Navigation Links
Finding Raises Hope for Treating ALS
Date:6/15/2009

Time between onset and symptoms could be targeted for therapy, study suggests,,

MONDAY, JUNE 15 (HealthDay News) -- Researchers now believe that ALS, or amyotrophic lateral sclerosis, starts well before its debilitating symptoms appear, a finding that they say could eventually lead to an effective treatment.

Protein clumps in cells that show up only after damage has occurred, rather than at the onset of the disease, appear responsible for the paralyzing course of ALS (amyotrophic lateral sclerosis), according to University of Florida researchers.

The research team found that the formation of these clumps of defective proteins and cell matter, called "protein aggregates," actually signals that ALS is progressing at a rapid pace.

In ALS, nerve cells extending from the brain to the spinal cord and then to the muscles die off. Its cause is unknown, though an inherited defective gene is suspected in up to 20 percent of cases. Scientists thought it originated with malformed -- or "misfolded" -- proteins that malfunction and lead to the protein aggregates in the brain.

The ALS Association says that about 30,000 Americans have the disease, which is often referred to as Lou Gehrig's disease, after the renowned ballplayer who died of ALS.

The Florida researchers examined the gene that produces superoxide dismutase 1, or SOD1, an enzyme that fights off free radicals -- molecules that damage the body's cells. People with the inherited version of ALS have been found to have one of the 146 known mutations in the SOD1 gene.

In the online edition of Human Molecular Genetics, the researchers wrote that the SOD1 mutations most likely to cause the protein clumps were also linked to the disease's faster progression.

Another study, recently published online in the Proceedings of the National Academy of Sciences, found that mice genetically altered to have ALS experience c
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Perrier Refutes Consumer Council Findings
2. Finding May Lead to Vaccine for Travelers Diarrhea
3. Finding Fitness on the Dance Floor
4. Findings in Epilepsy Gene in Animals May Guide Treatment Directions for Infants
5. Findings in epilepsy gene in animals may guide treatment directions for infants
6. Pitt melanoma researchers present novel findings at ASCO
7. Finding Hidden Heart Attacks: Saint Francis Hospital is First in Illinois to Detect Hidden Heart Attacks With New Technology
8. Finding a New Doctor Becoming More Difficult for Medicare Recipients Says MedicareSupplementPlans.com
9. Statement by American Legacy Foundation(R): Findings of Decades of Massive Fraud by Tobacco Industry Upheld in U.S. Court of Appeals
10. HIMSS Analytics and NetMotion Wireless Release Study Findings on Key Challenges for Wireless Healthcare Deployments
11. UCSF creates fast, affordable tool for finding gene on-off switches
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Finding Raises Hope for Treating ALS
(Date:10/22/2014)... The Louis W. Sullivan ... to distribute health information technology innovation to transform ... the development of six key guiding principles of ... healthcare. These are an expansion of the Institute ... that is respectful of and responsive to individual ...
(Date:10/22/2014)... 22, 2014 With the Affordable Care Act ... by the American Institutes for Research (AIR) finds that three ... use health insurance, but 42 percent say they are not ... before signing up for coverage. , The AIR survey found ... percent able to calculate correctly how much they owe for ...
(Date:10/22/2014)... 22, 2014 Best Cheap Hosting USA ... world. The site has recently announced that iPower ( ... for people from around the world. , “iPower is ... today and is providing various kinds of useful products ... insists on offering excellent customer service and a number ...
(Date:10/22/2014)... Losing Weight Your Body’s Way , In a world where ... it certainly can be difficult to choose the right weight ... by doing it the healthy way? Set aside the fads ... body, exercise regularly, and choose foods with the most nutritional ... need to exercise more and eat less. Despite the number ...
(Date:10/22/2014)... (PRWEB) October 22, 2014 Lintelus, Inc., ... Sr. Vice President of Sales, will be speaking on ... Meetings Technology Expo on October 28, at the Holiday ... hosting a booth as well as a Tech Demo ... Meeting can create a more engaging event experience. , ...
Breaking Medicine News(10 mins):Health News:The Sullivan Institute for Healthcare Innovation Announces Release of Guiding Principles for Patient Experience-Centered Care 2Health News:Many Americans Fail to Ask Basic Questions Before Signing Up for Health Insurance, National Survey Finds 2Health News:Many Americans Fail to Ask Basic Questions Before Signing Up for Health Insurance, National Survey Finds 3Health News:Many Americans Fail to Ask Basic Questions Before Signing Up for Health Insurance, National Survey Finds 4Health News:Best Cheap Hosting USA Has Recently Announced The Best Cheap Web Hosting Companies In 2014 2Health News:ReductionGuruMD Presents Ways to Improve Your Weight Loss Results 2Health News:Jay Cormier, Sr. Vice President of Sales for Lintelus, Speaks about Event Technology Integration at Meetings Technology Expo in NYC 2
... WASHINGTON, Nov. 8 Speaker Nancy Pelosi and Democratic leaders held ... Affordable Health Care for America Act. The bill passed by ... opening remarks: , "I and some of my colleagues just ... Obama, congratulating us on a great victory for the American people. ...
... ... Company’s Mississauga, Ontario facility. , ... Toronto, ON (PRWEB) November 8, 2009 -- Thomas Wellner, President and ... a commercial scale pharmaceutical grade freeze dryer and expects to make commercial scale freeze ...
... does not mean the battle is won," said Dr. Charmaine ... of 240-194, the Stupak-Ellsworth-Pitts-Kaptur-Dahlkemper-Lipinski-Smith Amendment to prohibit abortion mandates and ... Americans United for Life Action President and CEO Dr. Charmaine ... for the pro-life Americans across this country who have flooded ...
... of H.R. 3961 to Secure the Stability of Medicare ... Rohack, M.D., President, American Medical Association. , (Logo: ... of the House health reform bill, which will help improve ... swift passage of H.R. 3961 to secure the stability of ...
... Care Reform Bill , Critical legislation would ... BALTIMORE, Nov. 7 SUMMARY: Tonight the ... reform legislation that would strengthen Medicare for seniors and ... Americans out of affordable health coverage. , The Affordable ...
... The American Medical Association (AMA) today awarded its 2009 Benjamin ... Kraff, M.D., an ophthalmologist from Chicago, IL. The award recognizes ... of duty to make an outstanding public service contribution to ... the opening session of the 2009 Interim Meeting of the ...
Cached Medicine News:Health News:Therapure Biopharma Inc. Announces Delivery of its First Commercial-Scale Lyophilizer 2Health News:Americans United for Life Action Comments on Passage of Pro-Life Amendment: Bipartisan Pro-life Majority Reflects the Will of the American People 2Health News:AMA Hails House Passage of Health Reform Bill (H.R. 3962) 2Health News:AARP Maryland Key Vote News Alert 2Health News:AARP Maryland Key Vote News Alert 3Health News:AMA Honors IL Ophthalmologist Manus C. Kraff M.D. for Volunteer Eye Care for Military Members 2
(Date:10/22/2014)... Oct. 22, 2014   Reproductive Medicine Associates ... in the field of infertility, presents new clinical ... screening. The research abstract, released during the 70 ... (ASRM) meeting in Honolulu, Hawaii ... gene defect (SGD) pre-implantation genetic diagnosis (PGD). ...
(Date:10/22/2014)... , October 22, 2014 A ... Gloves Market (Product type, Form, End user, Application and ... Insights, Analysis, Research, Report, Opportunities, Segmentation and Forecast, 2013 ... gloves market. Based on key trends tracked, it is ... at $7.9 billion by 2020, registering a CAGR of ...
(Date:10/22/2014)... 2014   BioNano Genomics , the genome ... centers to purchase an Irys™ System . Among ... Institute (NCI), NIH Intramural Sequencing Center (NISC) and Genoscope ... a comprehensive view of a genome was a ... not deliver the scalability or reliability to detect ...
Breaking Medicine Technology:New IVF Research Highlights Improved Genetic Screening Approach To Help Parents Have Healthier Babies 2New IVF Research Highlights Improved Genetic Screening Approach To Help Parents Have Healthier Babies 3Global Disposable Gloves Market Expected to Grow to $7.9 Billion by 2020 - Allied Market Research 2Global Disposable Gloves Market Expected to Grow to $7.9 Billion by 2020 - Allied Market Research 3Global Disposable Gloves Market Expected to Grow to $7.9 Billion by 2020 - Allied Market Research 4BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 2BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 3
... Corporation (Nasdaq: THOR ), a world leader in ... failing hearts, said today it will be participating in the ... Wednesday, May 11. David V. Smith, executive vice ... the company, beginning at 8:40 a.m., Pacific Daylight Time (11:40 ...
... CINCINNATI, May 6, 2011 Kendle (Nasdaq: ... today announced the Company is postponing its Annual Meeting ... Research, LLC.  The annual meeting had been scheduled for ... 4, 2011, that it has signed a merger agreement ...
Cached Medicine Technology:Kendle Announces Postponement of 2011 Annual Meeting 2Kendle Announces Postponement of 2011 Annual Meeting 3Kendle Announces Postponement of 2011 Annual Meeting 4
Multispot HIV-1/HIV-2 is a rapid indirect EIA using recombinant and peptide antigens for simultaneous detection and differentiation of anti-HIV-1 and anti-HIV-2 antibodies in human serum or plasma....
Bio-Rad's Genetic Systems™ HBsAg EIA 3.0 screening and confirmatory assays offer outstanding sensitivity and early detection of HBV infection, helping to meet your testing criteria....
The most compact revolutionary innovation in hematology. 3 Part DIFF + CRP measurement on whole blood....
... Evolis™ is a self contained microplate ... based EIA assays. The system is dedicated ... encountered in todays busy laboratory. The system ... of EIA assays that satisfy their microplate ...
Medicine Products: