Navigation Links
First pediatric autism study conducted entirely online
Date:6/30/2014

UC San Francisco researchers have completed the first Internet-based clinical trial for children with autism, establishing it as a viable and cost effective method of conducting high-quality and rapid clinical trials in this population.

In their study, published in the June 2014 issue of the Journal of the American Academy of Child and Adolescent Psychiatry, the researchers looked at whether an Internet-based trial was a feasible way to evaluate whether omega-3 fatty acids helped reduce hyperactivity in children with autism. The authors found that not only was it a valuable platform for conducting the randomized clinical trial, but that it was both cost and time effective, as well.

"Recruitment for clinical trials in children with autism is one of the biggest challenges we face in studying potential treatments, and we found that process to be accelerated and streamlined by using existing online communities for enrollment," said lead author Stephen Bent, associate professor of medicine at UCSF. "This trial can serve as a model for how to efficiently test potential treatments through the growing power of online communities."

Using the Interactive Autism Network's (IAN) robust online community of parents, the researchers enrolled 57 children from 28 states into the randomized trial.

The enrolled children were randomly assigned to either receive 1.3 grams of omega-3 fatty acids or an identical placebo daily for six weeks. Once a week the participants' parents received an email asking them to complete outcome measures on how their child was doing and report on the child's level of hyperactivity. The children's teachers reported on changes in hyperactivity as well. The parent and teacher responses were submitted to a database, allowing the researchers to access the data immediately.

Because the IAN requires that parents complete a short questionnaire and verify that their child has been professionally diagnosed in order to participate in the online network, the researchers were able to confirm the participants met the diagnostic criteria for autism without a clinic visit.

While the researchers found that the omega-3 fatty acids did not lead to a statistically significant reduction in hyperactivity, they concluded the online trial was a promising technique for evaluating treatments for autism.

"The entire study was completed in slightly more than three months from the start of enrollment, and demonstrates there are many advantages including low cost, rapid enrollment, high completion rate, convenience for participating families, and the ability to participate from virtually any location," said Bent. "We had 100 percent completion of all outcome measures from parents and teachers, indicating that there is an ease to this method of testing that engages parents at a higher rate than traditional trials."


'/>"/>

Contact: Juliana Bunim
juliana.bunim@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert

Related medicine news :

1. First comprehensive pediatric concussion guidelines, available now
2. The first demonstration of a self-powered cardiac pacemaker
3. Blood sugar improves with first gastrointestinal microbiome modulator, NM504
4. New study is first to identify, clarify MERS-related abnormality distribution on CT
5. First first patient enrolled in PROSPECT II clinical trial
6. First articles published in new Journal of Medical Imaging
7. First clinical diabetes registry to provide seamless view of patients across specialties
8. Five-question clinical tool the first to help screen risk of violence in military veterans
9. First survey of ACOs reveals surprising level of physician leadership
10. First-of-its-kind study: Swimmers gain an advantage when they recover with chocolate milk
11. NIH Pain Consortiums first pain care curriculum improves clinical skills
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/17/2019)... ... August 17, 2019 , ... ... America’s Fastest-Growing Private Companies—the Inc. 5000 , For the 2nd Year In a ... Revenue Growth of 192% Percent , Inc. magazine today revealed that YellowTelescope LLC ...
(Date:8/16/2019)... ... August 16, 2019 , ... The clinical trial supply chain landscape is constantly ... , Join Just In Time Manufacturing Solutions Manager at Almac Clinical Services , ... 11am EDT (4pm BST/UK) on a journey through time as it relates to clinical ...
(Date:8/16/2019)... ... August 16, 2019 , ... ... market, has joined the esteemed Haute Beauty Network. , The Haute Beauty Network, ... to present Dr. Arnaoutakis as a hair restoration expert and our newest addition ...
(Date:8/15/2019)... ... 15, 2019 , ... With many students either starting college for the first time, and returning ... to the CDC , “there are about 20 million new cases of STDs each ... ages of 15 and 24. Young people are at greater risk of getting an STD.” ...
(Date:8/14/2019)... ... August 14, 2019 , ... Teguar Corporation has claimed the ... This list has long-been established as a mark of success for some of Americas ... Oracle. Teguar made the list in 2015, 2016 and 2017. This year, Teguar secured ...
Breaking Medicine News(10 mins):
(Date:8/21/2019)... ... August 21, 2019 , ... ... Healthcare’s Construction and Design Survey, has added Operational Readiness to its integrated ... overlay to clients’ capital projects, working with the clinical and operational leadership ...
(Date:8/21/2019)... ... August 21, 2019 , ... ... Module for its voice-activated notification and communication solution—with new features to help ... discharged patients. , Leveraging the innovative Amazon Alexa voice assistance technology, ...
(Date:8/19/2019)... ... August 19, 2019 , ... ... hosting their 2nd Annual National Sports Summit, August 25-26 at the Hyatt Place ... clinical leaders from all major professional sports programs to discuss progress made over ...
Breaking Medicine Technology: