Navigation Links
Fine-tuning treatments for depression
Date:10/18/2009

CHICAGO -- New research clarifies how neurotransmitters like norepinephrine, serotonin, and dopamine, are regulated a finding that may help fine-tune therapies for depression.

Current drugs for depression target the regulatory process for neurotransmitters, and while effective in some cases, do not appear to work in other cases.

Recent findings suggest that synucleins, a family of small proteins in the brain, are key players in the management of neurotransmitters -- specifically, alpha- and gamma-synuclein. Additionally, researchers have found elevated levels of gamma-synuclein in the brains of both depressed animals and humans.

In a study presented at the 39th annual meeting of the Society for Neuroscience, Georgetown University Medical Center researchers observed increased depressive-like behavior in mice where gamma-synuclein acts alone to regulate neurotransmitters, confirming earlier studies by this group.

"These findings show the importance of, and clarify a functional role for, gamma synuclein in depression and may provide new therapeutic targets in treatment of this disease," says Adam Oaks, a student researcher in the Laboratory of Molecular Neurochemistry at GUMC. "Understanding how current therapies work with the synucleins is important because the drugs don't work for all patients, and some are associated with side effects including an increased risk of suicide."


'/>"/>

Contact: Karen Mallet
km463@georgetown.edu
215-514-9751
Georgetown University Medical Center
Source:Eurekalert

Page: 1

Related medicine news :

1. Fine-Tuning Prosthetic Hands to Restore a Sense of Touch
2. Studying cancer in pet dogs to find new treatments for human patients
3. DNA test could be key to targeting treatments for head and neck cancer
4. Chronic pain treatments work better together, says anesthesiologist
5. $16.8 million grant awarded to develop platelet recovery treatments
6. Dr. Marc Katz, Leading Podiatric Surgeon Adds High Powered Color Ultrasound To Cryosurgery Procedures and Treatments
7. New Treatments Hold Hope for Failing Eyes
8. National Autism Center Releases Groundbreaking Report on Autism Treatments
9. Women's Pelvic Organ Prolapse and Incontinence Guide Informs, Outlines Treatments
10. A Dementia That Afflicts Younger Population Has Similarities to Alzheimers, Applicable Treatments
11. Guatemala Treatment Center Becomes First in Latin America to Introduce Fast and Precise RapidArc Radiotherapy Cancer Treatments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/2/2016)... ... May 02, 2016 , ... Dr. Jonathan Kulbersh of Carolina Facial Plastics isn’t surprised ... five on the list of “ 5 US Cities with the Highest Plastic Rates .” ... and Miami. The results were calculated using a survey by RealSelf and ...
(Date:5/2/2016)... ... May 02, 2016 , ... MedaCheck, a leading medication ... outcomes, has announced its partnership with GrandView Health Services. , With decades of ... counter and prescription drug pharmacy services to thousands of residents. Serving Indiana, Ohio, ...
(Date:5/2/2016)... ... May 02, 2016 , ... The Evolve Paddle Board Company- which specializes ... today the outcome of their partnership with Yoloha Yoga- producers of high quality cork ... , SUP yoga has seen a dramatic rise in popularity throughout the last few ...
(Date:5/2/2016)... ... May 02, 2016 , ... One of Hollywood’s best kept ... Dermatology Surgery & Laser Center, in Milford, Penn. “Patients with busy lives want noninvasive ... fat treated and go home or back to work without having to wear recovery ...
(Date:5/2/2016)... Worcester, MA and Shelton, CT (PRWEB) , ... May 02, 2016 ... ... Scott Krug, President and Owner of New England Low Vision and Blindness (NELV&B) ... location will add more flexibility and convenience for people with vision impairments to get ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... 28, 2016 , Net Sales of $1.90 ... over the prior year period, and an increase of 1.2% ... Diluted EPS for the first quarter were $0.52 reported, a ... adjusted, an increase of 29.9% over the prior year period ... earnings guidance for 2016 Zimmer Biomet Holdings, Inc. ...
(Date:4/28/2016)... Florida , April 28, 2016 ... the development of innovative peptide and gene-based immunotherapeutics and vaccines ... it will be presenting at the 3rd Annual Growth ... - 5 th , 2016 at Caesars Palace in Las Vegas, ... 8.00 am on Wednesday, May 4 th by Dr. ...
(Date:4/27/2016)... 27, 2016   ... in Recurring Consumable Sales  Clinical sales grow ... Technologies (Euronext: MKEA, OTCQX: MKEAY) inventor of Cellvizio®, the ... for the first quarter ended March 31, 2016 and ... of its commercial strategy. First Quarter 2016 ...
Breaking Medicine Technology: