Navigation Links
Fluoride Treatment of Synthetic Bio-material Assists Dental Bone Regeneration

Lawrence, KS (PRWEB) May 03, 2013

Journal of Oral Implantology – For a successful dental implant, a sufficient amount of jawbone is necessary. Deficient bone must be built up before the procedure. Guided bone regeneration is a common treatment, and bio-materials treated with fluoride are displaying cell proliferation that can improve this process.

The Journal of Oral Implantology reports on a study of bio-resorbable synthetic hydroxyapatite granules used as a bone supplement material. When these granules were exposed to a 4 percent sodium fluoride solution, cell proliferation was increased.

Bone regeneration techniques include the use of artificial materials such as hydroxyapatite and tricalcium phosphate. Implant products are being made with surface coatings or textures that have a biological effect on protein attachment and cell proliferation. When fluoride is added to this surface, it activates osteoblastic, or bone-making, cells and increases the rate of bone regeneration.

In this study, hydroxyapatite granules were treated with a neutral 4 percent sodium fluoride solution. This led to the formation of a reactant resembling calcium fluoride on the surface of the granules. Immediate but slow release of fluoride came from the granules, and the concentration increased over time. Migration of human osteoblast-like MG-63 cells was confirmed when compared to a nonfluoridated control sample.

Fluoride concentrations of 1.0-2.0 parts per million (ppm) showed this positive effect. When the concentration reached 5.0 ppm, however, the opposite effect was observed—the fluoride significantly inhibited cell proliferation.

The authors conclude that the fluoride solution stimulates bone regeneration. The slow release of fluoride from hydroxyapatite granules facilitates osteogenesis, making this a beneficial method to supply fluoride and promote cell proliferation.

Full text of the article, “Fluoride-Treated Bio-Resorbable Synthetic Hydroxyapatite Promotes Proliferation and Differentiation of Human Osteoblastic MG-63 Cells,” Journal of Oral Implantology, Vol. 39, No.1, 2013, is available at


About Journal of Oral Implantology
The Journal of Oral Implantology is the official publication of the American Academy of Implant Dentistry and of the American Academy of Implant Prosthodontics. It is dedicated to providing valuable information to general dentists, oral surgeons, prosthodontists, periodontists, scientists, clinicians, laboratory owners and technicians, manufacturers, and educators. The JOI distinguishes itself as the first and oldest journal in the world devoted exclusively to implant dentistry. For more information about the journal or society, please visit:

Media Contact:
Bridget Lamb
Allen Press, Inc.
800/627-0326 ext. 248

Read the full story at

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. Removing Fluoride: What's the Fuss?
2. Zion Health’s Native Remedy-Natural Clay Toothpaste without Fluoride; Now Available at Marquette Food Co-op
3. Zion Health Announces Native Remedy-Natural Clay Toothpaste without Fluoride formulated to help Prevent Gum Disease. Now Available At Whole Foods Market in Lafayette, CA.
4. Jacksonville, FL Periodontist, Dr. Richard E. Aguila, Offers Laser Gum Disease Treatment
5. Girls With Autism May Need Different Treatments Than Boys
6. Large genomic study identifies endometrial cancer subtypes, treatment opportunities
7. Women's Excellence in Menopause Now Offering Treatment Options for Decreased Sex Drive near Rochester Hills, Michigan; Natural Therapy Available via Bioidentical Hormones
8. Gastric bypass findings could lead to diabetes treatment
9. Into Action Drug Treatment Center Supports the March of Dimes Walk
10. Alzheimer's Treatment Clinical Trial Receives Clearance
11. Atlantic Spine Center Announces Updated Web Content on Spinal Stenosis New Treatments and a Better Approach to Spinal Stenosis Surgery
Post Your Comments:
(Date:12/1/2015)... ... December 01, 2015 , ... For many X-rays taken ... for accurate interpretation by the radiologist. The marking utensils are so small, however, ... has found a way to alleviate this problem. , He developed the patent-pending ...
(Date:12/1/2015)... ... ... McLean, VA., December 1, 2015 - Octo Consulting Group, ... development contract to support the National Geospatial-Intelligence Agency's (NGA) IT Services Directorate. ... as well as operations and sustainment support to the NGA’s Agile Web Presence ...
(Date:12/1/2015)... GA (PRWEB) , ... December 01, 2015 , ... ... supports SACC-GA and SACC-USA through membership and leadership since 2008. Gary ... Chair for SACC-USA . Gary has spent a significant amount of time ...
(Date:12/1/2015)... Chicago, IL (PRWEB) , ... December 01, 2015 ... ... the Unified Contact Center Enterprise Authorized Technology Provider (ATP) status from Cisco. This ... sell, deploy and support Cisco Unified Contact Center solutions targeted to the high-end ...
(Date:11/30/2015)... ... December 01, 2015 , ... ... as a 2015-2016 inductee into its VIP Woman of the Year Circle. ... the nation’s leading networking organization exclusively for professional women, boasting 850,000 members and ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... Sweden , December 1, 2015 ... Cancer Study Group (IBCSG, Bern ) and ... to be part of a state of the art trial, ... --> --> The study, ... treated with anti-hormonal therapy in combination with palbociclib, a cancer ...
(Date:11/30/2015)... BASEL, Switzerland , Dec. 1, 2015 ... through its wholly-owned UK subsidiary Proximagen Ltd., today announced ... novel, oral small molecule inhibitor of Vascular Adhesion Protein ... in the treatment of inflammatory disease. The VAP-1 inhibitor ... --> --> Under the terms ...
(Date:11/30/2015)... Asia,s largest exhibition and conference dedicated to the Medical Device ... 22 nd April 2016. --> --> ... --> -->   --> --> ... population and the government back up, the Medical Device is one of the ... . With the aging population and the government back up, the Medical ...
Breaking Medicine Technology: