Navigation Links
Fluorescent probes light up cancerous tumors
Date:2/16/2010

tumor, particularly the margins.

In a series of studies, working mainly in mice with implanted human tumors, the researchers showed that if tumors had spread to surrounding tissue, the ACCP-nanoparticle probes enabled them to visualize areas of tumors that they wouldn't ordinarily see either because the tissue was buried beneath other tissue or the tumor simply was difficult to distinguish from normal tissue.

Using a technique called PCR (polymerase chain reaction) to measure tumor DNA, they found that, on average, 90 percent fewer cancer cells remained after surgery to remove tumors in mice using the probe-based molecular guidance compared to surgery without it a 10-fold reduction. They also found that the fluorescently labeled probes hit their mark 93 percent of the time, allowing the researchers to "see" left over tumor tissue.

According to the scientists, only a single injection of the nanoparticle-based probe containing the fluorescent and magnetic tags was needed in order to use MRI to examine the entire mouse model for tumors before and after surgery, in addition to the real-time guidance in surgery.

Nguyen said that in the future, additional tags may be added, and eventually, a cocktail of personalized probes may be designed for individual types of cancers. If the nanoparticle-based probes are successful in finding tumor cells in humans, the researchers envision using them eventually to deliver chemotherapy drugs to finish off the remaining cancer.

Tsien and Nguyen see many advantages to molecularly guided cancer surgery. Probes can be useful in staging cancer, particularly in prostate cancer, and can be used in a variety of tumor types. In addition, such biological probes can be used in laparoscopic and robotic surgery, where surgeons cannot feel the tumor, and rely much more on sight. If surgeons can completely remove a cancer, it may mean a patient could be cured quickly, and at relatively low cost when
'/>"/>

Contact: Steve Benowitz
sbenowitz@ucsd.edu
619-543-6163
University of California - San Diego
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Fluorescent probes may permit monitoring of chemotherapy effectiveness, Stanford study shows
2. Naturally fluorescent molecules may serve as cancer biomarker
3. MBL scientist Osamu Shimomura wins Nobel Prize for discovery of green fluorescent protein
4. Fluorescent Retinal Cells Warn of Eye Disease
5. MEDRAD Multi Vendor Service Launches TotalRepair(SM) on Select Ultrasound Probes
6. Nanoscopic probes can track down and attack cancer cells
7. China Medical Technologies Announces the Receipt of SFDA Approval for Two of its FISH Probes and the Approval for the Hi-Tech Enterprise Status for its PRC Subsidiaries
8. Team probes why climbers die on Mount Everest
9. Study Probes Why Smokers Find It Hard to Quit
10. Study Probes Internet Health-Related Search Patterns
11. String probes for devastating childhood digestive disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... -- Researchers from The Miriam Hospital have found ... who are also depressed have difficulty sticking to ... particularly true for women, and screening and brief ... of treatment. The study and its findings are ... , Chronic obstructive pulmonary disease is a ...
(Date:7/9/2014)... world have been linked to an emerging fungal ... National Institute for Mathematical and Biological Synthesis (NIMBioS) ... , In a series of mathematical models, ... of internal organs in frogs, could cause extinction ... are exposed to the virus every few years, ...
(Date:7/9/2014)... A retrospective study conducted by researchers at Tufts University ... adults with intellectual and developmental disabilities, the likelihood of ... dental care increased. The findings, published in the July/August ... help improve interventions designed to address the oral health ... reviewed the dental records of 107 patients at one ...
(Date:7/9/2014)... dramatically in Western societies. One frequently cited reason is ... fewer infections than previous generations, thereby delaying maturation of ... Sahlgrenska Academy, University of Gothenburg, monitored children until the ... system in relation to allergic disease. All of the ... Region, half of them on farms that produced milk.,Lower ...
(Date:7/8/2014)... A team of clinicians from Plymouth, UK, and Sydney, ... 10th July Australia) launched ACEmobile - a free-to-use app ... , ACEmobile is the first of its kind; an ... tool provides support through the whole process, meaning more ... out this type of assessment. Designed by clinicians for ...
Breaking Medicine News(10 mins):Health News:Miriam Hospital study examines effect of depressed mood on pulmonary rehab completion 2Health News:Study predicts ranavirus as potential new culprit in amphibian extinctions 2Health News:Adults with special needs see gains, challenges with long term oral care 2Health News:Adults with special needs see gains, challenges with long term oral care 3Health News:New app widens opportunities for dementia assessments 2Health News:New app widens opportunities for dementia assessments 3
... Oct. 15 With the Centers for Disease Control and ... now spread throughout the United States, the American Red Cross ... or are taking care of someone who has the flu. ... person to person in droplets of coughs or sneezes, and ...
... 15 Americans without health insurance are one major illness ... research by the Kellogg School of Management at Northwestern University ... major health concern, such as heart disease, cancer or a ... in order to pay their medical expenses. , ...
... a Medical College of Georgia resident and faculty member may ... circumstances. About 2 percent of patients that undergo the ... performed in an emergency situation or prior to surgery. ... and uses a metal scope to open the mouth and ...
... Smoking bans are effective at reducing the risk of ... secondhand smoke, says a new report from the Institute ... sufficient evidence that breathing secondhand smoke boosts nonsmokers, risk ... even relatively brief exposures could lead to a heart ...
... Past President of the New Jersey Obstetrical and Gynecological Society ... 15 According to NAMS (North American Menopause Society), 6,000 ... a year. For the majority of women, hot flashes, ... For years, women have searched for a treatment that ...
... beautifully clear, acne-free skin, naturally? Skip the synthetics and ... Bees(®) Natural Acne Solutions(TM) products. , To view the ... , (Photo: http://www.newscom.com/cgi-bin/prnh/20091015/NY92770 ) ... truly natural* acne line clinically proven to help ...
Cached Medicine News:Health News:Red Cross Offers Important Tips for Caring for Someone With the Flu 2Health News:Red Cross Offers Important Tips for Caring for Someone With the Flu 3Health News:The Effects of Health on Wealth: New Study Reveals Individuals Without Health Insurance at Risk for 'Financial Catastrophe' 2Health News:The Effects of Health on Wealth: New Study Reveals Individuals Without Health Insurance at Risk for 'Financial Catastrophe' 3Health News:New laryngoscope could make difficult intubations easier 2Health News:Smoking bans reduce the risk of heart attacks associated with secondhand smoke 2Health News:On World Menopause Day, October 18, The International Menopause Society and World Health Organization Urge Women to Learn About Their Options for Dealing With Menopause 2Health News:On World Menopause Day, October 18, The International Menopause Society and World Health Organization Urge Women to Learn About Their Options for Dealing With Menopause 3Health News:Video: Introducing Natural Acne Solutions(TM) By Burt's Bees(R) 2
(Date:1/15/2014)...  Humberto C. Antunes,  Galderma  worldwide CEO, will receive a ... of Drugs in Dermatology (JDD) at the upcoming ... is January 17-20, 2014, at the Omni Orlando Resort at ChampionsGate ... The ODAC is a distinguished event that delivers a ...
(Date:1/15/2014)...  In an unprecedented effort to curb the spread of "superbugs" such ... vehicles, an advanced and portable UV germicidal lamp manufactured by MRSA-UV ... In order to prevent EMS paramedics and transport ... West Palm Beach Fire Rescue is the first in ...
(Date:1/15/2014)... Inc. (Nasdaq: ECTE ) ("Echo"), a medical ... non-invasive, wireless continuous glucose monitoring system, today announced that ... CEO of Echo Therapeutics, will present at "TEN", Noble ... Mr. Doman will make a corporate presentation to ...
Breaking Medicine Technology:Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 4Superbugs No Longer Ride In Rescue Vehicles 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 3
... 17 The following letter is being released ... , Dear Fellow Shareholders: , We are pleased to report to you ... ever. During this difficult time we were able to complete and validate ... being able to manufacture Multikine for the Phase III clinical trial.  We ...
... , RALEIGH, N.C. , Feb. ... training solutions for the pharmaceutical and biotech industry, today announced ... and Retail Pharmacy .  The courses, developed in partnership ... to the company,s Managed Markets Excellence® Series, a ...
Cached Medicine Technology:CEL-SCI Corporation Releases Letter to Shareholders 2CEL-SCI Corporation Releases Letter to Shareholders 3CEL-SCI Corporation Releases Letter to Shareholders 4CEL-SCI Corporation Releases Letter to Shareholders 5CEL-SCI Corporation Releases Letter to Shareholders 6Pharmaceutical Institute Launches New Training Resources Focused on Employers and Retail Pharmacy 2Pharmaceutical Institute Launches New Training Resources Focused on Employers and Retail Pharmacy 3
... The Aculens 186 UV combines the ... that include measurement of ultra violet transmission ... Velo 186 is also programmed to network ... other VELO Instruments, today, or in the ...
...
...
...
Medicine Products: