Navigation Links
Findings on HIV-Resistant Sex Workers May Help Vaccine Efforts
Date:2/16/2012

THURSDAY, Feb. 16 (HealthDay News) -- In studying how HIV is transmitted, researchers have discovered that some African sex workers are naturally resistant to the virus, a finding that could influence prevention efforts.

These women are protected by an unusually weak inflammatory response in their vaginas, the scientists noted.

"In this part of the world, women represent over 60 percent of HIV cases, and this proportion continues to increase," Dr. Michel Roger, of the University of Montreal Hospital Centre and its microbiology and immunology department, in a news release. "Studying women who are naturally resistant to the virus enables researchers to identify interesting information in terms of developing vaccinations or microbid gels that could prevent transmission of HIV."

The researchers followed women from Benin and Zimbabwe over the course of 15 years. They found that when some of these women are exposed to HIV, the immune-system cells in their vaginas produced fewer inflammatory molecules than the cells in women infected with the virus.

Although these molecules are usually helpful by activating lymphocyte T-cells that destroy viruses, HIV actually uses these T-cells to invade people's bodies, the researchers said.

"Fewer T-cells means fewer target cells available for the virus to use," Roger explained.

The researchers also found the women's immune response in their vaginas -- where the virus entered their body -- was different from their body's response once the virus was in their bloodstream. The study concluded that a better way to stop the spread of HIV would be to block the virus from entering the body, rather than fight it once it had already invaded.

"AIDS vaccination research has entirely focused on the bloodstream and this approach has been a failure," Roger said. "Our research shows that the immune response is different at the site of the infection, and that we should turn to the entry points in order to find a means for blocking the virus."

The researchers said that the body's mucus membranes would be protected through a through a nasal-spray vaccine.

They added that more research is needed to fully understand the immune response in the vagina and determine if women's DNA plays a role in natural HIV resistance.

The results were recently published in the journal PLoS ONE.

More information

The U.S. Centers for Disease Control and Prevention provides more information on HIV and AIDS.

-- Mary Elizabeth Dallas

SOURCE: University of Montreal, news release, Feb. 13, 2012.


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Georgetown Lombardi researchers present new findings on head & neck cancers
2. Van Andel Research Institute findings provide more complete picture of kidney cancer
3. UK researchers present findings from Kentucky breast cancer patients with disease relapse
4. Scar findings could lead to new therapies, Stanford researchers say
5. Society for Integrative Oncology releases findings presented at annual meeting
6. Many radiologists disagree on management of incidental findings, study finds
7. New findings could lower risk of suicide in men with prostate cancer
8. Virginia Commonwealth University findings may help explain high blood pressure in pregnancy
9. UC Berkeley findings offer new clues into the addicted brain
10. New findings contradict dominant theory in Alzheimers disease
11. Python Findings Shed Light on Human Heart Health
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Findings on HIV-Resistant Sex Workers May Help Vaccine Efforts
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term ... long-term care insurance companies have a waiver for care if the client has a ... when the family pays for care, is often waived, so the benefits from their ...
(Date:10/13/2017)... ... ... Talented host, actor Rob Lowe, is introducing a segment ... of "Success Files," which is an award-winning educational program broadcasted on PBS Member ... with passion and integrity. , Sciatica occurs when the sciatic nerve in the ...
(Date:10/12/2017)... ... 12, 2017 , ... CitiDent and San Francisco dentists, Dr. ... Oventus O2Vent technology. As many as 18 million Americans are estimated to suffer ... Oral appliances can offer significant relief to about 75 percent of people with ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, a nationally ... care, have expanded their existing home health joint venture through an agreement, effective ... operating a joint venture home health company with Asante, delivering clinically integrated care, ...
(Date:10/12/2017)... Chapel, FL (PRWEB) , ... October 12, 2017 , ... ... is holding a treadmill relay – Miles by Moonlight to raise money for the ... donating $300 or more. , Teams will work together to keep their treadmills ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... SEOUL, South Korea , Oct. 4, 2017 /PRNewswire/ ... launched its next-generation CPR training aide "cprCUBE" on Kickstarter. ... of chest compression during cardiac arrests with better efficiency ... patient-mannequins. It also offers real-time feedback on efficacy of ... The crowdfunding campaign has a goal to raise ...
(Date:10/2/2017)... 2, 2017  Eli Lilly and Company (NYSE: ... the third quarter of 2017 on Tuesday, October 24, ... that day with the investment community and media to ... conference call will begin at 9 a.m. Eastern time. ... live webcast of the conference call through a link ...
(Date:9/28/2017)... Sept. 28, 2017 Hill-Rom Holdings, Inc. (NYSE: ... conference call and webcast on Friday, November 3, 2017, ... and ending at approximately 8:30 a.m. (CDT) / 9:30 ... company,s 2017 financial performance and guidance for 2018, Hill-Rom ... to enhance operational performance, and long-range financial outlook through ...
Breaking Medicine Technology: