Navigation Links
Food dye could provide 'blueprint' for treatment of Panx1-related diseases
Date:4/29/2013

The food dye Brilliant Blue FCF (BB FCF) could be a useful tool in the development of treatments for a variety of conditions involving the membrane channel protein Pannexin 1(Panx1), according to a study in The Journal of General Physiology. Panx1, which is involved in signaling events leading to inflammation and cell death, has been implicated in such diverse diseases as Crohn's, AIDS, melanoma, epilepsy, spinal cord injury, and stroke, among others. Thus, there is a demand for the development of pharmacological tools to inhibit Panx1.

Researchers from the University of Miami School of Medicine now demonstrate that BB FCF is a selective inhibitor of Panx1 and might therefore be added to the repertoire of drugs used to battle certain diseases associated with the protein. However, because an unintended consequence of treatment with BB FCF could be a temporary blue skin tone in patients, the researchers conclude that BB FCF would be best used to identify structurally similar substances to aid treatment.


'/>"/>

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press
Source:Eurekalert

Page: 1

Related medicine news :

1. Could Facebook Assist Public Health Efforts to Track Obesity?
2. Roadside Breath Test for Drugs Could Be on Horizon
3. Cardio could hold key to cancer cure
4. Gene Studies Could Point to New Alzheimers Treatments
5. U.S. Heart Failure Costs Could Skyrocket: Report
6. Shoulder injuries in baseball pitchers could be prevented with 3-D motion detection system
7. Gene variant ID could lead to better fatty liver disease diagnosis
8. Could Turtle Gene Findings Aid Human Health?
9. Smoking Bans in Public Housing Could Save Dollars, Lives: CDC
10. Drug could improve working memory of people with autism, study finds
11. La Jolla Institutes surprising finding could alter the face of dengue vaccine development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... EB Medicine ... Making in Emergency Medicine conference in Ponte Vedra Beach, FL. The awards honor ... Emergency Medicine Practice and Pediatric Emergency Medicine Practice. , “With this ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic Capital Partners, LLC ... by obtaining investment capital for emerging technology companies. SCP has delivered investment ... resulted in more than a million dollars of capital investment for five companies. ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... induced pluripotent stem (iPS) cells and other difficult to transfect cells, announces its ... The PluriQ™ G9™ Gene Editing System is a complete system for ...
(Date:6/24/2016)... ... June 24, 2016 , ... To ... infrastructure. Most providers, however, are unsure how to move forward, given the need ... define a path forward tailored to an organization’s specific needs. , PYA Principal ...
(Date:6/24/2016)... ... June 24, 2016 , ... SpiritQuest Sedona Retreats, located ... West Sedona, surrounded by famous vortex sites: Cathedral Rock, Airport Mesa, and Boynton Canyon. ... – the Lodge at Sedona as well as the Sedona Rouge, both popular accommodations ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 , ... Thursday, July 7, 2016 , , , , LOCATION: , ... , , , , EXPERT PANELISTS:  , , , Frost ... Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and Unmesh ... The global pharmaceutical industry is witnessing an exceptional era. Several ...
(Date:6/23/2016)... today announced the establishment of Astellas Farma Colombia (AFC), a new affiliate with operations headquartered in Bogota. ... ... ... ... Astellas is a ...
(Date:6/23/2016)... , June 23, 2016  Guerbet announced today that ... Supplier Horizon Award . One of ... was recognized for its support of Premier members through ... clinical excellence, and commitment to lower costs. ... this recognition of our outstanding customer service from Premier," ...
Breaking Medicine Technology: