Navigation Links
Food allergies more widespread among inner-city children
Date:8/14/2014

Already known for their higher-than-usual risk of asthma and environmental allergies, young inner-city children appear to suffer disproportionately from food allergies as well, according to results of a study led by scientists at the Johns Hopkins Children's Center.

The federally funded multi-center study, described online Aug. 13 in the Journal of Allergy and Clinical Immunology, found that at least one in 10 children from four large U.S. cities has a food allergy. However, the true number may be even higher, the investigators say, because the study used highly stringent criteria and counted only the three most common food allergies.

"Our findings are a wake-up call, signaling an urgent need to unravel the causes, contributors and mechanisms that drive the high prevalence of food allergies among an already vulnerable group known for its high risk of asthma and environmental allergies," says senior investigator Robert Wood, M.D., director of pediatric allergy and immunology at Johns Hopkins.

Nearly 3 percent of adults and 6 percent of young children in the United States have one or more food allergies, according to the latest estimates from the National Institutes of Health. Moreover, Wood notes, food allergies among children have been on a steady rise over the last 20 years, and experts have long suspected that children in urban areas are no exception. The new study largely affirms that trend but also points to a subgroup of children who may have higher-than-average allergy risk.

For the study, the investigative team followed 516 inner-city children from birth through age 5, living in Baltimore, Boston, New York City and St. Louis. Each year of the study, the investigators measured each child's exposure to household allergens, conducted physical exams, tracked the children's diets and reviewed their health histories. The team also analyzed blood samples at 1, 2, 3 and 5 years to measure the presence of food-specific immunoglobulin E (IgE) antibodies to milk, eggs and peanuts. IgE antibodies to food proteins are immune chemicals released by the body that herald a food allergy. Based on blood test results, other clinical findings and symptoms, the investigators classified a child as allergic, possibly allergic, sensitive to a particular substance or not sensitive. Sensitization to a substance, signaled by the presence of IgE antibodies in the blood, renders a person more likely to develop allergic symptoms, but it is not sufficient to diagnose a true food allergy, which is always marked by clinical symptoms. In this study, the investigative team deemed allergic only those children who had both clinical symptoms and elevated IgE antibodies. This stringent criterion likely underestimates the true number of kids with food allergies, Wood adds.

Overall, more than half (55 percent) of children in the study were classified as sensitive to milk, eggs or peanuts. Nearly 10 percent of them met criteria for a full-blown food allergy. The most common allergy was to peanuts (6 percent), followed by eggs (4.3 percent) and milk (2.7 percent). An additional 17 percent were classified as "possibly allergic," a subgroup that had elevated IgE antibodies but no clear history of allergic reactions to peanuts, eggs or milk. Twenty-nine percent were classified as "sensitive but tolerant," a group that included those with elevated IgE antibodies and a known history of consuming allergenic foods but who were able to tolerate the foods in question without allergic symptoms.

Breastfed children appeared to have a higher risk for developing food allergies. Children living in houses with higher levels of endotoxin, a molecule released by certain types of bacteria, were less likely to have a food allergy. This latter finding, the investigators say, is consistent with the so-called hygiene hypothesis, which suggests that early-life exposure to certain microbes can play a protective role against asthma and allergies.

Children with food allergies were also more likely to suffer from environmental allergies, wheezing and eczema, an allergic skin condition.


'/>"/>

Contact: Ekaterina Pesheva
epeshev1@jhmi.edu
410-502-9433
Johns Hopkins Medicine
Source:Eurekalert

Related medicine news :

1. Does Your Child Have Seasonal Allergies or a Cold?
2. City kids more likely to have food allergies than rural ones
3. NYC Doc Announces 3 Surprising Ways to Beat Seasonal Allergies
4. Study identifies causes for high rates of allergic reactions in children with food allergies
5. Rate of severe reactions higher than thought in young children with food allergies
6. More Vigilance Needed to Protect Kids With Food Allergies
7. Columbus Allergist Dr. Summit Shah Discusses Recent Findings on Food Allergies and Exercise-Induced Anaphylaxis
8. Safe Composting Tips for People With Food Allergies
9. Exposure Therapy May Be Option for Kids Egg, Milk Allergies
10. People with allergies may have lower risk of brain tumors
11. Options Increasing for Coping With Kids Food Allergies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/6/2016)... ... 2016 , ... Research has shown that building shame resilience ... and level of relapse. , At the 2016 iaedp Symposium, the ... the critical tasks of the recovery phase and beyond including relapse prevention and ...
(Date:2/5/2016)... ... February 05, 2016 , ... Love is in the ... a variety of colors, assortments and packaging. This staple for Valentine’s Day is a ... location. , For Valentine’s Day, not only are long-stem roses available, but also ...
(Date:2/5/2016)... City, UT (PRWEB) , ... February 05, 2016 , ... ... Whole-Food Nutrition , announced that the much-anticipated feature with author Jahnavi Foster, specialist in ... Humans Amateur TV Network. , Each week, on his weekly Whole-Food Warrior TV show, ...
(Date:2/5/2016)... ... February 05, 2016 , ... The event is being held ... Event Center in Minneapolis, Minn. Triumph Over Parkinson’s will fund nearly $100,000 for research ... Schneiderman’s Furniture, lives with Parkinson’s disease and is the architect of this informative event ...
(Date:2/5/2016)... Santa Rosa, CA (PRWEB) , ... February 05, ... ... are pleased to announce the addition of micro-needling services in their Napa Valley ... appearance. The founders of Plastic Surgery Associates, Dr. Canales and Dr. Furnas, are ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)... 2016 Wegener Polyangiitis - Pipeline Review, ... ,Wegener Polyangiitis - Pipeline Review, H2 2015, provides ... This report provides comprehensive information on the ... analysis at various stages, therapeutics assessment by drug ... (RoA) and molecule type, along with latest updates, ...
(Date:2/4/2016)... -- Omnicell, Inc. (NASDAQ: OMCL ), a leading provider of ... announced results for its fiscal year and fourth quarter ... --> GAAP results: Revenue for the fourth quarter ... 4.1% from the third quarter of 2015, and up ... 2014. Revenue for the year ended December 31, 2015 was ...
(Date:2/4/2016)... 2016  Blueprint Medicines Corporation (NASDAQ: BPMC ... selective investigational kinase medicines for patients with genomically ... board of directors of Lonnel Coats , ... of industry-related experience. Jeffrey Albers ... strong strategic experience developing and commercializing numerous oncology ...
Breaking Medicine Technology: