Navigation Links
Food dye could provide 'blueprint' for treatment of Panx1-related diseases
Date:4/29/2013

The food dye Brilliant Blue FCF (BB FCF) could be a useful tool in the development of treatments for a variety of conditions involving the membrane channel protein Pannexin 1(Panx1), according to a study in The Journal of General Physiology. Panx1, which is involved in signaling events leading to inflammation and cell death, has been implicated in such diverse diseases as Crohn's, AIDS, melanoma, epilepsy, spinal cord injury, and stroke, among others. Thus, there is a demand for the development of pharmacological tools to inhibit Panx1.

Researchers from the University of Miami School of Medicine now demonstrate that BB FCF is a selective inhibitor of Panx1 and might therefore be added to the repertoire of drugs used to battle certain diseases associated with the protein. However, because an unintended consequence of treatment with BB FCF could be a temporary blue skin tone in patients, the researchers conclude that BB FCF would be best used to identify structurally similar substances to aid treatment.


'/>"/>

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press
Source:Eurekalert

Page: 1

Related medicine news :

1. Could Facebook Assist Public Health Efforts to Track Obesity?
2. Roadside Breath Test for Drugs Could Be on Horizon
3. Cardio could hold key to cancer cure
4. Gene Studies Could Point to New Alzheimers Treatments
5. U.S. Heart Failure Costs Could Skyrocket: Report
6. Shoulder injuries in baseball pitchers could be prevented with 3-D motion detection system
7. Gene variant ID could lead to better fatty liver disease diagnosis
8. Could Turtle Gene Findings Aid Human Health?
9. Smoking Bans in Public Housing Could Save Dollars, Lives: CDC
10. Drug could improve working memory of people with autism, study finds
11. La Jolla Institutes surprising finding could alter the face of dengue vaccine development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2017)... ... 2017 , ... Horizon Goodwill Industries, SourceAmerica and ... high school girls succeed in STEM programs as well as help Horizon Goodwill ... over 20 high school girls at their corporate headquarters on Tuesday, July 25, ...
(Date:7/24/2017)... ... 2017 , ... The International Essential Tremor Foundation (IETF) will host a free ... The seminar will take place on Saturday, Aug. 26 at the Embassy Suites by ... run from 9 a.m. to 12 p.m., with check-in beginning at 8 a.m. The ...
(Date:7/24/2017)... NY (PRWEB) , ... July 24, 2017 , ... ... series of media initiatives designed to promote awareness for Topricin’s revolutionary, natural, after-burn ... elements is one of the leading causes of long term skin conditions, including ...
(Date:7/24/2017)... ... July 24, 2017 , ... Puregraft, the ... announces the issuance of United States Patent Number 9,695,398 (the '398 patent) and ... The '398 and '324 patents cover methods and systems for optimizing fat ...
(Date:7/24/2017)... ... July 24, 2017 , ... Sharon Kleyne, host of the nationally ... on VoiceAmerica sponsored by Nature’s Tears® EyeMist® recently talked on the air about an ... China. , The article by Zidor Aldama described the situation in which Chinese children ...
Breaking Medicine News(10 mins):
(Date:7/10/2017)... , July 10, 2017  The tenth annual ... Boston, MA at the Sheraton Boston Hotel, ... unparalleled access to global decision makers and innovative biotech ... life science leaders during two impactful days. BioPharm America ... delegates with additional networking opportunities with 4,500+ life science ...
(Date:7/5/2017)... JERUSALEM , July 5, 2017 ... www.oramed.com ), a clinical-stage pharmaceutical company ... today that it has received approval from the Israel Securities ... Stock Exchange (TASE). Oramed common stock will commence trading on ... Based on the current market capitalization of the Company, it ...
(Date:6/30/2017)... , June 30, 2017 In vitro ... the start of May, at least ten diagnostic companies ... private investments, public offerings and a loan facility.  The ... to almost $80 million.  Kalorama Information provides a monthly ... its Diagnostics Knowledge Center. ...
Breaking Medicine Technology: