Navigation Links
Follow-up tests improve colorectal cancer recurrence detection
Date:1/14/2014

Among patients who had undergone curative surgery for primary colorectal cancer, the screening methods of computed tomography and carcinoembryonic antigen each provided an improved rate of surgical treatment of cancer recurrence compared with minimal follow-up, although there was no advantage in combining these tests, according to a study in the January 15 issue of JAMA.

Colorectal cancer is the third most common cancer worldwide, with 1.24 million cases reported to the International Agency for Research on Cancer in 2008. Traditionally, patients who have had curative surgery for colorectal cancer undergo regular follow-up for at least 5 years to detect recurrence, a common practice based on limited evidence, according to background information in the article.

John N. Primrose, M.D., F.R.C.S., of the University of Southampton, England, and colleagues assessed detection of recurrence using two common screening methods: measurement of blood carcinoembryonic antigen (CEA; a glycoprotein used as a tumor marker), and computed tomography (CT). They randomized 1,202 patients from 39 hospitals in England to 1 of 4 groups: CEA only (n = 300), CT only (n = 299), CEA+CT (n = 302), or minimum follow-up (n = 301).

Cancer recurrence was detected in 199 participants (16.6 percent) during the period of observation for recurrence (average 4.4 years), and 5.9 percent of participants with recurrence underwent surgery for cure (recurrence detected early enough via follow-up test that surgery can still be performed for cure). The researchers found that surgical treatment of recurrence with curative intent was higher in each of the 3 more intensive follow-up groups compared with the minimum follow-up group. Compared with minimum follow-up, the absolute difference in the number treated with curative intent in the CEA group was 4.4 percent, 5.7 percent in the CT group, and 4.3 percent in the CEA+CT group.

The number of deaths was nonsignif
'/>"/>

Contact: John N. Primrose
j.n.primrose@soton.ac.uk
The JAMA Network Journals
Source:Eurekalert

Page: 1 2

Related medicine news :

1. The doctor will text you now: Post-ER follow-up that works
2. Five-Year Follow-Up Data on CERAMENTâ„¢
3. BONE VOID FILLER Demonstrates Long-Term Safety and Long-Lasting Bone Mineral Density Improvement in Osteoporotic Patients
4. Children with elevated blood pressure dont get recommended follow-up, few at risk for hypertension
5. Ten-Year Follow-Up by AGH Doctors Confirms Effectiveness of Less-Invasive Surgery for Women With Early Stage Breast Cancer
6. New York City successfully locates HIV-positive patients lost to follow-up
7. Nephrologist follow-up improves mortality of severe acute kidney injury patients
8. Chernobyl follow-up study finds high survival rate among young thyroid cancer patients
9. Follow-Up Care After Chest Pain Called Crucial
10. Evidence shows concussions require long-term follow-up for players
11. 5-year follow-up - over half of all ACL reconstructions could be avoided
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... Moffitt Cancer Center researchers say clinical trials for ... leukemia (AML) are very promising. Patients treated with ... and daunorubicin, are showing better responses than patients ... , "Acute myeloid leukemia is an aggressive ... success, especially in older patients," explained Jeffrey Lancet, ...
(Date:4/23/2014)... The American Society for Radiation Oncology (ASTRO) has ... Radiation Therapy for Endometrial Cancer: An ASTRO Evidence-Based ... therapy in the treatment of endometrial cancer. The ... 2014 issue of Practical Radiation Oncology ... The full-length guideline is available as an open-access ...
(Date:4/23/2014)... novel compound that targets an important brain receptor has ... behaviors, including relapse behavior, a University at Buffalo animal ... that this may be a novel lead compound for ... The UB research was published as an online preview ... the study, the compound, RO5263397, severely blunted a broad ...
(Date:4/23/2014)... accessible detection methods that can rapidly screen a ... single cell inside that population has been seriously ... , In the Royal Society of Chemistry journal ... he and his coworkers have developed a novel ... protein ( Chem. Sci. , 2014, DOI: 10.1039/C4SC00578C, ...
(Date:4/23/2014)... Ill. - In a country as wealthy as the United ... 12 seniors do not have access to adequate food due ... food insecure. , Recent research at the University of ... Survey (NHANES) revealed that the seniors who are dealing with ... , "In 2011, 8.35 percent of Americans over age 60 ...
Breaking Medicine News(10 mins):Health News:Moffitt Cancer Center's phase 3 study may be game-changer for acute myeloid leukemia 2Health News:ASTRO issues guideline on the role of postoperative radiation therapy for endometrial cancer 2Health News:ASTRO issues guideline on the role of postoperative radiation therapy for endometrial cancer 3Health News:Novel compound halts cocaine addiction and relapse behaviors 2Health News:Following a protein's travel inside cells is key to improving patient monitoring, drug development 2Health News:More Americans in their golden years are going hungry 2
... Florida have discovered a key gene that, when turned off, ... findings suggest that a combination of agents now being tested ... on, providing a much-needed therapy for the difficult-to-treat cancer. ... of kidney cancer, accounts for just 3 percent of all ...
... is available in French . Montreal, May 20, ... at the Montreal Heart Institute (MHI) by Dr. Jean-Claude Tardif are ... Tardif is a cardiologist and director of the MHI Research Centre, ... holder of the atherosclerosis research chair at the Universit de Montral. ...
... swarm. Even amoebae clump together in mystifyingly clever constellations. ... the cellular and molecular level to bring about this ... organisms into groups. It,s a choreography seen throughout nature ... as precise as the dance lineup of a Broadway ...
... ... Park Association (NRPA) is reminding Americans to take the proper steps to ensure that their ... The Dirty Dozen, a comprehensive brochure and playground-safety resource for playground managers, parents and caregivers. ... Ashburn, VA (Vocus) ...
... live inside every person that team plans to sequence ... effort to map out the genetic composition of hundreds ... first results: scientists report they have completed the genome ... , Found in such places as the gastrointestinal tract, ...
... ... 25 New York Verdicts of 2009. Applied Forensics is a 21st Century Forensics Laboratory ... ... Forensics LLP, a laboratory specializing in handwriting analysis, played an integral role in one ...
Cached Medicine News:Health News:Mayo Clinic researchers find gene they believe is key to kidney cancer 2Health News:Mayo Clinic researchers find gene they believe is key to kidney cancer 3Health News:Patients at high risk of recurrences of heart disease: Breakthrough in prevention 2Health News:Scientists discover the molecular heart of collective behavior 2Health News:Scientists discover the molecular heart of collective behavior 3Health News:Scientists discover the molecular heart of collective behavior 4Health News:Spring into Summer with The Dirty Dozen Guide to Playground Safety 2Health News:Spring into Summer with The Dirty Dozen Guide to Playground Safety 3Health News:Scientists Map Genetic Codes of Human Microbes 2Health News:Scientists Map Genetic Codes of Human Microbes 3Health News:Verdict Search recognizes Applied Forensics in Top 25 New York Verdicts of 2009 2
(Date:1/14/2014)... Calif. , Jan. 14, 2014 The Brandeis Medical Center, ... Angeles a premier and affordable laser tattoo removal experience ... Dr. Brandeis, focus is in providing high quality cosmetic services with ... patients. " Southern California has seen ...
(Date:1/14/2014)... Animal Emergency Critical Care, a LifeCentre partner practice, located at ... is the first in Loudoun County to ... Susan M. Barnes , Medical Director, is a well-seasoned veterinarian ... Cole Taylor , are avid scuba divers. "As altitude skiers and ...
(Date:1/14/2014)... , Jan. 14, 2014   Oligomerix, Inc. , a privately ... for Alzheimer,s disease (AD) and related neurodegenerative disorders, announced ... Valhalla, NY as of January 15, ... at New York Medical College. Oligomerix, which ...
Breaking Medicine Technology:Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2Hyperbaric Veterinary Medicine (hvm) Announces Animal Emergency Critical Care Installs A Small Animal Hyperbaric Chamber 2Oligomerix Relocates Corporate Headquarters and Secures Additional Laboratory Space from New York Medical College 2
... ALISO VIEJO, Calif., April 7, 2011 Avanir Pharmaceuticals, ... data from a number of clinical research activities will be ... of Neurology (AAN), taking place in Honolulu, HI, at the ... details about the data presentations:Title: Burden of Pseudobulbar Affect on ...
... Texas, April 7, 2011 Luminex Corporation (Nasdaq: ... Excellence Award in the category of In Vitro Diagnostics ... is a compact, versatile laboratory analysis platform designed to ... from a single sample. (Logo:   http://photos.prnewswire.com/prnh/20100104/LUMINEXLOGO ...
Cached Medicine Technology:Avanir Pharmaceuticals to Present Data at the American Academy of Neurology Annual Meeting 2Avanir Pharmaceuticals to Present Data at the American Academy of Neurology Annual Meeting 3Avanir Pharmaceuticals to Present Data at the American Academy of Neurology Annual Meeting 4Luminex Corporation Wins Prestigious Medical Design Excellence Award 2Luminex Corporation Wins Prestigious Medical Design Excellence Award 3
Image Diagnostics' Aspect100U is specifically designed for ease of use and high quality image outcome during urological procedures. Aspect tables benefit from a trim, lightweight design, ensuring a s...
The design of this table top is based on advanced functionality for specific urological requirements. This composite product sets a new standard for urological imaging....
... A revolutionary urological imaging ... benefits that translate into improved ... x 1k imaging technology physicians ... to see more anatomical detail ...
Drew Scientific has been making leading edge and top quality CBC systems for over 15 years.,The Excell 16/18 offers a reliable alternative for a 3 part differential....
Medicine Products: