Navigation Links
Fluoride Treatment of Synthetic Bio-material Assists Dental Bone Regeneration

Lawrence, KS (PRWEB) May 03, 2013

Journal of Oral Implantology – For a successful dental implant, a sufficient amount of jawbone is necessary. Deficient bone must be built up before the procedure. Guided bone regeneration is a common treatment, and bio-materials treated with fluoride are displaying cell proliferation that can improve this process.

The Journal of Oral Implantology reports on a study of bio-resorbable synthetic hydroxyapatite granules used as a bone supplement material. When these granules were exposed to a 4 percent sodium fluoride solution, cell proliferation was increased.

Bone regeneration techniques include the use of artificial materials such as hydroxyapatite and tricalcium phosphate. Implant products are being made with surface coatings or textures that have a biological effect on protein attachment and cell proliferation. When fluoride is added to this surface, it activates osteoblastic, or bone-making, cells and increases the rate of bone regeneration.

In this study, hydroxyapatite granules were treated with a neutral 4 percent sodium fluoride solution. This led to the formation of a reactant resembling calcium fluoride on the surface of the granules. Immediate but slow release of fluoride came from the granules, and the concentration increased over time. Migration of human osteoblast-like MG-63 cells was confirmed when compared to a nonfluoridated control sample.

Fluoride concentrations of 1.0-2.0 parts per million (ppm) showed this positive effect. When the concentration reached 5.0 ppm, however, the opposite effect was observed—the fluoride significantly inhibited cell proliferation.

The authors conclude that the fluoride solution stimulates bone regeneration. The slow release of fluoride from hydroxyapatite granules facilitates osteogenesis, making this a beneficial method to supply fluoride and promote cell proliferation.

Full text of the article, “Fluoride-Treated Bio-Resorbable Synthetic Hydroxyapatite Promotes Proliferation and Differentiation of Human Osteoblastic MG-63 Cells,” Journal of Oral Implantology, Vol. 39, No.1, 2013, is available at


About Journal of Oral Implantology
The Journal of Oral Implantology is the official publication of the American Academy of Implant Dentistry and of the American Academy of Implant Prosthodontics. It is dedicated to providing valuable information to general dentists, oral surgeons, prosthodontists, periodontists, scientists, clinicians, laboratory owners and technicians, manufacturers, and educators. The JOI distinguishes itself as the first and oldest journal in the world devoted exclusively to implant dentistry. For more information about the journal or society, please visit:

Media Contact:
Bridget Lamb
Allen Press, Inc.
800/627-0326 ext. 248

Read the full story at

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. Removing Fluoride: What's the Fuss?
2. Zion Health’s Native Remedy-Natural Clay Toothpaste without Fluoride; Now Available at Marquette Food Co-op
3. Zion Health Announces Native Remedy-Natural Clay Toothpaste without Fluoride formulated to help Prevent Gum Disease. Now Available At Whole Foods Market in Lafayette, CA.
4. Jacksonville, FL Periodontist, Dr. Richard E. Aguila, Offers Laser Gum Disease Treatment
5. Girls With Autism May Need Different Treatments Than Boys
6. Large genomic study identifies endometrial cancer subtypes, treatment opportunities
7. Women's Excellence in Menopause Now Offering Treatment Options for Decreased Sex Drive near Rochester Hills, Michigan; Natural Therapy Available via Bioidentical Hormones
8. Gastric bypass findings could lead to diabetes treatment
9. Into Action Drug Treatment Center Supports the March of Dimes Walk
10. Alzheimer's Treatment Clinical Trial Receives Clearance
11. Atlantic Spine Center Announces Updated Web Content on Spinal Stenosis New Treatments and a Better Approach to Spinal Stenosis Surgery
Post Your Comments:
(Date:11/24/2015)... ... November 25, 2015 , ... Genesis Chiropractic Software helps practice ... an agreement between the practice owner and the patient that automatically manages all ... projections. Click here to learn more. , According to ...
(Date:11/24/2015)... , ... November 24, 2015 , ... Charitable giving is ... donations are made in the last five weeks of the year totalling over $358 ... in 2012 to connect the nation’s charities with those individuals who want to “give ...
(Date:11/24/2015)... IL (PRWEB) , ... November 24, 2015 , ... ... are national leaders when it comes to several aspects of orthopedic care. They ... joint replacements, orthopedic surgeries and general orthopedic care. , Becker's Hospital Review ...
(Date:11/24/2015)... ... November 24, 2015 , ... In response to recent news highlighting ... from prescription opioids in the United States grew 400 percent between 1999 and 2010, ... were involved in 37 percent of all fatal drug overdoses. (1) , While oxycodone ...
(Date:11/24/2015)... (PRWEB) , ... November 24, 2015 , ... Serenity Point ... a series of recent video interviews with some of the staff members at their ... the residential treatment facility, as well as some of the things that make their ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... Nov. 24, 2015  Natera, Inc. (Nasdaq: ... genetic testing and the analysis of circulating ... present at the 27 th  Annual Piper ... 2015 at 1:00 p.m. ET.  Matthew Rabinowitz, Ph.D., CEO of ... business activities and financial outlook. ...
(Date:11/24/2015)... York , 24 de noviembre de 2015 ... Avery Breathing Pacemaker System, se complace anunciar el ... como consultor clínico.   ... Foto -   ... es un fisiólogo y consultor en neonatología y ...
(Date:11/24/2015)... Connecticut , November 24, 2015 ... of Acadiana has entered into a multi-year agreement ... imaging centers. This investment will provide the Breast Center ... --> Sectra (STO: SECT B) announces that ... agreement to deploy Breast Imaging PACS in its ...
Breaking Medicine Technology: