Navigation Links
Follow-up program helps detect melanoma earlier in high-risk patients
Date:1/17/2011

A follow-up program for patients at high risk of developing skin cancer appears to be associated with the detection of melanomas at early stages and with good prognosis, according to a report posted online today that will appear in the May print issue of Archives of Dermatology, one of the JAMA/Archives journals.

Efforts to improve melanoma prognosis have focused on identifying and closely monitoring individuals at high risk, according to background information in the article. "Fair-skinned persons, persons who tan with difficulty, blond or red-haired persons and persons with blue eyes have more risk of developing melanoma than the general population," the authors write. "The presence of many pigmented lesions, including freckles and clinically typical or atypical nevi; intermittent sun exposure and severe sunburns, especially during childhood; and exposure to artificial UV-A radiation have all been associated with an increased risk of melanoma." Individuals with a personal or family history of melanoma are also at high risk.

Dermoscopya noninvasive diagnostic technique in which a clinician performs a microscopic evaluation of a skin lesionimproves the accuracy of melanoma diagnoses, the authors note. Gabriel Salerni, M.D., of Hospital Clinic of Barcelona, Institut d'Investigacions Biomdiques August Pi I Sunyer, Barcelona, and colleagues analyzed data from 201 patients diagnosed with melanoma in one specialized unit, including 40 who were in a follow-up program for high-risk individuals and 161 who were referred for evaluation by another clinician. All melanomas diagnosed among these patients were evaluated by dermoscopy.

Most of the melanomas diagnosed in the follow-up program did not match clinical or dermoscopic features characteristic of melanoma. For example, only 12 percent fulfilled all four ABCD criteria outlined for melanoma detectionasymmetry (A), uneven borders (B), colors (C) and differential dermoscopic structures (D). This compares with 63.6 percent of the melanomas detected among individuals referred to the institution but not in the follow-up program.

In addition, 70 percent of melanomas diagnosed in the follow-up group were in situ (had not spread beyond the initial site), compared with 27.9 percent of those in the referred group. The Breslow indexa measure of tumor thicknesswas also lower among the melanomas diagnosed through the follow-up program. The follow-up cancers also tended to be diagnosed at earlier stages: 70 percent were diagnosed at stage zero and 30 percent at stage IA. Among the referral group, 27.9 percent were diagnosed at stage zero, 37.6 percent at stage IA, 12.7 percent at stage IB, 10.9 percent at stage II, 8.5 percent at stage III and 2.4 percent at stage IV.

"The inclusion of patients who are high risk for melanoma in follow-up programs allows the detection of melanoma in early stages, with good prognosis, even in the absence of clinical and dermoscopic features of melanoma," the authors conclude. "In the general population without specific surveillance, melanoma continues to be diagnosed at more advanced stages. Our findings suggest that current efforts in public and medical education might have no substantial effect in this group. Further strategies and educational programs may be needed to improve the early detection of these lesions. We believe that high-risk individuals, whenever proper resources are available, should be referred to melanoma centers or qualified institutions for regular follow-up."


'/>"/>

Contact: Susana Puig, M.D.
spuig@clinic.ub.es
JAMA and Archives Journals
Source:Eurekalert

Related medicine news :

1. Blacks Less Likely to Get Follow-Up Colon Screening
2. Acne Patients Happy With Online Follow-Up Care
3. Hospitals Falling Short on Heart Patients Follow-Up Care
4. Falls and follow-ups: Medical attention following a fall critical to senior health
5. Lymphoma Survivors Often Miss Out on Follow-Up
6. Results of the placement of multiple endoscopic stents for postoperative biliary strictures remains excellent after long-term follow-up
7. Conventional, annual Pap smear cost-effective follow-up after cervical lesion treatment
8. Follow-ups prove powerful tool for treating depression in primary care
9. Time to Get Focused at Exploration Summer Programs
10. Medical Training School, Pima Medical Institute Offering First Bachelor's Degree Program
11. TV drama can be more persuasive than news program, study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... ... The temporary closing of Bruton Memorial Library on June 21 due to a possible lice ... overlooked aspect of head lice: the parasite’s ability to live away from a human host, ... a necessary one in the event that lice have simply gotten out of control. , ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as ... City area —Johnson is one of the first doctors to perform the treatment. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may suffer ... unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid ... healthy coping following a traumatic event. , Trauma sufferers tend to feel a range ...
(Date:6/24/2016)... Fla. (PRWEB) , ... June 24, 2016 , ... Global ... Trend magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this recognition ... Florida. , Seven Greenberg Traurig Shareholders received special honors as members of this year’s ...
(Date:6/24/2016)... ... ... People across the U.S. are sharpening their pencils and honing their writing skills ... patients and their families pay tribute to a genetic counselor by nominating him or ... Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, Genome magazine ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research and ... Global Market - Forecast to 2022" report to their ... treatment method for the patients with kidney failure, it replaces ... fluid from the patient,s blood and thus the treatment helps ... and chloride in balance. Increasing number of ...
(Date:6/23/2016)... 2016  In a startling report released today, National Safety ... lacking a comprehensive, proven plan to eliminate prescription opioid overdoses. ... how states are tackling the worst drug crisis in recorded U.S. ... Kentucky , New Mexico , ... Of the 28 failing states, three – Michigan ...
(Date:6/23/2016)... ANGELES , June 23, 2016 ... CAPR ), a biotechnology company focused ... therapeutics, today announced that patient enrollment in its ... in Duchenne) has exceeded 50% of its 24-patient ... enrollment in the third quarter of 2016, and ...
Breaking Medicine Technology: