Navigation Links
Fluorescent probe for oral cancer
Date:8/4/2010

UC Davis researchers have developed a laser probe for the early detection of oral cancer. A trial with human subjects shows that the device could also be used during surgery to locate the edges of a tumor.

Approximately 43,000 people in the U.S. are diagnosed with tumors of the mouth, pharynx and larynx each year. The main risk factor is smoking, but a recent rise in cases has been linked to human papillomavirus. Most cases are not diagnosed until the cancer has reached an advanced stage.

"There's a lot out there about breast, prostate and brain cancer, but people are not so aware about oral cancer and its devastating consequences," said Laura Marcu, a professor of biomedical engineering at UC Davis. "People don't think to look for it, and there isn't any routine screening."

Marcu's laboratory collaborated with Dr. Gregory Farwell's group in the Department of Otolaryngology at the UC Davis Cancer Center to develop the fiber-optic probe.

The probe stimulates molecules in the patient's tissues with a laser. Some of these molecules naturally respond by re-emitting fluorescent light. The device rapidly detects and analyzes this light using a process called "time-resolved fluorescence spectroscopy" (TR-LIFS), which provides information about the types of molecules present.

During surgery, blood can distort the intensity of the fluorescence signal but not its duration. By using sensitive measurements of the change in fluorescence over time, surgeons can see the tumor margins even as they are cutting the tissue.

Based on encouraging results in animal tests, Marcu and Farwell's team recruited nine human volunteers from among patients who arrived at the UC Davis Medical Center for surgical therapy of the mouth, throat and larynx. They compared readings from spectroscopy with biopsy samples from the same locations and found that the probe could accurately diagnose the cancer in the surgical environment.

The p
'/>"/>

Contact: Andy Fell
ahfell@ucdavis.edu
University of California - Davis - Health System
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Replacing hydrogen in fluorescent dyes improves detection ability, stability and shelf life
2. Fluorescent probes light up cancerous tumors
3. Study Probes Causes of Anger in Returning U.S. Soldiers
4. PET scanning probes reveal different cell function within the immune system
5. Lab that probes genetic clues to disease is poised for major expansion
6. Nanoscale stealth probe slides into cell walls seamlessly, say Stanford engineers
7. Scientists develop the first model for investigating the origins of testicular cancer in humans
8. New imaging technique could help physicians ease the aftermath of breast cancer
9. Scientists develop designer protein, opening new door in cancer research
10. Oral contraceptive use associated with increased risk of breast cancer
11. Purdue-IU team uncovers potential prostate cancer marker
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... (PRWEB) July 30, 2014 Recent ... medical devices have determined Nurse Call Systems to ... legislation, this requires all Nurse Call Systems to ... practice improves patient safety, reduces clinical risks, and ... hospital based Corporate Risk and Clinical Risk Committee ...
(Date:7/29/2014)... Daily Gossip reveals in its review that the Tinnitus Miracle ... eliminate all the symptoms associated to this condition. , ... such as mild hearing loss, as well as headaches. The ... gone forever. , The method will lead to a cure ... says that at the end of the treatment, sufferers will ...
(Date:7/29/2014)... Denver, CO (PRWEB) July 29, 2014 Daily ... method reveals some unique tips to gain beautiful and clear ... some cases, sufferers will see these positive results even sooner ... acne sufferer, Mike Walden, who used this step by step ... suffered from severe acne for years. Mike battled this condition ...
(Date:7/29/2014)... For survivors of severe combat injuries threatening more ... have a good record of safety and effectiveness in ... of Plastic and Reconstructive Surgery , ... of Plastic Surgeons (ASPS). , Experience with multiple ... Afghanistan shows good success rates, with no increase in ...
(Date:7/29/2014)... TUESDAY, July 29, 2014 (HealthDay News) -- Chlorine helps ... swimmers more likely to develop eye infections, doctors say. ... eyes as well as blurry vision, said Dr. Sampson ... Center in New Jersey. It,s important to understand ... pools washes away the outer film layer of the ...
Breaking Medicine News(10 mins):Health News:NiQ Health Reveals the Extensive Use of Unregulated Medical Devices in Australian Hospitals 2Health News:NiQ Health Reveals the Extensive Use of Unregulated Medical Devices in Australian Hospitals 3Health News:NiQ Health Reveals the Extensive Use of Unregulated Medical Devices in Australian Hospitals 4Health News:Tinnitus Miracle Review Exposes the Only Holistic System for Tinnitus Cure 2Health News:Acne No More Review Reveals Most Effective Acne Cure Program 2Health News:Good outcomes with multiple limb salvage after severe combat injuries, reports Plastic and Reconstructive Surgery 2Health News:Protect Your Eyes When Hitting the Pool 2
... in endurance sports, study finds , THURSDAY, June ... to strengthen inhalation muscles and reduce their need ... such as cycling and swimming, a new study ... muscle training (IMT) significantly reduced the amount of ...
... ... Between Sharks and Surfers. , ... (PRWEB) June 3, 2010 -- Surfline thinks it takes more than a week to explain ... in the presence and environment of sharks as surfers. Therefore, Surfline has launched "Shark Month" ...
... what it would be like to go on a mission ... will enter an isolation chamber in Moscow for a simulated ... the Russian Federation Institute for Biomedical Problems (IBMP) of ... schedule full of more than 90 experiments and realistic scenarios, ...
... Study ... ... -- Chemotherapy-induced amenorrhea in premenopausal women being treated for early stage breast cancer was ... the New England Journal of Medicine by the National Surgical Adjuvant Breast and Bowel ...
... Le Cordon ... worldwide “Apéritif à la Française" on June 3rd, 2010 at the Espace Réunion in Montreal, ... ... Ottawa Culinary Arts Institute is proud to announce that it will be one of the ...
... ... for Medical Marijuana Hydroponics Nutrients , ... Seattle, WA (PRWEB) June 3, 2010 -- In a landmark decision, ... hydroponics nutrients., , ,Oregon and most other states have regulatory agencies that ...
Cached Medicine News:Health News:Surfline Launches "Shark Month" Presented by Casio G'zOne 2Health News:520-day Mars mission simulation 2Health News:520-day Mars mission simulation 3Health News:520-day Mars mission simulation 4Health News:Interruption of Menstrual Cycle by Chemotherapy Associated with Improved Survival in Early Breast Cancer 2Health News:Interruption of Menstrual Cycle by Chemotherapy Associated with Improved Survival in Early Breast Cancer 3Health News:Interruption of Menstrual Cycle by Chemotherapy Associated with Improved Survival in Early Breast Cancer 4Health News:Le Cordon Bleu Ottawa to Sponsor Apritif la Franaise in Partnership with Sopexa 2Health News:Hydroponics Nutrients For Medical Marijuana Gain Government Approval 2
(Date:7/29/2014)...  Instrumentation Laboratory (IL) today announced the launch of its ... is part of a comprehensive rebranding effort by Werfen, the ... Boston, MA , in 1959, IL has been part ... companies in the group include Inova Diagnostics ( San ... Spain ).  Like IL, these three companies are focused ...
(Date:7/29/2014)... Research and Markets has announced the addition ... report to their offering. ... medical device used to provide medication or assist a ... achieve adequate oxygen levels to maintain life. Patients with ... ARDS require the need of respiratory devices. The medication ...
(Date:7/29/2014)... , July 29, 2014  Based on its ... (PERS) market, Frost & Sullivan recognizes MobileHelp with ... for Price Performance Value Leadership. MobileHelp,s leadership in ... expectations for tech progression in personal emergency response, ... these solutions. MobileHelp is at the ...
Breaking Medicine Technology:Instrumentation Laboratory Unveils New Corporate Brand 2Instrumentation Laboratory Unveils New Corporate Brand 3Global Respiratory Devices Market 2014-2018 2Frost & Sullivan Applauds MobileHelp for its Targeted Supplies for the PERS Market 2Frost & Sullivan Applauds MobileHelp for its Targeted Supplies for the PERS Market 3
... Horizon Pharma, Inc. announced today that it has filed a registration statement ... a proposed initial public offering of shares of its common stock.  All shares ... by the Company. , , , ... & Company, Inc. and Piper Jaffray & Co. are acting as ...
... Pharmaceuticals (NYSE: WPI ) today announced that ... as Senior Vice President, Global Operations, has been promoted to Executive Vice ... Bisaro , President and Chief Executive Officer of Watson. , ... Mr. Stewart will assume responsibility ...
Cached Medicine Technology:Horizon Pharma, Inc. Files Registration Statement for Proposed Initial Public Offering 2Watson Promotes Robert Stewart to Executive Vice President, Global Operations 2Watson Promotes Robert Stewart to Executive Vice President, Global Operations 3
... in the palm of your hand. OHTS ... IOP readings more meaningful with IOPac - the ... The IOPac is designed for the ... in a portable platform and is the only ...
... a fundus camera which is ... photography with two angles of,view: ... 22 for non-mydriatic photography). You ... 35-mm film,Polaroid film, video tape ...
... MDoffice seamlessly integrates practice ... optimize and simplify office and ... scheduling, charting, billing, accounting and ... providers, facilities and specialties. MDoffice ...
... slit lamp is a ... that is designed with ... and has standard 10X ... design provides increased optical ...
Medicine Products: