Berkeley Prenatal and childhood exposure to flame retardant compounds are linked to poorer attention, fine motor coordination and IQ in school-aged children, a finding by researchers at the University of California, Berkeley, that adds to growing health concerns over a chemical prevalent in U.S. households.
The new study, to be published in the Nov. 15 issue of the journal Environmental Health Perspectives, focuses on PBDEs, or polybrominated diphenyl ethers, a class of persistent, endocrine-disrupting compounds widely found in foam furniture, electronics, carpets, upholstery and other consumer products. The chemicals easily leach out into the environment and are inhaled or ingested through dust, then accumulate in human fat cells.
The researchers collected blood samples taken from 279 women during pregnancy or at delivery, and from 272 of the children when they were 7 years old. Analyses of the blood samples were conducted at the U.S. Centers for Disease Control and Prevention (CDC) in Atlanta.
The children participated in a battery of standardized tests when they were 5 and 7 to assess their attention, fine motor coordination and IQ (verbal comprehension, perceptual reasoning, working memory, processing speed). Mothers and teachers also completed assessment questionnaires to help evaluate the children's attention skills and behavior.
"This is the largest and most comprehensive study to date to examine neurobehavioral development in relation to body burden measures of PBDE flame retardants," said study lead author Brenda Eskenazi, Jennifer and Brian Maxwell Professor of Maternal and Child Health and Epidemiology. "We measured PBDEs both in the mothers during pregnancy and in the children themselves. It shows that there is a relationship of in utero and childhood levels to decrements in fine motor function, attention and IQ."
The new findings stem from a longitudinal study, the Center for the Health Assessm
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University of California - Berkeley