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Florida Breast Cancer Foundation funds UM study of stress management in breast cancer treatment
Date:7/14/2014

uch as five years later.

The study, co-led by Dr. Bonnie Blomberg, a professor of Microbiology and Immunology at the Sylvester Comprehensive Cancer Center, will measure the changes in cortisol levels, check immune responses in cells, and look for decreased inflammation at the RNA level in cells. The new grant research, which began July 1, focuses on the women who show the most elevated levels of distress in the weeks after breast cancer surgery.

"The hope is that these psychoneuroimmunologic (PNI) effects will show us clearly how therapies like relaxation therapy can affect immune system regulation," Antoni said. "Does effective stress management reduce cortisol levels, increase immune function and decrease inflammation early in the course of women's treatment for breast cancer? We expect that women who show the greatest reductions in distress will also show the greatest reductions in inflammatory signaling and the greatest improvements in immune cell functioning over their first year of treatment."

"We know stress management is effective in a 10-week program, and women who only attended half the sessions had the same benefits, so we are testing the idea that five weeks might be enough time," he said. "The 10-week program also helped us focus on the most important things patients need to learn: being able to relax when needed and being able to cognitively process their emotions. We think we can achieve that in less than 10 weeks by using very focused interventions, and that will be more practical in a clinical setting."

"Drs. Antoni and Blomberg's project was evaluated and scored by a panel of both researchers and laypersons who are advocates for breast cancer research," said Russell Silverman, executive director of the Florida Breast Cancer Foundation. "It was recommended to our committee with great enthusiasm, and we feel that this work will have a positive impact on the future of breast cancer treatment."


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Contact: Annette Gallagher
a.gallagher1@umiami.edu
305-284-1121
University of Miami
Source:Eurekalert

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