Navigation Links
Five UCSF Scientists Elected to National Academy of Sciences
Date:5/4/2009

f cancers and to identify therapeutic strategies.

In the mid 1980s, Hanahan produced some of the first 'oncomice' - mice genetically engineered to develop organ-specific human cancers. He has used the models to investigate the multi-stage pathways that govern tumor formation and progression, and to explore the benefits of targeted therapies, in particular strategies aimed at blocking the growth of blood vessels to tumors, which rely on the blood supply for growth. This approach is known as angiogenesis inhibition.

He discovered, in collaboration with the late Judah Folkman at Harvard Medical School, the "angiogenic switch," which is activated to produce new blood vessels in early stage lesions preceding overt tumors. A current focus of his work is elucidating the "organ of genesis" of tumors, in which multiple cell types assemble with overtly transformed cells to form aberrant, expansive microenvironments of cancer.

Most recently, he and UCSF colleague Gabriele Bergers, PhD reported evidence that angiogenesis inhibitors -- drugs designed to starve tumors or their blood supply -- succeed at first, but then promote more invasive cancer growth in animals. This provocative finding, he says, warrants further study in model systems and in humans to elucidate mechanisms that could in turn lead to strategies for harnessing the drugs more effectively.

He has also used genetically engineered mouse models to investigate mechanisms of self tolerance to the pancreatic beta cells, which are destroyed by the immune system in type I diabetes; he found, for example rare tolerance-inducing cells in the thymus that express the beta-cell specific insulin gene.

As a graduate student, Hanahan developed high efficiency plasmid transformation methods and E. coli strains that have facilitated DNA cloning procedures; his work on E. coli transformation (the production of "competent cells") has facilitated molecular gen
'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved  

0

GOOD

Page: 1 2 3 4 5 6 7 8

Related medicine news :

1. Scientists discover how to improve immune response to cancer at Princess Margaret Hospital
2. Scienceroll.com on Community Sites for Doctors and Scientists
3. Advancements in Integrative Medicine Research to Be Evaluated by Scientists From Leading International Academic Health Centers
4. Scientists From 25 Countries Sequence Cow Genome
5. Scientists Find New Way to Create Stem Cells
6. Reminder: Top Physician-Scientists Discuss State of Cancer Research at Damon Runyon Cancer Research Foundation Symposium
7. Keeping slim is good for the planet, say scientists
8. VirtualScopics Scientists to Present at International Society for Magnetic Resonance in Medicine 17th Scientific Meeting and Exhibition
9. Scientists Spot Stroke Genes
10. OHSU scientists partner with others to form center aimed at combating infectious diseases
11. BIDMC scientists receive creativity awards from Prostate Cancer Foundation
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Five UCSF Scientists Elected to National Academy of Sciences 
(Date:6/19/2013)... block the body,s system for repairing damage to the ... unlikely as it may seem, those compounds are sparking ... driven by a mutation in BRCA, a gene that ... the mutation. The compounds, termed PARP inhibitors, are the ... of Chemical & Engineering News . C&EN is ...
(Date:6/19/2013)... June 19, 2013 North Carolina-based ... organizational changes to advance development of its technologies. ... “To support the advanced development of our product ... to the Company’s management structure and engaged industry ... Company announced that Michael Galiger will serve as ...
(Date:6/19/2013)... Louisiana State University have developed a method for identifying ... on understanding the genetic interaction between single nucleotide polymorphisms ... cancer,s aggressiveness to avoid unnecessary radical treatment. , ... PLOS ONE in April. , According to the ... cancers and 9 percent of cancer deaths. It is ...
(Date:6/19/2013)... DiscountFurnaceFilter.com, the number one solution for homeowner’s indoor ... Saver kit at an exceptional price. The 5-2-1 Compressor Saver ... conditioning unit during start up, saving wear and tear on ... burn out. , The 5-2-1 Compressor Saver works ... less power to start and drastically reduces the rush of ...
(Date:6/19/2013)... (PRWEB) June 19, 2013 Alternatives, a ... some patients to quit using drugs while allowing them ... Jaffe, the founders of Alternatives, believe that abstinence-only approaches ... they enter treatment and that this approach hurts instead ... people in the United States need treatment for addiction ...
Breaking Medicine News(10 mins):Health News:Entegrion Announces Organizational Changes to Support Advanced Product Development 2Health News:Entegrion Announces Organizational Changes to Support Advanced Product Development 3Health News:Moffitt Cancer Center researchers identify genetic variants predicting aggressive prostate cancers 2Health News:Top L.A. Addiction Experts Assert That an Abstinence-Only Approach to Addiction Keeps 85% of Addicts From Seeking Treatment 2Health News:Top L.A. Addiction Experts Assert That an Abstinence-Only Approach to Addiction Keeps 85% of Addicts From Seeking Treatment 3
... , SUNDAY, Aug. 14 (HealthDay News) -- As ... and kids that children with contagious infections, such as ... the appropriate treatment. According to the experts from ... Del., strep throat is just one of several common ...
... PHILADELPHIA (August 15, 2011)Lymphoma is a cancer that affects ... In a subtype of the disease called extranodal lymphoma, ... and tonsils. Patients with extranodal lymphoma of the head ... frequently damages the salivary glands and causes dry mouth, ...
... Calif. - Like fine chefs, scientists are seemingly approaching a ... type of tissue from human embryonic stem cells. You need ... of growth factors, skill and patience, a laboratory tissue culture ... of newly generated cells lurks a big potential problem: Any ...
... 13 (HealthDay News) -- Heat safety needs to be at ... school sports this month, an expert says. "Players and ... heat stroke," Loyola University Health System athletic trainer Jennifer Janczak ... school football players died of heat stroke, according to the ...
... Randy Dotinga HealthDay Reporter , FRIDAY, Aug. ... who undergo prostate removal often suffer more from incontinence ... about possible aftereffects. The findings suggest there,s a ... post-surgery and what actually happens -- and that many ...
... By Dennis Thompson HealthDay Reporter , FRIDAY, ... chat might seem like innovations best suited to passing ... usefulness in helping people with psychological disorders. The ... people with anxiety and depression, according to recent research. ...
Cached Medicine News:Health News:Kids Urged to Take Steps to Avoid Spreading Illness at School 2Health News:IMRT improves outcomes in patients with extranodal lymphoma of the head and neck 2Health News:Stanford discovery may eliminate potentially lethal side effect of stem cell therapy 2Health News:Stanford discovery may eliminate potentially lethal side effect of stem cell therapy 3Health News:Stanford discovery may eliminate potentially lethal side effect of stem cell therapy 4Health News:Many Men Underestimate Prostate Surgery Side Effects 2Health News:Many Men Underestimate Prostate Surgery Side Effects 3Health News:From the Couch to the Computer: A New Take on Therapy 2Health News:From the Couch to the Computer: A New Take on Therapy 3
(Date:6/19/2013)... WHITE PLAINS, N.Y. , June 19, 2013 /PRNewswire/ ... is supporting more than 300 research projects with one ... patients. And in 2013, "Team In Training" (TNT), a ... largest endurance sports training program, is marking its landmark ... LLS invest more than $875 million in research to ...
(Date:6/19/2013)... June 19, 2013  Omnicell, Inc. (NASDAQ: ... and supply management solutions and analytics software for ... the number one overall pharmacy equipment vendor in ... KLAS, a leading independent healthcare research firm, compared ... in its annual rankings. Omnicell also received the ...
(Date:6/19/2013)... , 19. Juni 2013 /PRNewswire/ ... dass mit der Entwicklung von SCS ... Schritt in der Beschichtung mit Parylene ... Vorteile von biokompatiblem Parylene mit antimikrobiellen ... Beseitigung schädlicher Mikroorganismen auf beschichteten medizinischen ...
Breaking Medicine Technology:Celebrating 25 Years and Counting: Leukemia and Lymphoma Society's "Team In Training" Goes the Distance and Beyond for Blood Cancer Patients 2Celebrating 25 Years and Counting: Leukemia and Lymphoma Society's "Team In Training" Goes the Distance and Beyond for Blood Cancer Patients 3Celebrating 25 Years and Counting: Leukemia and Lymphoma Society's "Team In Training" Goes the Distance and Beyond for Blood Cancer Patients 4Celebrating 25 Years and Counting: Leukemia and Lymphoma Society's "Team In Training" Goes the Distance and Beyond for Blood Cancer Patients 5Omnicell Named Top Vendor in 2013 KLAS Pharmacy Automation Equipment Rankings 2Omnicell Named Top Vendor in 2013 KLAS Pharmacy Automation Equipment Rankings 3Omnicell Named Top Vendor in 2013 KLAS Pharmacy Automation Equipment Rankings 4Specialty Coating Systems gibt die Einführung einer neuen antimikrobiellen Parylene-Technologie bekannt 2
... 7 AMN Healthcare Services, Inc. (NYSE: AHS ), ... host its quarterly conference call to discuss third quarter results ... The company also expects to issue an earnings news release ... at approximately 4:00 p.m. Eastern Time. , A live webcast ...
... Dynatronics Corporation (Nasdaq: DYNT ) today announced the appointment ... production and research and development, replacing Ronald Hatch, who has ... management team," said Kelvyn Cullimore Jr., chairman and president of ... our manufacturing operation as well as our research and development ...
Cached Medicine Technology:AMN Healthcare Services to Host 2009 Third Quarter Earnings Conference Call on Thursday, October 29, 2009 2Dynatronics Appoints Douglas Sampson as Vice President of Production and Research & Development 2
... features of the Mastercycler ep Extremely ... blocks with SteadySlope technology Intuitive graphic ... device, a Mini-Satellite system, or a PC-controlled ... (Electronic Sample Protection) Optional motorized lid for ...
PTC-100 cycler with gold/silver block with Hot Bonnet heated lid, holds one 96-well V-plate or96x0.2ml tubes...
PxE thermal Cycler. 0.5ml block holds 48 0.5 ml tubes or 96 0.3 ml tubes. Adjustable height heated lid. Outstanding uniformity. Advanced control algorithms for reduced reaction times. User frien...
... Thermo Electron's most advanced personal gradient option ... use sophisticated onboard software and a large ... offer performance, accuracy and simplicity in thermal ... customer driven features built up on years ...
Medicine Products: