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Florida EMS and Fire Vehicles to Stock Cyanokit(R) 5g (hydroxocobalamin for injection) ANTIDOTE ("Cyanokit") for Cyanide Poisoning

- State officials desire quick-response emergency capability to treat

suspected and known cyanide poisoning -

NAPA, Calif., May 29 /PRNewswire/ -- Dey, L.P. today announced that the Florida Department of Health, Office of Emergency Operations, will stock Cyanokit(R) 5g (hydroxocobalamin for injection) ANTIDOTE for Cyanide Poisoning in the State's emergency medical service (EMS) and fire vehicles through a federal grant from the Department of Homeland Security. As the only FDA-approved treatment that can be given to victims of suspected cyanide poisoning, Cyanokit provides emergency first-responders with a critical care medication to treat patients immediately at the scene of a fire or other accident as well as in a hospital emergency room.(1)

Studies have shown that cyanide, a common but often unrecognized toxic chemical found in fire smoke, may play a significant role in causing the deaths of smoke inhalation victims.(2) In the United States, smoke inhalation is responsible for up to 10,000 civilian and firefighter deaths and more than 20,000 injuries annually.(3)(4)

"It is critical that we do whatever we can to enhance the safety of Florida's first response personnel and the victims they care for in emergencies involving potential exposure to cyanide," said Dr. Joe Nelson, State EMS Medical Director. "Because cyanide poisoning acts very quickly, the immediate quick response capability that Cyanokit provides at the scene of an emergency will be critical in treating known or suspected victims of cyanide poisoning. Inclusion of Cyanokit in our EMS and fire vehicles will help protect both our emergency first responders and Florida's citizens."

"Florida's stocking of Cyanokit in its EMS and fire vehicles reflects a recognition by State officials that first responders need to be prepared to treat cyanide poisoning immediately in an emergency," said Carolyn Myers, Ph.D., President of Dey, L.P. "The ability to treat suspected cases of cyanide poisoning at the scene of a fire or other accident gives potential victims a much-needed measure of safety when survival can be measured in minutes."

About Cyanokit(R) 5g (hydroxocobalamin for injection) ANTIDOTE(1)

Cyanokit is indicated for the treatment of known or suspected cyanide poisoning. If clinical suspicion of cyanide poisoning is high, Cyanokit should be administered without delay.

Important Safety Information

Prior to administration of Cyanokit, smoke-inhalation victims should be assessed for: exposure to fire or smoke in an enclosed area; presence of soot around the mouth, nose or oropharynx; altered mental status.

Use caution in the management of patients with known anaphylactic reactions to hydroxocobalamin or cyanocobalamin. Allergic reactions may include: anaphylaxis, chest tightness, edema, urticaria, pruritus, dyspnea, and rash.

Most common adverse reactions (>5%) are transient and include chromaturia (red-colored urine), erythema (skin redness), rash, increased blood pressure, nausea, headache, decreased lymphocyte percent, and injection site reactions. Usage may interfere with some clinical laboratory evaluations.

If the decision is made to administer another antidote with Cyanokit, these drugs should not be administered in the same IV line. The safety of simultaneous administration has not been established.

Please see full Prescribing Information at or call 800-755-5560 and ask for Customer Service.

About Dey, L.P.

Dey, L.P., a subsidiary of Mylan Inc. (NYSE: MYL), is a specialty pharmaceutical company focused on the development, manufacturing and marketing of prescription drug products for the treatment of respiratory diseases, respiratory-related allergies, and emergency care medicine. As the U.S. leader in sales of nebulized respiratory medication, Dey, L.P. puts patients first through its development of innovative and affordable therapies. The Web sites for Dey, L.P. include,,,,, and

Cyanokit is a registered trademark of Merck Sante s.a.s. Cyanokit is distributed exclusively in the United States by Dey, L.P. of Napa, CA.

Media Contacts:

Dey, L.P. Media Line

800-755-5560, ext. 8363


Nicole Arens

Ogilvy Public Relations Worldwide



1 Full Prescribing Information for Cyanokit.

2 "Report of the Investigation Committee into the Cyanide Poisonings of

Providence Firefighters," May 30, 2006.

3 "Cyanide: Understanding the Risk, Enhancing Preparedness, RTI

International," Clinical Toxicology 47-63.

4 Inna Leybell, "Toxicity, Cyanide," Emedicine from WebMD, (last updated May 18, 2006).

Copyright©2008 PR Newswire.
All rights reserved

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