Navigation Links
First successful use of expanded umbilical-cord blood units to treat leukemia
Date:1/17/2010

SEATTLE Scientists at Fred Hutchinson Cancer Research Center have cleared a major technical hurdle to making umbilical-cord-blood transplants a more widely-used method for treating leukemia and other blood cancers.

In a study published in the Jan.17 edition of Nature Medicine, Colleen Delaney, M.D., and colleagues describe the first use of a method to vastly expand the number of stem/progenitor cells from a unit of cord blood in the laboratory that were then infused into patients resulting in successful and rapid engraftment.

The relatively small number of stem cells in cord blood units (about one-10th the number a patient receives from a conventional transplant) has been a reason that cord blood transplants take much longer to engraft than standard stem cell transplants from donors. The longer the engraftment takes, the higher the risk is that immunocompromised patients will acquire life-threatening infections because they have essentially no white blood cells to fight them.

Despite the numbers disadvantage, cord blood is a promising source of stem cells to replace diseased blood and immune systems in stem cell transplantation because the donated cells don't need to be perfectly matched to the patient. The lack of a suitable match is why about 30 percent of patients overall who need a stem cell transplant to treat cancers such as leukemia can't find suitable donors. Among racial-minority patients the number who cannot find suitable donors is about 95 percent.

The use of expanded cord blood cells could decrease the risk of early death, which is higher in patients receiving a cord-blood transplant without expanded cells. Further clinical trials and technological improvements are needed to verify the efficacy of cord blood transplants that use expanded cells, the authors said.

"The real ground-breaking aspect of this research is that we have shown that you can manipulate stem/progenitor cells in the lab with the goal of increasi
'/>"/>

Contact: Dean Forbes
dforbes@fhcrc.org
206-667-2896
Fred Hutchinson Cancer Research Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. First biomarker discovered that predicts prostate cancer outcome
2. FDA Approves First Anti-Psychotic for Kids
3. Single-incision belly-button surgery to remove kidney performed first at UT Southwestern
4. First study examines newly-licensed RN work attitudes and intentions
5. Glades General Hospital First in Palm Beach County to Provide On-Site Electronic Birth Registration
6. UHW Announces: Antelope Valley Hospital Caregivers and Board Vote to Ratify First Union Contract With SEIU UHW-West
7. Father and Daughter From Tanzania Receive Their First Medical Examination in Newport Beach
8. High and mighty: first common height gene identified by researchers behind obesity gene finding
9. APA Comments on FDAs First Approval of Medication to Treat Pediatric Schizophrenia and Bipolar Disorder
10. TriWest Creates First-of-its-Kind Partnership to Offer Military Leaders With Grief Support Program
11. Watson Receives First FDA Approval for Manufacturing Product at Its Goa, India Facility
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... The family of a Vermont man ... Xarelto lawsuit ( http://www.xareltolawsuitcenter.com/ ) alleging his death ... reports. According to the complaint, which was filed in ... July 25th, the decedent had been taking Xarelto for ... bleed that ultimately led to his death on August ...
(Date:7/30/2014)... (PRWEB) July 30, 2014 Hamilton ... opening of its new Carmel office on July 30th. ... will finally be moving to the state-of-the-art suite, located ... and innovative space will allow for one-on-one patient comfort, ... surgery experience. , Dr. Hamilton’s new office-suite will ...
(Date:7/30/2014)... 2014 DRE Medical — a leading ... launch of its Medical Trade Shows & Conventions ... professionals and equipment vendors. , The calendar is a ... the United States and around the world. Hundreds of ... number is always growing. , Information listed on each ...
(Date:7/30/2014)... The Technology Association of Georgia in ... (B&TA), today issued its final call for applications and ... companies have until August 29th 2014 to be considered ... selected by the Excalibur Judging Committee. Companies selected as ... judges for interviewing process. , The TAG Excalibur ...
(Date:7/30/2014)... (PRWEB) July 30, 2014 LTC Consumer, an ... long term care insurance, features an Instant Quote tool on ... and co-founder of LTC Consumer. Quotes are free and unlimited. ... click in only seven areas – including age, gender, and ... screen within seconds (you don’t need to enter any contact ...
Breaking Medicine News(10 mins):Health News:Xarelto Lawsuit Alleges Man’s Death from Uncontrollable Brain Bleeding Was Caused by Xarelto, Bernstein Liebhard LLP Reports 2Health News:Xarelto Lawsuit Alleges Man’s Death from Uncontrollable Brain Bleeding Was Caused by Xarelto, Bernstein Liebhard LLP Reports 3Health News:Hamilton Facial Plastic Surgery Opens New Carmel Office 2Health News:DRE Launches Online Interactive Medical Trade Show Calendar 2Health News:Last Call for TAG 2014 Excalibur Awards Nominations and Applications 2Health News:Last Call for TAG 2014 Excalibur Awards Nominations and Applications 3Health News:LTC Consumer Launches Online Tool for Getting Instant Long Term Care Insurance Estimates 2
... acclaimed as the "gold-standard" amongst researchers for scientific studies. ... on the other, has also questioned the worth of ... complementary and alternative medicine (CAM) practices. Majority of CAM ... cure. , ,The question arises as to whether ...
... Diabetes is the leading cause of end-stage kidney disease ... or a kidney transplant for survival. // ,A ... and the University of Heidelberg has proven that a ... kidney failure or "end-stage renal disease." ,The ...
... are facing one of the worst gastroenteritis epidemics that ... with patients coming// in droves for relief. The infection ... for a few days but seldom endangers life. ... Montreal area have reported the viral outbreak. Dr. Joseph ...
... have been created from blue green algae by scientists with ... on properties and actions of enzymes is also taken into ... possible to produce enough of the promising drugs for use ... the cover of the January issue of the journal ACS ...
... recent studies have shown that the chance of developing it ... the chances of surviving it, also depend on the same ... 50,000 pounds behind a study to be carried out by ... cancer survivors aged above fifty and with a BMI (Body ...
... detect infection of drug resistant forms of HIV even when ... the Duke University Medical Center. ,This new test ... in small amounts contrary to other tests that detect drug-resistant ... bloodstream. ,This new test is expected to be ...
Cached Medicine News:Health News:Is Evidence-based Medicine Enough to Support Additional Research in Alternative Medicine? 2Health News:A Gene Associated With Severe Kidney Failure in Diabetes Found 2Health News:Anti Cancer Drug from Blue Green Algae 2
(Date:7/30/2014)... SCHOFIELD, Wis. , July 30, 2014 /PRNewswire/ ... researcher, developer, and marketer of over-the-counter (OTC) medicinal ... is rebranding the LipiGesic ® M name along with ... will be replaced with the trademarked name MigraPure ... and color palette of PuraMed,s homeopathic, natural migraine ...
(Date:7/30/2014)... 30, 2014  El Camino Hospital, a leader in ... utilizing the Leaf Patient Monitoring system to help prevent ... of patients susceptible to bed sores. The ... study of the system, which showed dramatic improvement in ... regularly is the one of the most effect ways ...
(Date:7/30/2014)... -- InnoPharma, Inc. today announced the first generic launch of ... injection), in Canada.  Olanzapine is indicated for the rapid ... schizophrenia or bipolar I mania. As the ... into an agreement with Sandoz Canada Inc., pursuant to ... market and distribute Olanzapine Injection in Canada ...
Breaking Medicine Technology:PuraMed BioScience Rebrands its Natural Migraine Relief Medication, LipiGesic M 2PuraMed BioScience Rebrands its Natural Migraine Relief Medication, LipiGesic M 3El Camino Hospital Utilizes Cutting-Edge Leaf Patient Monitor System to Help Reduce Risk of Pressure Ulcers 2El Camino Hospital Utilizes Cutting-Edge Leaf Patient Monitor System to Help Reduce Risk of Pressure Ulcers 3InnoPharma Announces Launch of Olanzapine for Injection, 10mg/vial in Canada 2
... ... ... ... ...
... ... ... ... ...
Cached Medicine Technology:Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 2Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 3Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 4Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 5Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 6Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 7Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 8Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 9Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 10Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 11Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 12Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 13Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 14Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 15Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 16Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 17Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 18Par Pharmaceutical Companies Reports Adjusted EPS of $0.65 for Fourth Quarter 2009 19Zargis StethAssist & Zargis Cardioscan Cleared for Sale in Australia 2Zargis StethAssist & Zargis Cardioscan Cleared for Sale in Australia 3Zargis StethAssist & Zargis Cardioscan Cleared for Sale in Australia 4Zargis StethAssist & Zargis Cardioscan Cleared for Sale in Australia 5Zargis StethAssist & Zargis Cardioscan Cleared for Sale in Australia 6
... Small Bone Power System combines precision ... under the most exacting conditions. The ... small bone osteotomies and oral/maxillofacial procedures ... Length Available), Oscillating Saw (Extended Length ...
... The Hall® Surgical E9000® System ... offers multiple electric handpieces specifically designed ... and Oral/Maxillofacial Surgery. The E9000 System ... console and 3 specialized handpieces designed ...
... USA™ Battery Tester is ... efficiently determine if your ... Extended Run, Stryker® 2115, ... Packs contain adequate charge ...
... offers a comprehensive line of high speed ... piece construction method that minimizes breakage. Using ... polished to create the sharpest edge possible, ... procedure., ,Our high speed cutters come ...
Medicine Products: