Navigation Links
First do no harm? UH prof taking opposite approach to treat asthma
Date:4/9/2008

HOUSTON, April 9, 2008 One month of tough breathing may help asthma sufferers breathe easier in the long run, according to research from one University of Houston professor.

In a move that challenges one of the most basic tenets of the Hippocratic Oath first do no harm Richard Bond, associate professor of pharmacology at UH, is relying on a long-standing medical taboo to treat asthma. Although counterintuitive, Bonds studies are reminiscent of hair-of-the-dog folk wisdom to treat like with like, in this case using beta blockers (or antagonists) instead of stimulants (or agonists) in asthmatics.

Coining the term paradoxical pharmacology treating patients with medicine that initially worsens their symptoms before eventually improving their overall health Bond first applied this hypothesis in studies with mice and then moved on to two clinical trials with humans. Currently in the second clinical trial, the part of this research analyzing mice was recently published in the American Journal of Respiratory Cell and Molecular Biology, which cited the relevance of Bonds work as possibly leading to a paradigm shift in the treatment of asthma. The results of the first human trial were also recently published in Pulmonary Pharmacology and Therapeutics.

Acute asthma attacks have traditionally been treated with inhaler-type stimulant drugs that open constricted airways. Giving beta blockers to asthmatics has long been thought to be contraindicated, because their acute use may cause increased airway resistance. While the use of beta-stimulants is known to provide temporary relief, their effectiveness declines over time.

Bonds tests initially done on asthmatic mice and later replicated in his first clinical trial with humans showed that while beta blockers initially made breathing problems worse, their continued use resulted in improved respiratory function after a 28-day period. These longer-term effects demonstrate th
'/>"/>

Contact: Lisa Merkl
lkmerkl@uh.edu
713-743-8192
University of Houston
Source:Eurekalert  

0

GOOD

Page: 1 2 3 4

Related medicine news :

1. Ventas Announces 2008 First Quarter Earnings Release Date and Conference Call
2. Study: Treating post-traumatic stress first helps children overcome grief
3. Advancing Interoperability - Nonin(R) Medical Unveils Worlds First Bluetooth(R)-Enabled, Wireless Fingertip Pulse Oximeter
4. Albemarle Corporations First Quarter 2008 Earnings Conference Call To Be Held April 22, 2008 at 8:00am ET
5. VNUS Medical Technologies to Report First-Quarter 2008 Results and Webcast Teleconference on April 21
6. Albemarle Corporations First Quarter 2008 Earnings Conference Call To Be Held April 22, 2008 at 9:00am ET
7. GetWellNetwork Kicks Off GetConnected2008, First Annual Users Conference
8. Barr Will Host An Earnings Conference Call on May 8, 2008 to Discuss the Results for the First Quarter of Calendar 2008
9. Stiefel Laboratories Appoints First Chief Scientific Officer
10. Quest Diagnostics to Release First Quarter 2008 Financial Results and Conduct Quarterly Investor Conference Call
11. Exponent to Report First Quarter Fiscal 2008 Results
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
First do no harm? UH prof taking opposite approach to treat asthma
(Date:5/21/2013)... Limited mobility affects people in ways that the ... difficult to walk around, but everyday tasks like getting up ... of medical products made to assist those who need a ... seat. , Raised toilet seats keep users further ... or sit down. They come in a variety of sizes ...
(Date:5/20/2013)... Heritage Woods of Gurnee , ... Illinois, is hosting Breakfast and Bingo at 8:30 a.m. ... located at 3775 Grand Ave. in Gurnee, Illinois, serves ... who need some help to maintain their independence. , ... of bingo," says Tammy Temaner-Rosas, Director of Marketing for ...
(Date:5/20/2013)... When a shopper decides to buy a mattress ... process. Much of the stress and concern people express with ... to expect. Best Mattress Online, a blog about mattress ... their purchase proves smooth. , In the article, titled “ ... readers find helpful tips divided into two sections, questions to ...
(Date:5/20/2013)... Fastcare Miami Beach clinic advises patients to treat ... as if not treated, it may involve the ureter and ... urinary tract infection in itself is not life threatening, if ... pyelonephritis. Women seem to have many more urinary tract infections ... as women after the age of fifty. , As ...
(Date:5/20/2013)... 2013 Eben Pagan's Accelerate ... public creating a frenzy among business owners and ... business training. WealthSpringMarketing.com's Tiffany Hendricks has published a ... exclusive bonus. , "Eben Pagan is a world ... to individuals serious about success," reports Hendricks. "Prior ...
Breaking Medicine News(10 mins):Health News:JustHomeMedical.com Launches Raised Toilet Seats Category 2Health News:Heritage Woods of Gurnee Affordable Assisted Living Community to Host Breakfast and Bingo 2Health News:See What to Expect When You Buy a Mattress Online With Latest Guide From Best Mattress Online 2Health News:Fastcare Advises on How to Prevent a UTI 2Health News:Eben Pagan's Accelerate: Review and Bonus Released By WealthSpringMarketing.com 2
... ... 2009CLEVE to get their $54 marrow cheek-swab kit at no cost. , ... (Vocus) June 15, 2009 -- Two-year-old Eve is one of ... but so far her family has been unable to find one. Thanks to the Gift ...
... NATICK, Mass., June 15 Boston Scientific Corporation (NYSE: ... nine studies involving the Company,s Urology/Gynecology products will be ... Urogynecological Association (IUGA). Presentations will feature Boston Scientific,s ... to treat pelvic floor prolapse and stress urinary incontinence ...
... Unique Intelligent Order Routing allows hospital pharmacies to design ... levels , , ROSEMONT, Ill., June 15 ... Omnicell, Inc., (Nasdaq: OMCL ) a leading ... announced the Omnicell WorkflowRx (TM) 6.0 ...
... Early results from the second series of trials have ... a 4.4 log reduction (99.994%) in Methicillin Resistant Staph Aureus ... medical treatment facilities world wide with the spread of MRSA ... CDC reported (JAMA 2007) that MRSA alone is now associated ...
... considering hair replacement surgery is certain to have lots of questions ... it is called "surgery" causes a person to wonder, "Is Hair ... questions that we have regarding hair replacement ," ... explains, "People want to know that they are going to be ...
... Products announced today the first commercial, plant-based diamine oxidase (DAO). ... reports that this new diamine oxidase is orders of magnitude ... enzyme is available as a lyophilized powder. Price will be ... for test assays to detect spoilage by the presence of ...
Cached Medicine News:Health News:Cleveland Residents Lining up to Help Save a Life with Free Donor Kits 2Health News:Boston Scientific's Urology/Gynecology Products Featured in Studies at International Urogynecological Association Annual Meeting 2Health News:Boston Scientific's Urology/Gynecology Products Featured in Studies at International Urogynecological Association Annual Meeting 3Health News:Boston Scientific's Urology/Gynecology Products Featured in Studies at International Urogynecological Association Annual Meeting 4Health News:Boston Scientific's Urology/Gynecology Products Featured in Studies at International Urogynecological Association Annual Meeting 5Health News:Boston Scientific's Urology/Gynecology Products Featured in Studies at International Urogynecological Association Annual Meeting 6Health News:Omnicell Boosts Pharmacy Efficiency with Enhanced WorkflowRx(TM) Central Pharmacy Automation Software 2Health News:Omnicell Boosts Pharmacy Efficiency with Enhanced WorkflowRx(TM) Central Pharmacy Automation Software 3Health News:Medizone Announces That Its AsepticSure(TM) Development Program is Reaching Objectives on Two Fronts 2Health News:USHairReplacement.com Provides Wealth of Knowledge to Common Hair Replacement Questions 2
(Date:5/20/2013)... 20, 2013  AbbVie (NYSE: ABBV ... 3 clinical study called SONAR (Study Of Diabetic ... the investigational compound atrasentan - when added to standard ... patients with stage 2 to 4 chronic kidney ... a large, multinational, double-blind, placebo-controlled clinical study that ...
(Date:5/19/2013)... 20, 2013 Claret Medical, Inc. announced the publication ... Mieghem et al., Histopathology of Embolic Debris ... print in Circulation, May 7 th this research is ... Rotterdam, the Netherlands and the pathology team ... Cardiovascular Pathology Institute, Gaithersburg, Maryland.  This is ...
(Date:5/18/2013)... , May 18, 2013 Although colonoscopy exams ... considered the most sensitive method for detecting colorectal cancers ... preventing cancer cases 3 . EndoChoice ® Inc. ... system significantly improves the accuracy of this procedure and ... EndoChoice will be discussing these clinical trial results and ...
Breaking Medicine Technology:AbbVie Initiates Phase 3 Study of Its Investigational Compound Atrasentan on Renal Outcomes in Patients with Diabetic Nephropathy 2AbbVie Initiates Phase 3 Study of Its Investigational Compound Atrasentan on Renal Outcomes in Patients with Diabetic Nephropathy 3AbbVie Initiates Phase 3 Study of Its Investigational Compound Atrasentan on Renal Outcomes in Patients with Diabetic Nephropathy 4AbbVie Initiates Phase 3 Study of Its Investigational Compound Atrasentan on Renal Outcomes in Patients with Diabetic Nephropathy 5AbbVie Initiates Phase 3 Study of Its Investigational Compound Atrasentan on Renal Outcomes in Patients with Diabetic Nephropathy 6Claret Medical, Inc. Announces Publication of the First Clinical Research on the Frequency and Composition of Embolic Debris Captured during TAVR 2New Study Shows Full Spectrum Endoscopy Procedure Reduces The 'Miss Rate' of Adenomas During Colonoscopy 2New Study Shows Full Spectrum Endoscopy Procedure Reduces The 'Miss Rate' of Adenomas During Colonoscopy 3
... , July 19, 2010 Today, Novo Nordisk announced the,landmark recruitment of ... effects of modern insulins in,the management of type 2 diabetes.[1] , ... Spanning 28 countries across 4 continents and involving ... therapy. , , , ...
... Focused Ultrasound Surgery Foundation has announced that eight leading manufacturers are ... Focused Ultrasound, scheduled for October 17 through 20 near ... , , ... edge preclinical, translational and clinical research related to one of today,s ...
Cached Medicine Technology:World's Largest Study on Insulin Therapy Completes Recruitment With 60,000 Patients 2World's Largest Study on Insulin Therapy Completes Recruitment With 60,000 Patients 3MR-Guided Focused Ultrasound Symposium Announces Sponsors 2MR-Guided Focused Ultrasound Symposium Announces Sponsors 3
Adjustable tilt angle 0 to 20 Adjustable speed of 3-25 RPM Load capacity: 2.7 kg (6 lbs.) Ambient temperature range 4C to 65C Low voltage power is supplied by wall mount transformer...
Conversion Kits For Modular Incubator Chamber...
... The AutoIncubator 96 can incubate and shake ... prepare 96 samples at a time. This ... and enzyme reactions, such as Proteinase K digestion. ... extraction process by preparing your samples with our ...
Inquire...
Medicine Products: