Navigation Links
Fish Oil May Help Prevent Alzheimer's
Date:12/28/2007

Omega-3 fatty acid boosts protein that destroys brain plaques, study finds

FRIDAY, Dec. 28 (HealthDay News) -- The omega-3 fatty acids found in fish oil might play an important role in preventing Alzheimer's disease, according to a research team at the University of California, Los Angeles (UCLA).

Publishing in the Dec. 26 issue of the Journal of Neuroscience, the scientists demonstrated that the omega-3 fatty acid docosahexaenoic acid (DHA) increases the production of LR11, a protein that is found at reduced levels in Alzheimer's patients. LR11 is known to destroy the protein that forms the plaques associated with the disease, the researchers explained.

The plaques are actually a buildup of a protein called beta amyloid, which is thought to be toxic to brain cells. Higher levels of LR11 prevent the manufacturing of the toxic proteins, which is why researchers believe the low levels found in the brains of Alzheimer's patients may be a contributing factor to the disease.

Alzheimer's is a debilitating neurodegenerative disease that causes memory loss, dementia, personality change and ultimately death. The Alzheimer's Association estimates that 5.1 million Americans are currently afflicted with the disease. The association predicts that may increase to between 11 million and 16 million people by 2050.

The researchers tested the effects of DHA by adding it directly to human and animal neurons grown in the laboratory.

"We found that even low doses of DHA increased the levels of LR11 in rat neurons, while dietary DHA increased LR11 in brains of rats or older mice that had been genetically altered to develop Alzheimer's disease," lead researcher Greg Cole, associate director of UCLA's Alzheimer Disease Research Center, said in a prepared statement.

Fatty acids such as DHA are considered essential fatty acids, because the body cannot make them from other sources and must obtain them through diet. Years of research have shown that DHA is the most abundant essential fatty acid in the brain, Cole said, and that it is critical to fetal and infant brain development. Studies have also linked low levels of DHA in the brain to cognitive impairment and have shown that lower levels may increase oxidative stress in the brains of Alzheimer's patients.

The research team acknowledged that their work does not identify a dosage of DHA that people could take to prevent Alzheimer's, but they recommend eating more fatty fish or taking a supplement. They did not recommend taking DHA to try to slow the progression of Alzheimer's.

More information

To learn more about Alzheimer's disease, visit the National Institute on Aging.



-- Madeline Vann



SOURCE: University of California, Los Angeles, news release, Dec. 25, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Breast cancer prevention practices vary across Canada
2. Blood-flow detector software show promise in preventing brain damage
3. Red wine compound shown to prevent prostate cancer
4. School-based overweight prevention program may cut risk of eating disorders among girls
5. Avocados may help prevent oral cancer, OSU study shows
6. What is Being Done to Prevent Misdiagnosis?
7. MultiVu Video Feed: PUBLIC HEALTH EXPERTS CONVENE TO DISCUSS THE TREATMENT AND PREVENTION OF RABIES
8. Preventing variceal bleeding
9. Jump in Youth Suicide Prompts National Childrens Charity KidsPeace to Issue Tips on Prevention, Warning Signs
10. ABQAURP Announces Certificate Course in Medical Error Prevention
11. Scientists, physicians present latest findings in personalized cancer treatment and prevention
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/20/2017)... ... February 20, 2017 , ... ... full range of emergency dental care at his office, Antoine Dental Center. Emergency ... experience dental emergencies, they are at risk for serious complications and often experience ...
(Date:2/19/2017)... ... February 19, 2017 , ... The Citadel’s new Swain Department ... being led by Amelia Joseph, Ph.D. Joseph was engaged by the college as a ... department in early 2016. After a nation-wide search, she was selected to head the ...
(Date:2/18/2017)... ... February 17, 2017 , ... ... Devicemakers , Sponsored by Axendia, **FDAnews Free Webinar**, March 1, 2017 — ... looking to reduce their regulatory burden? Pay dividends in enhanced and predictable ...
(Date:2/18/2017)... ... February 18, 2017 , ... ProParagraph Fashion ... Film Studios ’ ProParagraph Fashion Volume 2 for all multi-line FCPX project needs. ... Users can pick and choose from hand-crafted trend-setting designs with smooth animations that ...
(Date:2/17/2017)... ... February 17, 2017 , ... Wells Pharmacy ... electronic prescribing of controlled and non-controlled substances plus the ability to manage orders ... the United States now accept electronic prescriptions, according to the Office of the ...
Breaking Medicine News(10 mins):
(Date:2/20/2017)... New York , February 20, 2017 ... regularized absorption of calcium and phosphorous minerals in one,s ... of vitamin D ingredients in maintaining a healthy composition ... medicines containing vitamin D ingredients is growing in the ... advantage of consuming vitamin D ingredients for treatment of ...
(Date:2/19/2017)... 19, 2017  nThrive™, an independent Patient-to-Payment? solutions ... thought leadership at the 2017 HIMSS Conference. The ... award from KLAS. nThrive will host ... how market trends shape the holistic, integrated revenue ... comprehensive Patient Access solution. The panel will reveal ...
(Date:2/18/2017)... PORT WASHINGTON, N.Y. , Feb. 17, 2017 ... law firm dedicated to protecting the rights of ... device problems have prompted regulators to call for ... events in 1990. Safety concerns involving ... and Drug Administration (FDA) to investigate how hospitals ...
Breaking Medicine Technology: