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First generation antipsychotic drugs as effective as newer ones in some children
Date:9/14/2008

e point when we went to see Dr. Sikich, when Brandon was 14, I was getting phone calls from the school because he was making threats against teachers, said Brandons mother, Darlene Wilson. This coincided with violent threats against his parents and, Brandon said, at one point in time I thought I was seeing angels with halos and wings, like in the Bible.

A psychiatrist Brandon had been seeing was not helpful, Wilson said, so a pediatrician referred them to Sikich.

Late diagnosis is a common problem with many children who develop early onset schizophrenia or schizoaffective disorder, and the diseases usually develop more severely when they begin in childhood, Sikich said.

Brandon is now doing well on an even newer drug, ziprasidone. But in the TEOSS trial only half of all of the participants responded to any medication.

Medications make a vast difference in peoples lives, but we need better treatment options, Sikich said. The trial will next compare outcomes after a one-year course of treatment.

Brandon and his family appreciate first-hand the challenges and advances.

Its working well for him and we need to enjoy the good times, because its not always good times, Wilson said. We just have to enjoy what we have right now.


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Contact: Clinton Colmenares
ccolmena@unch.unc.edu
919-966-8757
University of North Carolina School of Medicine
Source:Eurekalert

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