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First Global Atrial Fibrillation Registry, RecordAF, Shows Rhythm-Control Strategy With Current Therapies Achieves Improved Disease Control but not Clinical Outcomes
Date:11/15/2009

inus 2 months) -not mandatory- , and 12 months (plus or minus 3 months).

About atrial fibrillation

Atrial fibrillation is the most common cardiac arrhythmia and affects nearly 7 million people in the European Union and the United States.[1],[6] AF currently represents a major economic burden for society and leads to potential life-threatening complications. AF increases the risk of stroke up to five-fold4, worsens the prognosis of patients with CV risk factors[1],[3], and doubles the risk of mortality[5] with significant burden on patients, health care providers and payers. Hospitalizations for AF have increased dramatically (two-to-three-fold) in recent years.[2],[7] AF hospitalizations now represent a third of all hospitalizations for arrhythmia and mortality in the US and Europe.[1] Seventy percent of the annual cost of AF management in Europe is driven by hospital care and interventional procedures.[8]

References ---------------------------------

[1] Fuster V et al. ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation. European Heart Journal (2006) 27, 1979-2030.

[2] Wattigney WA, Mensah GA & Croft JB. Increasing trends in hospitalization for atrial fibrillation in the US 1985 through 1999 Implications for primary prevention. Circulation. 2003;108:711-716.

[3] Dorian P et al. J Am Coll Cardiol. 2000;36:1303-1309

[4] Lloyd-Jones et al. Lifetime Risk for Development of Atrial Fibrillation: The Framingham Heart Study. Circulation. 2004; 110:1042-1046.

[5] Benjamin EJ, Wolf PA, D'Agostino RB, Silbershatz H, Kannel WB, Levy D. Impact of atrial fibrillation on the risk of death: the Framingham Heart Study. Circulation 1998 Sep 8; 98(10):946-52.

[6] Go AS, Hylek EM, Phillips KA, et al. Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke
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