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First guidelines for brain amyloid imaging in Alzheimer's released
Date:1/27/2013

ric H. Fahey, D.Sc., SNMMI president. "Neurology and dementia experts should order the test only when appropriately indicated, and nuclear medicine and molecular imaging professionals must ensure they have been adequately trained to interpret the results of the scan. Working together, we hope that the information garnered from amyloid PET imaging will aid in diagnosis and play a pivotal role in the development of new treatments for Alzheimer's."

The taskforce acknowledged that the healthcare provider makes the ultimate judgment regarding the care of each patient. The AIT sought to assist this process and identified the following general sequence of events for the use of amyloid PET according to the new criteria:

  1. Evaluation by a dementia expert to assess the need for diagnostic testing, possibly to include amyloid PET if the AUC are met.
  2. Referral to a qualified provider of amyloid PET services.
  3. Performance, interpretation and reporting of the amyloid PET scan according to established standards.
  4. Incorporation of the PET result into the clinical assessment process.
  5. Disclosure of the PET result by the clinician to the patient and caregivers, along with discussion of the result and its management consequences.

Although identifying potential benefits, the AIT concluded that amyloid PET results will not constitute and is not equivalent to a clinical diagnosis of Alzheimer's disease dementia. They said that imaging is only one tool among many that clinicians should use judiciously to manage patients, and that amyloid PET imaging does not substitute for a careful history and examination.

"Because both dementia care and amyloid PET technology are in active development, these new appropriate use criteria will require periodic reassessment and updating," Carrillo said.

PET Amyloid Imaging in Alzheimer's An Overview

PET uses radiopharmaceuticals (radioactive drugs) to produce three-dimension
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Contact: Susan Martonik
smartonik@snmmi.org
703-652-6773
Society of Nuclear Medicine
Source:Eurekalert

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