Navigation Links
Food dye could provide 'blueprint' for treatment of Panx1-related diseases
Date:4/29/2013

The food dye Brilliant Blue FCF (BB FCF) could be a useful tool in the development of treatments for a variety of conditions involving the membrane channel protein Pannexin 1(Panx1), according to a study in The Journal of General Physiology. Panx1, which is involved in signaling events leading to inflammation and cell death, has been implicated in such diverse diseases as Crohn's, AIDS, melanoma, epilepsy, spinal cord injury, and stroke, among others. Thus, there is a demand for the development of pharmacological tools to inhibit Panx1.

Researchers from the University of Miami School of Medicine now demonstrate that BB FCF is a selective inhibitor of Panx1 and might therefore be added to the repertoire of drugs used to battle certain diseases associated with the protein. However, because an unintended consequence of treatment with BB FCF could be a temporary blue skin tone in patients, the researchers conclude that BB FCF would be best used to identify structurally similar substances to aid treatment.


'/>"/>

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press
Source:Eurekalert

Page: 1

Related medicine news :

1. Could Facebook Assist Public Health Efforts to Track Obesity?
2. Roadside Breath Test for Drugs Could Be on Horizon
3. Cardio could hold key to cancer cure
4. Gene Studies Could Point to New Alzheimers Treatments
5. U.S. Heart Failure Costs Could Skyrocket: Report
6. Shoulder injuries in baseball pitchers could be prevented with 3-D motion detection system
7. Gene variant ID could lead to better fatty liver disease diagnosis
8. Could Turtle Gene Findings Aid Human Health?
9. Smoking Bans in Public Housing Could Save Dollars, Lives: CDC
10. Drug could improve working memory of people with autism, study finds
11. La Jolla Institutes surprising finding could alter the face of dengue vaccine development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/8/2016)... ... December 08, 2016 , ... The West Virginia Medical ... 2017. The name change aligns the entire company with its existing Quality ... quality. , “We are very proud of the achievements associated with the West ...
(Date:12/8/2016)... ... December 08, 2016 , ... ZyDoc ... Language Processing–Enabled and Conventional Data Capture Methods for Input to Electronic Health Records: ... , Results of the comparative usability study demonstrate that a dictation-based method (“NLP ...
(Date:12/8/2016)... (PRWEB) , ... December 08, 2016 , ... With the ... created the “What’s In Your Mouth?” (WIYM) campaign to inform dentists and patients about ... Dentistry, the dental implant and prosthetic market in the U.S. is projected to reach ...
(Date:12/8/2016)... (PRWEB) , ... December 08, ... ... Presence Suite 10.2 version gives development continuity to its innovative Unified Instance ... channels management capacity. In addition, this new version optimizes the unattended auto-dialing ...
(Date:12/8/2016)... ... ... California Senate Bill (SB) 863, signed into law in 2012, may have ... according to CompScope™ Medical Benchmarks for California, 17th Edition , a study by ... payments per claim in California decreased 4 percent in 2013 and then 3 percent ...
Breaking Medicine News(10 mins):
(Date:12/9/2016)... Pa. , Dec. 9, 2016 Department ... announced temporary regulations for medical marijuana dispensaries under Act ... Pennsylvania Bulletin , and are now available online ... is needed in the plan for operation; process for ... dispensary; as well as where the dispensary facilities can ...
(Date:12/8/2016)... Australia Ophthalmic Lasers Market Outlook to 2022 ... Market Outlook to 2022", provides key market data on ... in millions of US dollars, volume (in units) and ... Femtosecond Lasers and YAG Lasers. The report also ... of these market segements, and global corporate-level profiles of ...
(Date:12/8/2016)... Global Interventional Radiology Market: Scope and ... radiology market analyzes the current and future prospects ... executive summary, including a market snapshot that provides ... The research is a combination of primary and ... our research efforts along with information collected from ...
Breaking Medicine Technology: