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Fit People Release More Fat-Burning Molecules During Exercise
Date:5/27/2010

heart disease, stroke and type 2 diabetes, to prolonging life, said Emmanuel Skordalakes, an assistant professor in the Gene Expression and Regulation Program at the Wistar Institute in Philadelphia.

Yet researchers are still trying to understand the biological reasons that explain why exercise is good. Studies such as this provide "emerging evidence that begins to explain some of the biological processes and pathways that are regulated during exercise and which have a beneficial effect for us," Skordalakes said.

Even so, far more research has to be done before the research could have a practical application for human performance or illness, Skordalakes said.

"We can't just make these metabolites and gobble them down," Skordalakes said. "It's not as simple as that. These are very complex pathways and that has to be done very carefully."

The study was published in the May 26 issue of Science Translational Medicine.

More information

The U.S. Centers for Disease Control and Prevention has more on the benefits of exercise.



SOURCES: Robert Gerszten, M.D., director, clinical and translational research, Massachusetts General Hospital Heart Center, Boston; Emmanuel Skordalakes, Ph.D, assistant professor, Gene Expression and Regulation Program, Wistar Institute, Philadelphia; May 26, 2010, Science Translational Medicine


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