Navigation Links
Fipronil and imidacloprid reduce honeybee mitochondrial activity
Date:8/6/2014

PENSACOLA, Fla. New research published in Environmental Toxicology and Chemistry addresses the effects of two broad-spectrum systemic insecticides, fipornil and imidacloprid, on honeybees. These insecticides are widely used in agriculture, and the authors conclude that fipronil and imidacloprid are inhibitors of mitochondrial bioenergetics, resulting in depleted cell energy. This action can explain the toxicity of these compounds for honeybees.

Scientists are urgently trying to determine the causes of colony collapse disorder and the alarming population declines of honeybees. The cross-pollination services they provide are required by approximately 80 percent of all flowering plants, and 1/3 of all agricultural food production directly depends on bee pollination. As a result, there has been a flurry of research on honeybee parasitic mite infestations, viral diseases, and the direct and indirect impacts of pesticides.

The effects of pyrazoles (e.g., fipronil) and neonicotinoids (e.g., imidacloprid) on the nervous system are fairly well documented. Daniel Nicodemo, professor of ecology and beekeeping at the Universidade Estadual Paulista in Dracena, Brazil, and lead author of the study states, "These insecticides affect the nervous system of pest and beneficial insects, often killing them. Sublethal effects related to insect behavior have been described in other studies; even a few nanograms of active ingredient disturbed the sense of taste, olfactory learning and motor activity of the bees." A key characteristic of colony collapse disorder is the incapacity of the honeybees to return to their hives, and these disruptions have a direct impact on that ability.

In this study, Nicodemo et al. looked at the effects of fipronil and imidacloprid on the bioenergetics functioning of mitochondria isolated from the heads and thoraces of Africanized honeybees. Mitochondria are the power plants of a cell, generating most of a cell's supply of adenosine triphosphate (ATP), used as a source of chemical energy.

Honeybee flight muscles are strongly dependent on high levels of oxygen consumption and energy metabolism. Mitochondrial oxidative phosphorylation drives ATP synthesis, which is required to contract the muscles during flight. "If something goes wrong, the energy production is impaired," explains Nicodemo. "Similar to a plane, honeybees require clean fuel in order to fly." Both fipronil and imidacloprid negatively affected the mitochondrial bioenergetics of the head and thorax of the honeybees. While at sublethal levels, insecticide damage may not be evident, even such low level exposure clearly contributes to the inability of a honeybee to forage and return to the hive, which could result in declining bee populations.


'/>"/>

Contact: Jennifer Lynch
jen.lynch@setac.org
850-469-1500 x109
Society of Environmental Toxicology and Chemistry
Source:Eurekalert

Related medicine news :

1. Production and Market of Imidacloprid in China
2. Community pharmacist intervention boosts drug adherence, reduces health-care costs
3. Diet change -- A solution to reduce water use?
4. 5 Tips for Back-to-School: What You Need to Know to Reduce Stress and Plan for a Healthy Transition from Nina Radcliff, MD
5. Eating resistant starch may help reduce red meat-related colorectal cancer risk
6. Algorithm reduces use of CT scans when diagnosing children with appendicitis
7. Cataract Surgery: New Technology for Reduced Dependence on Glasses
8. New Standing Desk Anti-fatigue Mats from Martinson-Nicholls Reduce Leg Fatigue and Discomfort Working at Standing and Sit-to-Stand Desks
9. Surgical safety program greatly reduces surgical site infections for heart operations
10. Full Explanation Reduces Seniors’ Worries about Lung Cancer Screening
11. Seeing the same GP at every visit will reduce emergency department attendance
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/25/2017)... ... 25, 2017 , ... Leonard Bley, MD with ... for LASIK in Manhattan with Contoura Vision, the latest WaveLight® topographic-guided laser system ... in the United States to correct nearsightedness and nearsightedness with astigmatism. This state-of- ...
(Date:9/25/2017)... ... ... Dr. Edward Hebert is celebrating his 33rd anniversary as a ... Dr. Hebert. “I count my blessings daily for the opportunity that the field of ... I look forward to the most. The relationships I have with my patients is ...
(Date:9/25/2017)... ... September 25, 2017 , ... “The Ministry of ... gripping look at the religious stand in the sensitive matter of sexual discrimination, ... “The Ministry of Reconciliation: A Compassionate and Realistic Approach to Evangelizing the LGBTQ ...
(Date:9/25/2017)... ... ... “The Majestic Unicorn”: a poignant book that describes what happened to the ... published author, Dayna Chantel, an artist and a writer. , Chantel shares, “Animals of ... cypress ark-vessel. Male and female, no matter what species, they were chosen to be ...
(Date:9/25/2017)... ... September 25, 2017 , ... The trend-spotters, tastemakers, and ... maker of organic coconut-milk based super herb drinks, with the new NEXTY Gold Award ... the inaugural year for the NEXTY Gold, which is reserved for just those companies ...
Breaking Medicine News(10 mins):
(Date:9/9/2017)... Sept. 8, 2017 Dealmed Medical Supplies, ... of medical equipment, supplies, drugs, vaccines, and specialty medical ... into an agreement to acquire Vantage Medical Supplies, a ... Holtsville, New York . ... new and emerging medical practices, will operate under the ...
(Date:9/7/2017)... INDIANAPOLIS , Sept. 7, 2017  Eli ... today announced actions to streamline operations to more ... to improve its cost structure. Global workforce reductions, ... program, are expected to impact approximately 3,500 positions. ... the company expects annualized savings of approximately $500 ...
(Date:9/7/2017)... 7, 2017 Caris Life Sciences, a ... the promise of precision medicine, today announced results ... of its molecular profiling approach in guiding therapeutic ... profiling plus (CGP+) with Caris Molecular Intelligence ® ... a molecular level, leading to more therapeutic options ...
Breaking Medicine Technology: