerate ... the market release of its in-licensed Endexo® technology. ...
Breaking Medicine Technology: