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First NxStage Home Hemodialysis Patients Celebrate Five-Year Anniversary
Date:1/6/2009

"We look forward to expanding on the success of these patients to increase awareness and improve the quality of life for thousands of dialysis patients with our products."

About NxStage Medical

NxStage Medical, Inc. (Nasdaq: NXTM) is a medical device company, headquartered in Lawrence, Massachusetts, USA, that develops, manufactures and markets innovative products for the treatment of end-stage renal disease, or ESRD, and acute kidney failure. For more information on NxStage and its products, please visit the company's website at http://www.nxstage.com.

The patient testimonials included in this release are examples of patient experiences on daily home hemodialysis with the NxStage System One. All patient experiences will vary, and there can be no assurance that all patients will experience these benefits. All hemodialysis involves some risk, and patients are encouraged to speak with their physicians to see if home dialysis with the NxStage System One is right for them.

Forward-Looking Statements

This release contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this release that are not clearly historical in nature are forward-looking, and the words "anticipate," "believe," "expect," "estimate," "plan," and similar expressions are generally intended to identify forward-looking statements. Actual results may differ materially from those indicated by these forward-looking statements as a result of various important factors including, but not limited to: market acceptance of the NxStage System One, the anticipated impact and results of daily hemodialysis, and other factors that are discussed in NxStage's filings with the Securities and Exchange Commission,
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SOURCE NxStage Medical, Inc.
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