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First-Ever Standardized Scales to Measure the Skin's Aging Process Are Introduced at the American Society for Aesthetic Plastic Surgery's Annual Meeting
Date:5/4/2009

the world trained in multiple specialties (including dermatology, ophthalmology, plastic surgery, and dermatologic surgery) came together to create and validate a comprehensive scale system, reviewing and including photographs of men and women of diverse ages, skin types and ethnicities. As part of this process, the experts rated 35 to 50 real-life images of people, and evaluated the images for reproducibility of results.

The Merz Scales were then generated as five-point scales using computer-morphed photography. Specific anatomical changes related to aging were identified and were incorporated into the photographs, and a series of visual guides were developed to correspond to regional areas on the face and hands. When "lines" were formed as a result of the different movements of different muscle groups, such as crow's feet and forehead lines, static and dynamic lines were included. For example, The Forehead Lines Grading Scale was developed to objectively quantify resting (static) and hyperkinetic (dynamic) forehead lines. The scale ratings are 0 for no wrinkles, 1 for no wrinkles present at rest but fine lines with facial expressions, 2 for fine wrinkles present at rest and deep lines with facial expression, 3 for fine wrinkles present at rest and deeper lines with facial expression and 4 for deeper wrinkles at rest and deeper furrows with facial expression.

Every participant graded the scales twice, with an overnight break in between. Intra and interrater variability analysis was performed. The variability analysis also was depicted in a bubble plot, which is an informative way of comparing grading between raters.

About Merz

Merz Pharmaceuticals, part of the Merz group of companies based in Frankfurt Germany, has a 100-year history of compassion and innovation in healthcare. The ongoing development of The Merz Scales represents the company's ongoing, deep
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SOURCE Merz Pharmaceuticals
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