Navigation Links
Fish oil and red yeast rice studied for lowering blood cholesterol

ROCHESTER, Minn. -- A great deal of scientific evidence shows that cholesterol-reducing medications known as statins can help prevent coronary artery disease. Although the safety of these medications has been well documented, as many as 40 percent of patients who receive a prescription for statins take the drug for less than one year. Doctors believe that several factors -- including cost, adverse effects, poor understanding of statin benefits and patients' reluctance to take prescription medications long term -- may explain why some patients stop taking these medicines. In the July issue of Mayo Clinic Proceedings, a group of researchers from Pennsylvania examine whether an alternative approach to treating high blood cholesterol may provide an effective treatment option for patients who are unable or unwilling to take statins.

Study design

Researchers followed 74 patients with high blood cholesterol who met standard criteria for using statin therapy. Patients were randomly assigned to either the alternative treatment group or the statin group and followed for three months.

The alternative treatment group participants received daily fish oil and red yeast rice supplements, and they were enrolled in a 12-week multidisciplinary lifestyle program that involved weekly 3.5-hour educational meetings led by a cardiologist, dietitian, exercise physiologist and several alternative or relaxation practitioners. Red yeast rice is the product of yeast grown on rice. A dietary staple in some Asian countries, it contains several compounds known to inhibit cholesterol production.

The statin group participants received 40 milligrams (mg) of Zocor (simvastatin) daily, as well as printed materials about diet and exercise recommendations. At the end of the three-month period, participants from both groups underwent blood cholesterol testing to determine the percentage change in LDL cholesterol.


The researchers noted that there was a reduction in LDL cholesterol levels in both groups. The alternative treatment group experienced a 42.4 percent reduction, and the statin group experienced a 39.6 percent reduction. Members of the alternative therapy group also had a substantial reduction in triglycerides, another form of fat found in the blood, and lost more weight.

"Our study was designed to test a comprehensive and holistic approach to lipid lowering," notes the study's lead author, David Becker, M.D., a Chestnut Hill Hospital and University of Pennsylvania Health System cardiologist. "These results are intriguing and show a potential benefit of an alternative, or naturopathic, approach to a common medical condition."

Dr. Becker acknowledges that a larger, multicenter trial with longer follow-up is necessary to determine long-term compliance with the alternative regimen, because previous studies involving diet and exercise have found a high rate of patients unable or unwilling to follow lifestyle recommendations.

"The excellent adherence in the alternative group was undoubtedly related to the intensive follow-up, education and support provided for this group," says Dr. Becker.


Contact: John Murphy
Mayo Clinic

Related medicine news :

1. New research on mutation in yeast can enhance understanding of human diseases
2. Chinese Red Yeast Rice May Prevent Heart Attack
3. Report raises C. diff concerns; yeast-based probiotic shown to help significantly reduce recurrence
4. Yeast gives rise to new concept: cell fuel is brains behind division
5. Penn researchers find potential in yeast for selecting Lou Gehrigs disease drugs
6. Common misdiagnosis: most women believe they have a yeast infection when they dont
7. Effects of healing touch therapy being studied
8. No difference in sleep of OSA patients studied in a hospital vs. a hotel-based sleep center
9. Eltrombopag studied in Idiopathic Thrombocytopenic Purpura
10. New treatment option studied for bladder cancer
11. Lowering Dietary Fat May Help Prevent Prostate Cancer
Post Your Comments:
(Date:10/13/2015)... ... October 13, 2015 , ... ... IBM software products, introduced a new company, RightSensor™ LLC, an Internet of Things ... capability. RightSensor™ provides a fully-managed approach for customers requiring sensor hardware for ...
(Date:10/13/2015)... ... October 13, 2015 , ... Dr. Poneh Ghasri, dentist in ... September 18, 2015. The research, which was conducted at the Dental Institute at King's ... show connections between stress during pregnancy and future dental health in the child. For ...
(Date:10/13/2015)... ... ... A child without a healthy mouth is much more likely to have an ... has joined with Global Dental Relief (GDR) to help bring dental care ... SmileCareClub will donate one clinic visit to a child in Kenya. , “When SmileCareClub ...
(Date:10/13/2015)... , ... October 13, 2015 , ... ... solutions, announced today their Title Sponsorship of Synergy 2015. The annual WennSoft KEY2ACT ... at Green Valley Ranch and will unite customers, partners, WennSoft team members and ...
(Date:10/13/2015)... , ... October 13, 2015 , ... ... McHenry County, Illinois with more than 59,000 emergency department visits per year, today ... (EDIS) from T-System, to help improve clinical, operational and financial outcomes. ...
Breaking Medicine News(10 mins):
(Date:10/13/2015)... 13, 2015 TriGuard™ Cerebral Protection ... findings from the multicenter Neuro-TAVR study with the clinical ... San Francisco this week. --> ... will be sharing additional findings from the multicenter Neuro-TAVR ... (TCT) meeting in San Francisco ...
(Date:10/13/2015)... According to the 2015 National ... Cardinal Health , achieving both higher patient ... revenue streams are vital to the future success ... Digest affirms that independent community pharmacies are ... inner city and rural areas," said NCPA CEO ...
(Date:10/13/2015)... WASHINGTON , Oct. 13, 2015  Measurement ... quality improvement and balancing financial incentives, but gaps ... improve patient care and health systems. A new, ... Journal of Managed Care explores measurement ... improve measure sets. --> ...
Breaking Medicine Technology: