First Swedish Patients Receive MitraClip(... (g an open thorax. I am looking forward t...)

First Swedish Patients Receive MitraClip(R) Therapy

Date:8/24/2009

g an open thorax. I am looking forward to treat more patients to further evaluate this approach," said Dr. Hultman, Director of the Clinic in Cardiothoracic Surgery and Anesthesia. "It is very satisfactory for us as a unit to be able to offer this technology to some of our patients. The MitraClip(R) is a device that hopefully will enable us to design the optimal treatment for all different types of patients with MR including high risk and inoperable candidates," added Dr. Jonsson who led the team.

Evalve initiated commercial sales of the MitraClip(R) system in Europe under the CE Mark in late 2008. The company is employing a direct sales strategy and is taking a disciplined and measured approach to the initial commercial roll out. Evalve has worked closely with hospitals to deliver high quality training programs in preparation for the first series of implants and offers ongoing support. The MitraClip(R) device is currently being implanted in six Western European countries, including Germany, Italy, the United Kingdom, the Netherlands, Switzerland and now Sweden.

"We are very pleased with the successful initial use of the MitraClip(R) device in Sweden at this outstanding cardiac center," said Ferolyn Powell, president and chief executive officer of Evalve. "It is noteworthy that the MitraClip(R) therapy can be delivered to patients by both interventional cardiologists and cardiothoracic surgeons in close collaboration with their colleagues in echocardiology. The centers offering the MitraClip(R) therapy in Europe are pioneering a new field and era in the medical care for patients who suffer from mitral regurgitation, especially for those who, until now, had very limited therapeutic options."

About the MitraClip(R) Procedure

Percutaneous mitral repair with Evalve's MitraClip(R) device is performed by physicians in the catheterization laboratory. The heart beats normally during the procedure, and
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