Navigation Links
Finding the source: Cells that initiate a common infant tumor identified
Date:6/5/2008

Infantile hemangiomas, exemplified by the strawberry-like patches that appear on the skin of infants soon after birth, are benign tumors that develop in 5%-10% of Caucasian infants and usually disappear by the age of 9 without treatment. Joyce Bischoff and colleagues, at Children's Hospital Boston, have now identified the cells that give rise to these tumors and used them to develop a new mouse model of this disease.

Cells expressing the protein CD133 were isolated from infantile hemangioma tissue and individual cells were grown separately in culture. After each cell had been grown long enough for it to have given rise to a large population of cells, the cells were transplanted into immunodeficient mice, where they generated human blood vessels. Overtime, the number of blood vessels decreased and fat cells became evident. As these observations recapitulate those made in individuals with infantile hemangioma where blood vessels form and then disappear leaving behind fat cells the authors conclude that a single cell can give rise to infantile hemangioma and that their new model of these tumors will help identify therapeutic targets.


'/>"/>

Contact: Karen Honey
press_releases@thje-jci.org
215-573-1850
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related medicine news :

1. Senesco Expands on Preclinical Multiple Myeloma Findings
2. Finding clues for nerve cell repair
3. NYP/Weill Cornell physician-scientists present latest cancer findings at ASCO meeting
4. Dartmouth-Hitchcock Medical Center Evaluation Findings Demonstrate Masimo Patient SafetyNet(TM) Delivers Improvements in Clinical Outcomes and Patient Safety on General Care Floors
5. Stop Obesity Alliance, Chair Dr. Richard H. Carmona, National Opinion Research Center Reveal Findings of Survey Showing Employer Concern About Health, Financial Costs of Obesity
6. Aspen Institute to Release Presidential Candidates Responses to Health Care Reform Questionnaire; New Zogby Poll Findings Also to be Released
7. Open Hearings, Fact-Finding Today by SEIU Long Term Care Workers Continues Democratic Process Begun in 2006
8. Marketing Executives Finding Value in Best Practice Database
9. New findings: The anti-fibrotic mechanism of plant extract Cpd 861
10. Study shows positive findings in treating patients with advanced hepatitis C
11. Remuda Programs for Eating Disorders and FINDINGbalance Partner to End Poor Self Image
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/26/2017)... Pittsburgh, PA (PRWEB) , ... September 26, 2017 ... ... new chairmen who are collaborating on strategic and tactical plans for Pittcon 2018. ... Chemistry), took office as president along with his named vice president, Charles Gardner, ...
(Date:9/26/2017)... ... September 26, 2017 , ... “Sound of My Song”: ... the creation of published author, Karmen Worden, a retired teacher with a passion for ... book is an intriguing and inspiring story on loss, living with depression, and finding ...
(Date:9/26/2017)... ... ... Lion, the Lamb, and the Rose”: a charming tale of three animals, each with the ... and the Rose” is the creation of published author, Ieshia Greaves, a mother and United ... book touches the hearts of children and adults, there is a lesson for everyone to ...
(Date:9/25/2017)... , ... September 25, 2017 , ... ... Arizona State University student Ashlea Grabau. The $1000 student scholarship is awarded each ... scholarship was awarded to Ashlea Grabau who is a medical student at Arizona ...
(Date:9/25/2017)... ... September 25, 2017 , ... SyncDog, Inc., ... SentinelSecure™, version 3.0, will be available in a managed cloud services model, available ... comes with several new enhancements including support for caller ID and network sharing ...
Breaking Medicine News(10 mins):
(Date:9/5/2017)... , Sept. 5, 2017 Sapheneia and Scannerside ... solution. Scannerside DoseCheck is a third-party Vendor neutral CT ... scanners and allows compliance with current MITA standards. ... XR 29 DoseCheck solution is specifically designed to provide ... of potential radiation doses over a predefined threshold. Scannerside ...
(Date:9/5/2017)... , Sept. 5, 2017  Just 18 months after ... is pleased to announce the appointment of three new ... Wynne , Dominic Jones-Phillips and James ... Tammy Wynne ... of market access writers. She has over ten years, ...
(Date:9/1/2017)... Sept. 1, 2017  Explorers Like Us ( https://explorerslikeus.com/ ) ... aural experiences — and deliver these experiences as part of ... people feel and heal better. ... While nothing beats a walk, jog or ... mind, Life Environments™ is the next best thing when getting ...
Breaking Medicine Technology: