Navigation Links
First evidence from humans on how alcohol may boost risk of cancer
Date:8/22/2012

PHILADELPHIA, Aug. 22, 2012 Almost 30 years after discovery of a link between alcohol consumption and certain forms of cancer, scientists are reporting the first evidence from research on people explaining how the popular beverage may be carcinogenic. The results, which have special implications for hundreds of millions of people of Asian descent, were reported here today at the 244th National Meeting & Exposition of the American Chemical Society.

Silvia Balbo, Ph.D., who led the study, explained that the human body breaks down, or metabolizes, the alcohol in beer, wine and hard liquor. One of the substances formed in that breakdown is acetaldehyde, a substance with a chemical backbone that resembles formaldehyde. Formaldehyde is a known human carcinogen. Scientists also have known from laboratory experiments that acetaldehyde can cause DNA damage, trigger chromosomal abnormalities in cell cultures and act as an animal carcinogen.

"We now have the first evidence from living human volunteers that acetaldehyde formed after alcohol consumption damages DNA dramatically," Balbo said. She is a research associate in the laboratory of Stephen Hecht, Ph.D., a noted authority on cancer prevention at the University of Minnesota. "Acetaldehyde attaches to DNA in humans ― to the genetic material that makes up genes - in a way that results in the formation of a 'DNA adduct.' It's acetaldehyde that latches onto DNA and interferes with DNA activity in a way linked to an increased risk of cancer."

Balbo pointed out that people have a highly effective natural repair mechanism for correcting the damage from DNA adducts. Most people thus are unlikely to develop cancer from social drinking, although alcohol is associated with a risk of other health problems and accidents. In addition, most people have an enzyme called alcohol dehydrogenase, which quickly converts acetaldehyde to acetate, a relatively harmless substance.

However
'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
215-418-2056 (Philadelphia Press Center, Aug. 17-23)
202-872-6042

Michael Woods
m_woods@acs.org
215-418-2056 (Philadelphia Press Center, Aug. 17-23)
202-872-6293
American Chemical Society


Source:Eurekalert

Page: 1 2

Related medicine news :

1. First identification of a strong oral carcinogen in smokeless tobacco
2. IHME professor named first health measurement winner of prestigious innovation award
3. FDA Gives Nod to First Drug for Diabetic Eye Disease
4. Mayo Clinic completes first genome-wide analysis of peripheral T-cell lymphomas
5. Women and Children First? Not So, Says Study
6. WPI to host international workshop focused on technology solutions for first responders
7. First Huntingtons disease center established in Washington, D.C., area
8. Study Gives First Evidence That Adult Human Lungs Can Regrow
9. Hookah smoking increasingly common among first-year college women
10. Sohn Conference and Damon Runyon Cancer Research Foundations name first pediatric research fellows
11. Scientists first to see trafficking of immune cells in beating heart
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/2/2015)... 2015 Gummy smile reduction expert, ... reshaping can involve one or several procedures to reduce the ... tissue for a more even gum line. Dr. Farnoosh is ... that can permanently lighten discolored or naturally dark gums. ... involves a personalized treatment plan to address a patient’s specific ...
(Date:3/2/2015)... Burns Engineering's Lab-to-Lab Calibration Service offers ... Platinum Resistance Thermometers (SSPRTs) and industrial Resistance Temperature ... . . . guaranteed. Their metrology ... 200706-0), ISO 9001 and 17025 Certified and provides ... to 500°C, both ITS-90 and Callendar-van Dusen calibrations ...
(Date:3/2/2015)... Over the last five years the ultrasound ... to expand their geographic presence and achieve economies of ... $6.2 billion by 2019 at CAGR of 5.1% from ... and Canada and a major part of Europe are ... as Asia-Pacific including China and India, Latin America and ...
(Date:3/2/2015)... This year, the National Multiple Sclerosis Society’s annual awareness ... people across the country to unite, raise awareness, ... their best lives. MS Awareness Week is a special week ... the Society’s vision of a world free of MS. ... the central nervous system, interrupts the flow of information within ...
(Date:3/2/2015)... 02, 2015 Atlantic Information Services, Inc. ... AIS’s Directory of Health Plans: 2015 , the all-new ... the U.S. health plan market, with enrollment data and ... States. , Available as a printed book containing ... trends in quick-view tables and charts, as well as ...
Breaking Medicine News(10 mins):Health News:Gummy Smile Expert, Dr. Alex Farnoosh, is Now Offering Gum Reshaping Procedures 2Health News:Burns Engineering Announces Quick-Turn Temperature Calibrations 2Health News:Therapeutic Ultrasound Devices Market worth $6.2 Billion by 2019 - New Research Report by MarketsandMarkets 2Health News:Therapeutic Ultrasound Devices Market worth $6.2 Billion by 2019 - New Research Report by MarketsandMarkets 3Health News:Every Connection Counts During MS Awareness Week 2Health News:Every Connection Counts During MS Awareness Week 3Health News:Every Connection Counts During MS Awareness Week 4Health News:Now Available from AIS: 12th Edition of Annual Book Containing Health Plan Enrollment Data, Contact Information 2
... 21 Secretary of Veterans,Affairs Dr. James B. Peake ... panels that will make recommendations on ways the Department,of ... prevention,suicide research and suicide education., "There is nothing ... one of,the great men or women who have served ...
... 1 Day ASV Single Vision Lens Now Available Through Licensed Eye Care ... ... Inc. (OTC,Bulletin Board: UVICF; TSX Venture Exchange: UVI), which develops,licenses, manufactures, distributes ... C-VUE(R) 1 Day ASV, which is the,first aspheric, daily disposable contact lens ...
... Leading Pennsylvania Health Insurer Reduce ... DST Health Solutions,today announced an extension of ... health insurer serving nearly 3.4 million,members, for business ... center in Harrisburg, Pa. will,continue to provide business ...
... the Most Promising ... Driving the Future of Technology, SUNNYVALE, Calif., May ... technology in enterprise mobility,today announced that it has won ... most innovative private technology companies based in North,America., ...
... young flight attendant,complains of swelling and tightness in ... her from exercising. Will the ultrasound results indicate,deep ... symptomatology and the frequent presence of comorbidities,make it ... primary care,practice. The Journal of Family Practice has ...
... Thoracic Societys 2008 International Conference in Toronto on Wednesday, May ... young adults. One links low levels of a protein called ... in young women. A second finds that high levels of ... , The data from both studies comes from the ...
Cached Medicine News:Health News:VA Secretary Appoints Panel of National Suicide Experts 2Health News:Unilens Launches Aspheric C-VUE(R) Daily Disposable Lens 2Health News:DST Health Solutions and Independence Blue Cross Extend Business Process Outsourcing Agreement 2Health News:DST Health Solutions and Independence Blue Cross Extend Business Process Outsourcing Agreement 3Health News:Agito Networks Wins Red Herring North America 100 Award Out of More Than 800 Companies 2Health News:Agito Networks Wins Red Herring North America 100 Award Out of More Than 800 Companies 3Health News:CME Publication Gives Clinicians a Leg Up in Treating Disorders of the Lower Extremities 2Health News:Studies provide insights into lung disease and lung function in young adults 2Health News:Studies provide insights into lung disease and lung function in young adults 3
(Date:3/2/2015)... 2, 2015   Emerson Ecologics, LLC ... supplements, prescription products and natural health and ... with Anabolic Laboratories, a leading manufacturer of ... new partnership will allow Anabolic Laboratories to ... practitioner segments and provide customers with added ...
(Date:3/2/2015)... BUENA, N.J., March 2, 2015  IGI Laboratories, Inc. (NYSE ... announced its financial results for the fourth quarter and year ... to Date 2014 Highlights , Total revenues of ... of 104% over the same quarter in 2013 , ... 31, 2014, an increase of 85% over the same period ...
(Date:3/2/2015)... March 2, 2015 Halozyme Therapeutics, Inc. (NASDAQ: ... and full year ended December 31, 2014. Financial highlights for ... net loss of $5.3 million, or $0.04 per share. This ... of $22.0 million, or $0.19 per share, for the fourth ... include revenues of $75.3 million and a net loss of ...
Breaking Medicine Technology:Anabolic Laboratories Selects Emerson Ecologics As Distribution Partner 2Anabolic Laboratories Selects Emerson Ecologics As Distribution Partner 3IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 2IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 3IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 4IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 5IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 6IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 7IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 8IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 9IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 10IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 11IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 12Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 2Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 3Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 4Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 5Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 6Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 7Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 8Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 9
... Mass., Aug. 26 Sermo ... physicians, today announced a free Sermo Report titled, " ... covers physician opinions about the introduction of an investigational ... to the results, 46% of physicians feel that ticagrelor ...
... Cardioxyl Pharmaceuticals, Inc. , a clinical-stage pharmaceutical ... disease, today announced that it has initiated a dose-defining ... for the treatment of patients with acute decompensated heart ... at the time of discharge from U.S. hospitals and ...
Cached Medicine Technology:Sermo Report Indicates that Ticagrelor is Likely to Affect the Standard of Care for ACS Patients 2Cardioxyl Pharmaceuticals Initiates Dose-Defining Phase IIa Study of Its Lead Candidate, CXL-1020, in Heart Failure Patients 2Cardioxyl Pharmaceuticals Initiates Dose-Defining Phase IIa Study of Its Lead Candidate, CXL-1020, in Heart Failure Patients 3Cardioxyl Pharmaceuticals Initiates Dose-Defining Phase IIa Study of Its Lead Candidate, CXL-1020, in Heart Failure Patients 4
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: