Navigation Links
First comprehensive review of European breast cancer screening programs finds benefits outweigh harm
Date:9/12/2012

A major review of breast cancer screening services in Europe, jointly led by researchers at Queen Mary, University of London, has concluded that the benefits of screening in terms of lives saved outweigh the harms caused by over-diagnosis.

The results, which are published in a special supplement of The Journal of Medical Screening [1] today (Thursday), show that for every 1,000 women screened every two years from the age of 50 to the age of about 68-69, between seven and nine lives would be saved, and four cases would be over-diagnosed.

The European Screening Network (EUROSCREEN) working group [2], with members from nine European countries where outcome of screening programmes have been assessed, reviewed the estimates of benefit in published European studies in terms of breast cancer deaths prevented, and the major harms, in particular, the rates of what are called "over-diagnosed" cancers. These are breast cancers diagnosed as a result of screening, which would never have given rise to any symptoms during a woman's lifetime and would not have been diagnosed had she not been screened.

A second working group European Network for Indicators on Cancer (EUNICE) reviewed the organisation, participation rates and main performance parameters of 26 screening programmes in 18 countries, involving 12 million women, between 2001 and 2007 [3]. The reports from both working groups have contributed to the review published today.

Stephen Duffy, Professor of Cancer Screening at the Wolfson Institute of Preventive Medicine at Barts and The London School of Medicine & Dentistry, part of Queen Mary, University of London (UK), who is one of the coordinators of the EUROSCREEN working group and co-author of the supplement, said: "This is the only comprehensive review of the results of breast screening services in Europe. It reports results from screening millions of women, and confirms that the screening services are delivering the benefits expected from the research studies conducted years ago. In particular, it is good news that lives saved by screening outweigh over-diagnosed cases by a factor of two to one."

The researchers also found that for every 1,000 women screened, 170 women would have at least one recall followed by a non-invasive assessment before absence of cancer could be confirmed (a negative result), and 30 women would have at least one recall followed by invasive procedures, such as a biopsy, before confirming a negative result. Screening results that lead to recalls in these circumstances are called "false positives" and can cause women stress and anxiety until the negative result is confirmed.

Dr Eugenio Paci, Director of the Cancer Prevention and Research Institute in Florence, Italy, who is a second EUROSCREEN coordinator and co-author, said: "By weighing up the pros and cons of breast cancer screening programmes we hope to ensure that women are fully aware of the chief benefits and harms and can make a fully informed choice when they decide whether or not they wish to attend screening. There has been quite a lot of discussion recently over the worth of breast cancer screening and for this reason it is timely that the international group of experts has assessed the impact of population-based screening in Europe and has found that it is contributing to the reduction in deaths from the disease.

"We believe that not only should our conclusions be communicated to women offered breast screening in Europe, but that, in addition, communication methods should be improved in order to raise women's awareness, and to make information more accessible, relevant and comprehensible."


'/>"/>
Contact: Emma Mason
e.mason@qmul.ac.uk
Queen Mary, University of London
Source:Eurekalert

Related medicine news :

1. First pediatric study to look at the role of vitamin D in critical illness
2. Researchers find first evidence for a genetic cause for Barretts esophagus
3. London Olympics anti-doping labs set for first-of-a-kind repurposing
4. First validated method for analyzing flavanols and procyanidins in cocoa products could help scientists and the industry in standardized reporting
5. NIH scientists map first steps in flu antibody development
6. Likely voters say presidents first 100 days in office should include plans for research
7. First evidence from humans on how alcohol may boost risk of cancer
8. First identification of a strong oral carcinogen in smokeless tobacco
9. IHME professor named first health measurement winner of prestigious innovation award
10. FDA Gives Nod to First Drug for Diabetic Eye Disease
11. Mayo Clinic completes first genome-wide analysis of peripheral T-cell lymphomas
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... Brooklyn, NY (PRWEB) , ... June 27, 2016 ... ... is using cutting edge technology to revolutionize the emergency ambulance transport experience for ... Many are aware of how Uber has disrupted the taxi industry through the ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned by ... to enhance the health of felines. The formula is all-natural and is made from ... the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract ...
(Date:6/25/2016)... ... 25, 2016 , ... The temporary closing of Bruton Memorial Library on June 21 due to ... a new, often overlooked aspect of head lice: the parasite’s ability to live away from ... common occurrence, but a necessary one in the event that lice have simply gotten out ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, ... at Work award to iHire in recognition of their exemplary accomplishments in worksite health ... annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her ... would lash out at his family verbally and physically. , “When something upset him, he ... he would use it. He would throw rocks at my other children and say he ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016 According to a ... (Standard Pen Needles, Safety Pen Needles), Needle Length (4mm, ... Hormone), Mode of Purchase (Retail, Non-Retail) - Trends & ... studies the market for the forecast period of 2016 ... 2.81 Billion by 2021 from USD 1.65 Billion in ...
(Date:6/24/2016)... NAMUR , Belgium , ...  (NYSE MKT: VNRX), today announced the appointment of ... Board of Directors as a Non-Executive Director, effective ... the Company,s Audit, Compensation and Nominations and Governance ... Board, Dr. Futcher will provide independent expertise and ...
(Date:6/23/2016)... -- MedSource announced today that it has selected Datatrial,s ... choice.  This latest decision demonstrates MedSource,s commitment to ... by offering a state-of-the-art electronic data capture (EDC) ... the EDC platform of choice in exchange for ... long been a preferred EDC platform by our ...
Breaking Medicine Technology: