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First Look at Prostate Cancer Genome Yields Insights
Date:2/9/2011

Prostate cancer causes more than 30,000 deaths in the United States annually, according to background information in the article. More than 200,000 men are diagnosed each year.

Currently, it's difficult for physicians to know if prostate cancer is going to be slow-growing, in which case doctors may monitor but not treat it, or if it will be aggressive, in which case surgery and chemotherapy may be needed, said Dr. Anna Ferrari, director of the Genitourinary Cancer Program at the NYU Cancer Institute.

The researchers "have done a complete sequencing of the genome in prostate cancers that are very aggressive, and they found in addition to the already established alterations, new genes and new pathways that may influence the progression of the disease," Ferrari said. "This may point to new targets for drug development and treatment strategies."

More information

The U.S. National Cancer Institute has more on prostate cancer.

SOURCES: Michael F. Berger, Ph.D., assistant professor, pathology, Memorial Sloan-Kettering Cancer Center, New York City; William Phelps, Ph.D., program director, Translational and Preclinical Cancer Research, American Cancer Society, Atlanta; Anna C. Ferrari, M.D., director, Genitourinary Oncology Program, NYU Cancer Institute, New York City; Feb. 10, 2011, Nature


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